Patents by Inventor Michael Dappen

Michael Dappen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS
    Publication number: 20230074115
    Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.
    Type: Application
    Filed: August 4, 2022
    Publication date: March 9, 2023
    Inventors: Raissa TREND, Michael DAPPEN, Christopher E. HENRY, Adam Aaron GOLDBLUM, James Bradley AGGEN, Ricardo Filipe de Jesus Gonçalves MENDONÇA, João Carlos Falcão SARDINHA
  • Synthesis of antibacterial aminoglycoside analogs
    Patent number: 11453658
    Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: September 27, 2022
    Assignee: CIPLA USA, INC.
    Inventors: Raissa Trend, Michael Dappen, Christopher E. Henry, Adam Aaron Goldblum, James Bradley Aggen, Ricardo Filipe de Jesus Gonçalves Mendonça, João Carlos Falcão Sardinha
  • SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS
    Publication number: 20200317652
    Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.
    Type: Application
    Filed: April 16, 2020
    Publication date: October 8, 2020
    Inventors: Raissa TREND, Michael DAPPEN, Christopher E. HENRY, Adam Aaron GOLDBLUM, James Bradley AGGEN, Ricardo Filipe de Jesus Gonçalves MENDONÇA, João Carlos Falcão SARDINHA
  • N-Substituted Benzene Sulfonamides
    Publication number: 20070191341
    Abstract: Disclosed are N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. In Formula (I), R1, R2, R3, R4, R3?, R10 and R11 are as described herein. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders using compounds of Formula (I).
    Type: Application
    Filed: April 23, 2007
    Publication date: August 16, 2007
    Inventors: Martin Neitzel, Michael Dappen, Jennifer Marugg
  • Substituted n-phenyl sulfonamide bradykinin antagonists
    Publication number: 20070093485
    Abstract: Disclosed are certain substituted N-phenylsulfonamide derivatives and related compounds. These compounds are useful as bradykinin antagonists to relieve adverse symptoms in mammals mediated, at least in part, by bradykinin including pain, inflammation, bronchoconstriction, cerebral edema, etc.
    Type: Application
    Filed: December 18, 2003
    Publication date: April 26, 2007
    Inventors: Francine Farouz, Michael Dappen, Ying-Zi Xu, Sarah Bartulis, Ryan Holcomb, Ramesh Kasar, Michael Pleiss, Eugene Thorsett, Xiaocong Ye, Andrei Konradi
  • Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
    Publication number: 20070021555
    Abstract: Disclosed is a process for preparing polymer conjugates of agricultural, therapeutic, and food additive compounds using Mitsunobu conditions.
    Type: Application
    Filed: July 7, 2006
    Publication date: January 25, 2007
    Inventors: Andrei Konradi, Jenifer Smith, Michael Dappen, Christopher Semko
  • Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists
    Publication number: 20060293332
    Abstract: Disclosed are sulfonylquinoxalone acetamide derivatives useful as bradykinin antagonists.
    Type: Application
    Filed: May 5, 2006
    Publication date: December 28, 2006
    Inventors: Francine Grant, Sarah Bartulis, Louis Brogley, Michael Dappen, Ramesh Kasar, Mohammed Khan, Martin Neitzel, Michael Pleiss, Eugene Thorsett, John Tucker, Michael Ye, Jon Hawkinson
  • N-substituted benzene sulfonamides
    Publication number: 20050165003
    Abstract: Disclosed are N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. In Formula (I), R1, R2, R3, R4, R3?, R10 and R11 are as described herein. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders using compounds of Formula (I).
    Type: Application
    Filed: October 29, 2004
    Publication date: July 28, 2005
    Inventors: Martin Neitzel, Michael Dappen, Jennifer Marugg