Patents by Inventor Michael Deeley

Michael Deeley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances and uses thereof
    Publication number: 20060057112
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding a novel macrophage-derived C-C chemokine designated “Macrophage Derived Chemokine” (MDC), and polypeptide fragments and analogs thereof. Also provided are materials and methods for the recombinant or synthetic production of the chemokine, fragments, and analogs; and purified and isolated chemokine protein, and polypeptide fragments and analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing. Also provided are assays for identifying modulators of MDC chemokine activity.
    Type: Application
    Filed: October 28, 2005
    Publication date: March 16, 2006
    Applicant: ICOS CORPORATION
    Inventors: Patrick Gray, David Chantry, Michael Deeley, Carol Raport, Ronald Godiska
  • Therapeutic uses for MDC and MDC antagonists
    Publication number: 20050238647
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C—C chemokine designated Macrophage Derived Chemokine (MDC), and polypeptide analogs thereof. Also provided are materials and methods for the recombinant production of the chemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing.
    Type: Application
    Filed: April 6, 2004
    Publication date: October 27, 2005
    Applicant: ICOS CORPORATION
    Inventors: Patrick Gray, David Chantry, Michael Deeley
  • DNA sequence encoding nonglycosylated analogs of human colony stimulating factors
    Patent number: 5405952
    Abstract: An analog human colony stimulating factor (hCSF) is disclosed, comprising a mutant amino acid sequence which is substantially homologous to the native sequence of an hCSF having at least one N-glycosylation site, wherein the mutant sequence comprises at least one amino acid substitution, deletion or insertion inactivating the N-glycosylation site.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: April 11, 1995
    Assignee: Immunex Corporation
    Inventors: Michael Deeley, Virginia L. Price, David Urdal
  • Nonglycosylated analogs of human colony stimulating factors
    Patent number: 5032676
    Abstract: An analog human colony stimulating factor (hCSF) is disclosed, comprising a mutant amino acid sequence which is substantially homologous to the native sequence of an hCSF having at least one N-glycosylation site, wherein the mutant sequence comprises at least one amino acid substitution, deletion or insertion inactivating the N-glycosylation site.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: July 16, 1991
    Assignee: Immunex Corporation
    Inventors: Michael Deeley, Virginia L. Price, David Urdal