Patents by Inventor Michael Degraffenreid

Michael Degraffenreid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzamide derivatives and uses related thereto
    Patent number: 8772296
    Abstract: Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: July 8, 2014
    Assignee: Amgen Inc.
    Inventors: Jay P. Powers, Michael Degraffenreid, Lisa Julian, Jacob Kaizerman, Dustin McMinn, Yosup Rew, Daqing Sun, Xuelei Yan, Zhulun Wang, Felix Gonzalez Lopez De Turiso
  • BENZAMIDE DERIVATIVES AND USES RELATED THERETO
    Publication number: 20100069447
    Abstract: Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.
    Type: Application
    Filed: October 20, 2009
    Publication date: March 18, 2010
    Inventors: Jay P. POWERS, Michael Degraffenreid, Xiao He, Lisa Julian, Dustin L. McMinn, Daqing Sun, Yosup Rew, Xuelei Yan
  • Benzamide derivatives and uses related thereto
    Patent number: 7605289
    Abstract: Benzamide derivatives of formula I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: October 20, 2009
    Assignee: Amgen, Inc.
    Inventors: Jay P. Powers, Michael Degraffenreid, Xiao He, Lisa Julian, Dustin L. McMinn, Daqing Sun, Yosup Rew, Xuelei Yan
  • Benzamide derivatives and uses related thereto
    Publication number: 20070299080
    Abstract: Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein.
    Type: Application
    Filed: May 31, 2007
    Publication date: December 27, 2007
    Inventors: Jay Powers, Michael Degraffenreid, Lisa Julian, Jacob Kaizerman, Dustin McMinn, Yosup Rew, Daqing Sun, Xuelei Yan, Zhulun Wang
  • Benzamide derivatives and uses related thereto
    Publication number: 20060293392
    Abstract: Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.
    Type: Application
    Filed: June 8, 2006
    Publication date: December 28, 2006
    Inventors: Jay Powers, Michael Degraffenreid, Xiao He, Lisa Julian, Dustin McMinn, Daqing Sun, Yosup Rew, Xuelei Yan
  • Arylsulfonamides and uses related thereto
    Publication number: 20050288271
    Abstract: Arylsulfonamide compounds of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:
    Type: Application
    Filed: April 20, 2005
    Publication date: December 29, 2005
    Applicant: Amgen Inc.
    Inventors: Michael DeGraffenreid, Jay Powers, Daqing Sun, Xuelei Yan
  • Aryl sulfonamide compounds and uses related thereto
    Publication number: 20050277649
    Abstract: The present invention provides Aryl Sulfonamide Compounds having the formula: and prodrugs or pharmaceutically acceptable salts or prodrugs thereof. The Aryl Sulfonamide Compounds are useful for treating diabetes, obesity, and other diseases and disorders.
    Type: Application
    Filed: December 20, 2004
    Publication date: December 15, 2005
    Applicants: Amgen SF, LLC, Japan Tobacco, Inc.
    Inventors: Michael DeGraffenreid, Xiao He, Jay Powers, Daqing Sun, Xuelei Yan