Abstract: Various embodiments are described herein for a coil electrode, RF applicator and RF treatment apparatus, along with an associated method of operation, that have been developed for treating tumors in bone tissue, including large tumors with a single treatment session or ablating intravertebral nerves. Embodiments are also described that provide the capability to perform multifocal treatments for safe and effective treatment of multiple bone tumors or ablating intravertebral nerves. Embodiments are also described that provide a 3-tiered multi-modality treatment regimen which would sequentially include RF ablation of a bone tumor, tumor debulking and vertebroplasty or ablating intravertebral nerves as part of pain treatment.