Patents by Inventor Michael D. Koob

Michael D. Koob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of introducing a mitochondrial genome into a eukaryotic cell mitochondrion
    Patent number: 9567590
    Abstract: The invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells, and organisms.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: February 14, 2017
    Inventors: Michael D. Koob, Young G. Yoon
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 9556488
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: January 31, 2017
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20140322711
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: April 28, 2014
    Publication date: October 30, 2014
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Laura P.W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 8748096
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: June 10, 2014
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20130230849
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: September 5, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Transgenomic Mitochondria, Transmitochondrial Cells and Organisms, and Methods of Making and Using
    Publication number: 20130203160
    Abstract: This invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells and organisms.
    Type: Application
    Filed: April 8, 2013
    Publication date: August 8, 2013
    Inventors: Michael D. Koob, Young G. Yoon
  • Transgenomic mitochondria, transmitochondrial cells and organisms, and methods of making and using
    Patent number: 8420377
    Abstract: The invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells, and organisms.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: April 16, 2013
    Inventors: Michael D. Koob, Young G. Yoon
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20130029335
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: August 20, 2012
    Publication date: January 31, 2013
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 8247173
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: August 21, 2012
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION
    Publication number: 20100317015
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: June 21, 2010
    Publication date: December 16, 2010
    Applicant: Regents of the University of Minnesota
    Inventors: LAURA P.W. RANUM, MICHAEL D. KOOB, KELLIE A. BENZOW, MELINDA L. MOSELEY-ALLDREDGE
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 7741458
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: June 22, 2010
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • Transgenomic Mitochondria, Transmitochondrial Cells and Organisms, and Methods of Making and Using
    Publication number: 20090098653
    Abstract: The invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells, and organisms.
    Type: Application
    Filed: April 15, 2005
    Publication date: April 16, 2009
    Inventors: Michael D. Koob, Young G. Yoon
  • SCA7 gene and methods of use
    Patent number: 7118893
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: October 10, 2006
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow
  • Spinocerebellar ataxia type 8 and methods of detection
    Publication number: 20030235841
    Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Application
    Filed: February 24, 2003
    Publication date: December 25, 2003
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SCA7 gene and methods of use
    Publication number: 20030180768
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Application
    Filed: February 3, 2003
    Publication date: September 25, 2003
    Applicant: Regents of the University of Minnesota
    Inventors: Laura P.W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow
  • Spinocerebellar ataxia type 8 and methods of detection
    Patent number: 6524791
    Abstract: The present invention provides an isolated nucleic acid molecule containing a a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: February 25, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Kellie A. Benzow, Melinda L. Moseley-Alldredge
  • SCA7 gene and methods of use
    Patent number: 6514755
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: February 4, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Mosely-Alldredge, Kellie A. Benzow
  • SCA7 gene and method of use
    Patent number: 6280938
    Abstract: The present invention provides diagnostic methods of identifying individuals at risk and not at risk of developing spinocerebellar ataxia type 7. The present invention also provides for methods for identifying expanded repeats, and the DNA flanking the expanded repeats, from genomic DNA.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: August 28, 2001
    Assignee: Regents of the University of Minnesota
    Inventors: Laura P. W. Ranum, Michael D. Koob, Melinda L. Moseley-Alldredge, Kellie A. Benzow