Abstract: A method and apparatus for separation, concentration, and/or applying a biological or bio-engineered fluid. Generally, the fluid application device includes a sprayer body to enable the application of the fluid and a container adaptable to enable the separation of the fluid into at least a first component and a second component. The container is releasably coupled to the nozzle. The nozzle is adapted to withdraw at least one of the first component or the second component from the container after the fluid has been separated to apply the fluid to a selected site.

Abstract: A method and apparatus for obtaining various components of a multi-component material. Generally, a component of a whole blood sample may be concentrated from a patient and re-introduced to the same patient. For example, a clotting component, such as thrombin, from a whole blood sample may be extracted and concentrated in an apparatus and collection to be reapplied or reintroduced into a patient.

Abstract: An applicator for applying a multi-component bio-material including at least two containers. Both containers are held in a structure or oriented in a structure such that material contained in the containers can be expressed from oriented outlets simultaneously. The applicator includes a graspable member which allows the material to be expressed from all containers of the applicator substantially simultaneously. The applicator may be constructed such that a pre-selected and substantially different volume is expressed from each of the containers substantially simultaneously.