Patents by Inventor Michael Dho Spangfort

Michael Dho Spangfort has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant allergens
    Publication number: 20040091500
    Abstract: Novel recombinant allergens are disclosed. The allergens are non-naturally occurring mutants derived from naturally-occurring allergens. The overall &agr;-carbon backbone tertiary structure of the allergens is essentially preserved. Also disclosed are methods for preparing the recombinant allergens as well as the use of the recombinant allergens for the treatment of allergic reactions.
    Type: Application
    Filed: November 20, 2003
    Publication date: May 13, 2004
    Applicant: ALK-Abello A/S
    Inventors: Hans Henrik Ipsen, Michael Dho Spangfort, Jorgen Nedergaard Larsen
  • Novel mutant allergens
    Publication number: 20030175312
    Abstract: Novel recombinant allergens with multiple mutations and reduced IgE binding affinity are disclosed. The allergens are non-naturally occurring mutants of naturally-occurring allergens. The overall &agr;-carbon backbone tertiary structure is essentially preserved. Also disclosed is a method for preparing such recombinant allergens as well as uses thereof.
    Type: Application
    Filed: November 15, 2001
    Publication date: September 18, 2003
    Applicant: ALK-Abello A/S
    Inventors: Jens Holm, Hans Henrik Ipsen, Jorgen Nedergaard Larsen, Michael Dho Spangfort
  • Recombinant hybrid allergen constructs with reduced allergenicity that retain immunogenicity of the natural allergen
    Publication number: 20030039660
    Abstract: Disclosed are recombinant hybrid proteins having at least one antigenic peptide sequence introduced into a scaffold protein that retain a native conformation. Also disclosed are recombinant nucleic acids and vectors encoding the hybrid proteins. The hybrid proteins retain immunogenicity but exhibit reduced allergenicity. The hybrid proteins are therefore particularly useful for therapeutic treatment of allergy.
    Type: Application
    Filed: March 4, 2002
    Publication date: February 27, 2003
    Applicant: The Rockefeller University
    Inventors: Te Piao King, Michael Dho Spangfort