Patents by Inventor Michael D Leach
Michael D Leach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240075196Abstract: Apparatus and methods for extracellular vesicle enrichment are described in which apparatus may be used to create plasma preparations that are enriched in EV-containing fluid sample. Generally, one variation of a method may generally comprise contacting the fluid sample with a plurality of absorbent chromatographic beads to concentrate EVs from the fluid sample, and separating the beads from the fluid sample.Type: ApplicationFiled: June 2, 2023Publication date: March 7, 2024Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Publication number: 20240050695Abstract: Float securement apparatus and methods are described herein. One method of securing a float within a container may generally comprise positioning a float into a bottom of a container, introducing a volume of fluid within the bottom of the container such that the fluid covers the float, and forming a vapor lock between the float and the container such that a position of the float is secured relative to an interior of the container.Type: ApplicationFiled: May 19, 2023Publication date: February 15, 2024Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Publication number: 20230277747Abstract: Apparatus and methods for point-of-care red blood cell washing are disclosed. One method of filtering a suspension of red blood cells may generally comprise introducing a wash solution to the suspension of red blood cells such that a combined volume is retained within a first compartment, applying a sweeping action upon the volume, applying a pressure upon the volume while applying the sweeping action such that the volume is urged through a filter membrane at a predetermined filtration rate, maintaining the filtration rate over a predetermined period of time such that hemolysis is maintained below a threshold level, and collecting the volume within a second compartment.Type: ApplicationFiled: March 1, 2023Publication date: September 7, 2023Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Publication number: 20230263947Abstract: Apparatus and methods for concentrating platelet-rich plasma is described herein. One variation may generally comprise a tube having a length and defining a channel within and one or more ports located at a proximal end of the tube and in fluid communication with the channel. A plunger may slidably translatable within the channel while forming a seal against an inner surface of the channel and a float may have a pre-selected density and defining a concave interface surface, wherein the float is slidably contained within the channel such that the concave interface surface is in apposition to the one or more ports.Type: ApplicationFiled: May 2, 2023Publication date: August 24, 2023Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Patent number: 11672892Abstract: Apparatus and methods for concentrating platelet-rich plasma is described herein. One variation may generally comprise a tube having a length and defining a channel within and one or more ports located at a proximal end of the tube and in fluid communication with the channel. A plunger may slidably translatable within the channel while forming a seal against an inner surface of the channel and a float may have a pre-selected density and defining a concave interface surface, wherein the float is slidably contained within the channel such that the concave interface surface is in apposition to the one or more ports.Type: GrantFiled: December 27, 2022Date of Patent: June 13, 2023Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Publication number: 20230134453Abstract: Apparatus and methods for concentrating platelet-rich plasma is described herein. One variation may generally comprise a tube having a length and defining a channel within and one or more ports located at a proximal end of the tube and in fluid communication with the channel. A plunger may slidably translatable within the channel while forming a seal against an inner surface of the channel and a float may have a pre-selected density and defining a concave interface surface, wherein the float is slidably contained within the channel such that the concave interface surface is in apposition to the one or more ports.Type: ApplicationFiled: December 27, 2022Publication date: May 4, 2023Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Patent number: 11559613Abstract: Apparatus and methods for concentrating platelet-rich plasma is described herein. One variation may generally comprise a tube having a length and defining a channel within and one or more ports located at a proximal end of the tube and in fluid communication with the channel. A plunger may slidably translatable within the channel while forming a seal against an inner surface of the channel and a float may have a pre-selected density and defining a concave interface surface, wherein the float is slidably contained within the channel such that the concave interface surface is in apposition to the one or more ports.Type: GrantFiled: January 27, 2020Date of Patent: January 24, 2023Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Publication number: 20230001408Abstract: Apparatus and methods for separating blood components are disclosed in which an apparatus for separating blood generally includes a tube defining a channel and configured for receiving a quantity of blood and a float contained within the tube and having a density which is predefined so that the float is maintained at equilibrium between a first layer formed from a first fractional component of the blood and a second layer formed from a second fractional component of the blood. Upon completion of the centrifugation, the first layer may be removed from the tube while the float isolates the second layer from the first layer.Type: ApplicationFiled: September 2, 2022Publication date: January 5, 2023Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Patent number: 11541388Abstract: Apparatus and methods for separating blood components are disclosed in which an apparatus for separating blood generally includes a tube defining a channel and configured for receiving a quantity of blood and a float contained within the tube and having a density which is predefined so that the float is maintained at equilibrium between a first layer formed from a first fractional component of the blood and a second layer formed from a second fractional component of the blood. Upon completion of the centrifugation, the first layer may be removed from the tube while the float isolates the second layer from the first layer.Type: GrantFiled: May 27, 2021Date of Patent: January 3, 2023Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Patent number: 11534533Abstract: Apparatus and methods for processing blood are disclosed in which one variation generally comprises a tube defining a channel and an access tube extending into the channel. An open cell matrix configured to entrap red blood cells may be positioned within at least a portion of the channel. Another variation generally comprises a cylindrical tube and a plunger slidably positioned within the channel. The plunger also has a funnel positioned upon the plunger and is movable therewith. Both the plunger and funnel define a fluid channel through and in communication with the cylindrical tube.Type: GrantFiled: June 24, 2019Date of Patent: December 27, 2022Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Patent number: 11534534Abstract: Apparatus and methods for processing blood are disclosed in which one variation generally comprises a tube defining a channel and an access tube extending into the channel. An open cell matrix configured to entrap red blood cells may be positioned within at least a portion of the channel. Another variation generally comprises a cylindrical tube and a plunger slidably positioned within the channel. The plunger also has a funnel positioned upon the plunger and is movable therewith. Both the plunger and funnel define a fluid channel through and in communication with the cylindrical tube.Type: GrantFiled: March 18, 2020Date of Patent: December 27, 2022Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Patent number: 11478787Abstract: Apparatus and methods for separating blood components are disclosed in which an apparatus for separating blood generally includes a tube defining a channel and configured for receiving a quantity of blood and a float contained within the tube and having a density which is predefined so that the float is maintained at equilibrium between a first layer formed from a first fractional component of the blood and a second layer formed from a second fractional component of the blood. Upon completion of the centrifugation, the first layer may be removed from the tube while the float isolates the second layer from the first layer.Type: GrantFiled: June 27, 2019Date of Patent: October 25, 2022Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Publication number: 20210330873Abstract: Plasma/cell concentrator apparatus and methods are described herein for concentrating constituents from a fluid. Generally, a volume of the fluid may be urged from a first reservoir to a second reservoir through a fluid channel and a volume of desiccant for mixing with the fluid may be introduced to create a mixture. This fluid and desiccant mixture may be passed between the first and second reservoirs until one or more components from the fluid are absorbed by the desiccant. After mixing, the fluid may be withdrawn through a withdrawal channel which is in fluid communication with the fluid channel while preventing the desiccant from passing into the withdrawal channel.Type: ApplicationFiled: February 19, 2021Publication date: October 28, 2021Applicant: Hanuman Pelican, Inc,Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS
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Publication number: 20210283600Abstract: Apparatus and methods for separating blood components are disclosed in which an apparatus for separating blood generally includes a tube defining a channel and configured for receiving a quantity of blood and a float contained within the tube and having a density which is predefined so that the float is maintained at equilibrium between a first layer formed from a first fractional component of the blood and a second layer formed from a second fractional component of the blood. Upon completion of the centrifugation, the first layer may be removed from the tube while the float isolates the second layer from the first layer.Type: ApplicationFiled: May 27, 2021Publication date: September 16, 2021Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Publication number: 20210129132Abstract: In some forms, the present disclosure provides systems and methods for isolation of platelet rich plasma from a liquid tissue sample. In accordance with some forms of the disclosed systems and methods, provide rapid separation of blood components with the need for centrifugation. Accordingly, in one embodiment, the present disclosure provides a method for isolating platelet rich plasma, the method comprising combining a liquid tissue sample with a polymer composition, the polymer composition comprising polyethylene glycol.Type: ApplicationFiled: October 30, 2019Publication date: May 6, 2021Inventors: William King, Michael D. Leach
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Patent number: 10821218Abstract: Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can comprise a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface and a second surface opposite the first surface. The channel can extend along a longitudinal axis from a first end to a second end. The first acoustic wave generator can be coupled to the first surface. The first acoustic wave generator can be configured to generate an acoustic wave having a wavelength. The second acoustic wave propagating component can be coupled to the second surface. The second surface can be spaced an integer fractional multiple of the wavelength from the first surface and each integer factional multiple equals a number of pressure nodes within the channel.Type: GrantFiled: July 22, 2016Date of Patent: November 3, 2020Assignee: Biomet Biologics, LLCInventors: Randel E. Dorian, Richard Wood Storrs, Michael D. Leach, Ned M. Hamman, Joel Carne
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Patent number: 10737012Abstract: Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can include a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface, an opposing second surface, a first side, and an opposing second side. The channel can extend along a longitudinal axis from a first end to an opposing second end. The first acoustic wave generator can be coupled to the first surface. The second acoustic wave propagating component can be coupled to the second surface. The first acoustic wave generator and second acoustic wave propagating component can be configured to generate a bulk standing acoustic wave in the channel.Type: GrantFiled: July 22, 2016Date of Patent: August 11, 2020Assignee: Biomet Biologics, Inc.Inventors: Michael D. Leach, Ned M. Hamman, David Abeskaron, Grant Cunningham, Randel Dorian, Richard Wood Storrs, Scott R. King
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Publication number: 20200246516Abstract: Apparatus and methods for concentrating platelet-rich plasma is described herein. One variation may generally comprise a tube having a length and defining a channel within and one or more ports located at a proximal end of the tube and in fluid communication with the channel. A plunger may slidably translatable within the channel while forming a seal against an inner surface of the channel and a float may have a pre-selected density and defining a concave interface surface, wherein the float is slidably contained within the channel such that the concave interface surface is in apposition to the one or more ports.Type: ApplicationFiled: January 27, 2020Publication date: August 6, 2020Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING
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Patent number: 10729589Abstract: Oxygen diffusive wound dressings and methods of manufacturing and use are described herein. The wound dressing may generally provide a ready supply of oxygen to a wound being treated via one or more oxygen conduits which are designed to pass oxygen from ambient air or other oxygen reservoirs into proximity to the wound, and may also provide for exudate removal through transecting channels in fluid communication with both the wound surface and a hydrophilic absorbent material.Type: GrantFiled: February 13, 2017Date of Patent: August 4, 2020Assignee: Hanuman Pelican, Inc.Inventors: Randy Dorian, Richard W. Storrs, Michael D. Leach, Alexander B. Izvorski
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Publication number: 20200215243Abstract: Apparatus and methods for processing blood are disclosed in which one variation generally comprises a tube defining a channel and an access tube extending into the channel. An open cell matrix configured to entrap red blood cells may be positioned within at least a portion of the channel. Another variation generally comprises a cylindrical tube and a plunger slidably positioned within the channel. The plunger also has a funnel positioned upon the plunger and is movable therewith. Both the plunger and funnel define a fluid channel through and in communication with the cylindrical tube.Type: ApplicationFiled: March 18, 2020Publication date: July 9, 2020Applicant: Hanuman Pelican, Inc.Inventors: Randy DORIAN, Michael D. LEACH, Richard W. STORRS, Scott R. KING