Abstract: Human scFvs are disclosed which interact with a conformational epitope along the pre-hairpin, N-helix coiled coil structure within the heptad repeat 1 (HR1) region of gp41 of HIV. These antibodies, as well as IgG conversions, are shown to neutralize diverse HIV isolates. Isolated nucleic acid molecules are also disclosed which encode relevant portions of these antibodies, as well as the purified forms of the expressed antibodies or relevant antibody fragments, such as VH and VL chains. The antibody compositions disclosed within this specification may provide for a therapeutic treatment against HIV infection by reducing viral load levels within an infected individual, thus prolonging the asymptomatic phase of HIV infection. These antibodies will also be useful in assays to identify HIV antiviral compounds as well as allowing for the identification of candidate HIV vaccines, such as HIV peptide vaccines.

Abstract: A fluid ejection device includes a first fire line adapted to conduct a first energy signal having energy pulses, a second fire line adapted to conduct a second energy signal having energy pulses, a first address generator configured to provide first address signals, a second address generator configured to provide second address signals, first drop generators and second drop generators. The first drop generators are electrically coupled to the first fire line and configured to respond to the first energy signal to eject fluid based on the first address signals. The second drop generators are electrically coupled to the second fire line and configured to respond to the second energy signal to eject fluid based on the second address signals.

Abstract: An optical target is provided. In one embodiment, the target is formed on a substrate. The target includes a first layer deposited below a second layer on the substrate. The second layer is deposited below a third layer on the substrate. The first layer has a topographic contour formed thereon, the first layer at least partially projecting a patterned topographical contour through the second layer to the third layer.

Abstract: A novel double haploid maize line designated PHWWD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing double haploid maize line PHWWD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHWWD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the double haploid line PHWWD or a trait conversion of PHWWD with another maize line. Inbred maize lines derived from double haploid maize line PHWWD, methods for producing other inbred maize lines derived from double haploid maize line PHWWD and the inbred maize lines and their parts derived by the use of those methods.

Abstract: Some embodiments of the present invention provide a system that tests a software program. During operation, the system creates a behavioral model of the software program using branches, decisions, and options. Next, the system applies a weight assignment technique to the behavioral model to create a set of global identifiers (IDs), which correspond to test cases of the behavioral model. The system then generates a test case from the behavioral model and executes the test case on the software program. Finally, the system analyzes an output of the executed test case to determine a validity of the software program.

Abstract: Some embodiments of the present invention provide a system that tests a software program. During operation, the system creates a behavioral model of the software program using branches, decisions, and options. Next, the system generates a test case from the behavioral model and executes the test case on the software program. Finally, the system analyzes an output of the executed test case to determine a validity of the software program.

Abstract: Systems, devices and methods transmit data from a patient device to a location, for example a remote location, where the patient is monitored. The system may comprise a server system, for example a backend server system, a gateway and the patient worn device. The gateway can be configured to communicate with the patient worn device in response to a list transmitted from the server, for example an approved patient device list transmitted from the server to the gateway. The gateway may exclude communication with patient worn devices that are not on the list. This use of the list can control data throughput from the patient device to the gateway and also from the gateway to the server, such that the communication from the device on the list to the server is maintained and appropriate information can be reliably sent from the patient device to the server.

Abstract: A fluid ejection device having a first fluid feed source having a first fluid feed source edge in communication with a substrate surface, first firing resistors disposed along the first fluid feed source and configured to respond to a first current to heat fluid provided by the first fluid feed source, and a reference conductor. The reference conductor is configured to conduct the first current from the first firing resistors, wherein the reference conductor is disposed between the first fluid feed source edge and the first firing resistors.

Abstract: Methods for producing homozygous plants, seeds, and plant cells are provided. Also provided are methods of transformation.

Abstract: A clamp includes a body, a lead pin moveable relative to the body and an actuator supported by the body. The actuator is axially moveable between an extended position and a retracted position. The actuator includes a camshaft drivingly coupled to the lead pin. Axial movement of the camshaft causes the lead pin to rotate between a first positioned aligned with a first longitudinal axis and a second position aligned with a second longitudinal axis laterally offset from the first longitudinal axis.

Abstract: A novel double haploid maize line designated PHWWD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing double haploid maize line PHWWD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHWWD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the double haploid line PHWWD or a trait conversion of PHWWD with another maize line. Inbred maize lines derived from double haploid maize line PHWWD, methods for producing other inbred maize lines derived from double haploid maize line PHWWD and the inbred maize lines and their parts derived by the use of those methods.

Abstract: The described embodiments relate to slotted substrates and methods of forming same. One exemplary method forms a first slot portion into a first surface of a substrate, the first slot portion defining a footprint at the first surface. The method also forms a second slot portion through the first slot portion; and, forms a third slot portion through a second surface of the substrate sufficiently to intercept the second slot portion to form a fluid-handling slot through the substrate.

Abstract: An optical target is provided. In one embodiment, the target is formed on a substrate. The target includes a first layer deposited below a second layer on the substrate. The second layer is deposited below a third layer on the substrate. The first layer has a topographic contour formed thereon, the first layer at least partially projecting a patterned topographical contour through the second layer to the third layer.

Abstract: A fluid ejection device comprises a first metal layer and a second metallayer. The first metal layer comprises an address path portion and a nonaddress path portion. The second metal layer, which overlies the first metal layer, comprises a first portion which comprises a power conducting portion. The power conducting portion is routed only over the non-address path portion of the first metal layer.