Abstract: A method includes, under control of control circuitry implementing a mixing protocol, aspirating reagents from multiple different reagent reservoirs into a cache channel. Designated amounts of the reagents are automatically aspirated from the corresponding reagent reservoirs by corresponding sippers based on the mixing protocol implemented by the control circuitry. The method also includes discharging the reagents from the cache channel into a mixing reservoir, and mixing the reagents within the mixing reservoir to form a reagent mixture.

Abstract: The invention relates to methods for attaching therapeutic agents to structures produced by thermally induced phase separation as well as methods for coating devices and producing multi-layered microspheres.

Abstract: A method includes, under control of control circuitry implementing a mixing protocol, aspirating reagents from multiple different reagent reservoirs into a cache channel. Designated amounts of the reagents are automatically aspirated from the corresponding reagent reservoirs by corresponding sippers based on the mixing protocol implemented by the control circuitry. The method also includes discharging the reagents from the cache channel into a mixing reservoir, and mixing the reagents within the mixing reservoir to form a reagent mixture.

Abstract: An analysis system may perform operations on an analyte that may be combined with multiple regents prior to being introduced into a flow cell. The instrument may include a volume into which the reagents to be combined with the analyte are aspirated one-by-one. The volume may be formed as a serpentine channel in a valve manifold associated with sippers for aspirating the reagents. The reagents may then be mixed by cycling a pump to move the reagents within the mixing volume or channel.

Abstract: Various examples provide a printed circuit board (PCB) comprising a first route from a first through-hole via to a second through-hole via, and a second route from the second through-hole via to a first microvia (e.g., coupled to a second memory module socket). Additional microvias may have a route from the first microvia that effectively daisy chains the microvias from the second through-hold via. Various examples also provide a PCB comprising a first route from a first through-hole via to a second through-hole via, and a second route from the second through-hole via to a first sequential lamination via. Additional sequential lamination vias may have a route from the first microvia that effectively daisy chains the sequential lamination vias from the second through-hold via.

Abstract: An analysis system may perform operations on an analyte that may be combined with multiple regents prior to being introduced into a flow cell. The instrument may include a volume into which the reagents to be combined with the analyte are aspirated one-by-one. The volume may be formed as a serpentine channel in a valve manifold associated with sippers for aspirating the reagents. The reagents may then be mixed by cycling a pump to move the reagents within the mixing volume or channel. For this, the reagents may be aspirated from a recipient into the volume or channel, ejected back into the recipient, and this process may be performed repeatedly to enhance mixing.

Abstract: One exemplary embodiment is directed to a system comprising a switch used in a network and a central function configured to receive physical layer information related to the network. The physical layer information includes information associating media access control (MAC) addresses of devices on the network with ports of the switch. The switch is configured to use information about a spanning tree determined by the central function to configure the switch to carry out a switching function performed by the switch. The central function is configured to use at least some physical layer information about patching equipment in the network and end devices in the network in associating MAC addresses of devices on the network with the ports of the switch. Other embodiments are disclosed.

Abstract: Disclosed herein are devices and techniques for providing for enhanced fluid mixing in a sample vial. A plunger head may be removably housed inside of a cap that is attached to a container; the cap may have an opening allowing a shaft, e.g., a probe or sipper shaft, to be inserted into the cap and into the plunger head. The shaft may be used to push the plunger head free of the cap, and then to reciprocate the plunger head within the container to mix the content. Withdrawal of the shaft may then cause the plunger head to disengage from the shaft and remain in the container.

Abstract: The present invention relates to a composition for use in the treatment of a detached retina, comprising an oil and an additive capable of increasing the extensional viscosity of the oil. The present invention also relates to a method and kit of parts for producing the composition.

Abstract: In one embodiment, systems and methods for preventing messages from being redistributed are provided. A social-networking system may receive instructions from a user to create a messaging campaign. The instructions may include a blocking instruction. The system may identify a target user of the social-networking system to whom to present a message associated with the messaging campaign and present the message to the target user. The system may receive from the target user an input associated with the presented message. The input may be configured to cause the message to be presented to one or more other users connected to the target user within a threshold degree of separation in a social graph. In response to the input from the target user, the system may determine that the message is associated with the blocking instruction and prevent the message from being presented to the one or more other users.

Abstract: Disclosed herein are devices and techniques for providing for enhanced fluid mixing in a sample vial. A plunger head may be removably housed inside of a cap that is attached to a container; the cap may have an opening allowing a shaft, e.g., a probe or sipper shaft, to be inserted into the cap and into the plunger head. The shaft may be used to push the plunger head free of the cap, and then to reciprocate the plunger head within the container to mix the content. Withdrawal of the shaft may then cause the plunger head to disengage from the shaft and remain in the container.

Abstract: An analysis instrument may perform analytical operations on an analyte that is combined with multiple reagents prior to being introduced into a flow cell. The instrument may include a nozzle sipper that aspirates reagents from a recipient, along with an analyte. The reagents may be directed to a volume and may be repeatedly moved into and out of the volume by cycling of a pump. The reagents may be ejected into a destination recipient with the nozzle sipper promoting vorticity in the recipient to enhance mixing. The repeated aspiration and ejection through the nozzle sipper effectively mixes the reagents and the template in an automated or semi-automated fashion.

Abstract: An analysis system may perform operations on an analyte that may be combined with multiple regents prior to being introduced into a flow cell. The instrument may include a volume into which the reagents to be combined with the analyte are aspirated one-by-one. The volume may be formed as a serpentine channel in a valve manifold associated with sippers for aspirating the reagents. The reagents may then be mixed by cycling a pump to move the reagents within the mixing volume or channel.

Abstract: A method includes, under control of control circuitry implementing a mixing protocol, aspirating reagents from multiple different reagent reservoirs into a cache channel. Designated amounts of the reagents are automatically aspirated from the corresponding reagent reservoirs by corresponding sippers based on the mixing protocol implemented by the control circuitry. The method also includes discharging the reagents from the cache channel into a mixing reservoir, and mixing the reagents within the mixing reservoir to form a reagent mixture.

Abstract: A system and method for repairing corrupt software components of a computer system. Corrupt software is detected and repaired utilizing an automated component repair service. Repair files are downloaded from an external storage location and used to repair the corruption. The downloaded files are preferably the smallest amount of data necessary to repair the identified corruption. The process of repairing corrupt files is used in conjunction with a software updating service to resolve problems that occur when corrupt software is updated by allowing a corrupt component to be repaired and then uninstalled such that an updated component can be properly installed.