Patents by Inventor Michael Diebold
Michael Diebold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240016429Abstract: The invention is related to a hand-operated actuator mechanism for driving a piercing element with increased safety. The actuator mechanism comprises a mounting element connected to a trigger element by a first breakable connection element. It also comprises a piercing element carrier connected to the trigger element by a second breakable connection element. The trigger element further comprises a pushing member that can be pushed with a human finger. The first breakable connection element is configured to be broken by means of a predetermined pushing finger force pushing said pushing member. The piercing element carrier being movable between an initial position wherein the first and the second breakable connection elements are unbroken, and a stop position wherein an abutment stops a movement of the piercing element carrier.Type: ApplicationFiled: October 29, 2021Publication date: January 18, 2024Inventors: Elif KÜCÜKTAS, Michael DIEBOLD, Markus RIESTER
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Publication number: 20230383338Abstract: The present invention relates to a fast and optionally multiplexing or multimeric method for isothermal amplification of nucleic acids, including DNA and RNA. Particularly, the invention relates to diagnostic methods for rapidly diagnosing, for example, at least two infectious agents, or at least two different targets in the same infectious agent, in a biological probe of interest. The invention further relates to a handheld and portable diagnostic system for performing the amplification method in a laboratory as well as in a non-laboratory environment. Further provided are suitable enzyme sequences, kits and uses of the method and the system.Type: ApplicationFiled: September 30, 2021Publication date: November 30, 2023Inventors: Markus RIESTER, Michael DIEBOLD, Manfred WEIDMANN, Anke KURRECK, Ulf THIELE
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Publication number: 20230167483Abstract: The invention relates to a system is provided that comprises a lysis chamber, an amplification chamber and a fluorescence detection device. The fluorescence detection device (16) comprises - a detection chamber (42) configured to receive the amplification chamber (14) or the contents of the amplification chamber, - a light source (44), - an optical sensor (46), - energy supply means (48), - a wireless data interface (52) and - a controller (50).Type: ApplicationFiled: April 7, 2021Publication date: June 1, 2023Inventors: Markus RIESTER, Michael DIEBOLD
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Patent number: 11662345Abstract: A testing assembly for lateral flow assay comprising a liquid sample receiving unit arranged on a support structure defining a plane and configured to receive a liquid sample via the liquid sample receiving interface, at least one testing strip having, in a planar state, a testing strip center line length (L) in a longitudinal direction, a testing strip width in a width direction and a testing strip thickness, and comprising a capillary wick that includes a test portion that comprises a reacting material configured to react in a predetermined manner to a pre-specified analyte, wherein the width direction of the testing strip extends at an angle smaller than 90° with respect to a normal of the plane, and wherein the testing strip is curved, resulting in an effective extension being shorter than the testing strip center line length in the planar state.Type: GrantFiled: January 23, 2019Date of Patent: May 30, 2023Assignee: HOMEDICUS GMBHInventors: Markus Riester, Michael Diebold, Jörn Bungartz
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Publication number: 20230158492Abstract: The invention relates to a system is provided that comprises a first container, a second container and a fluorescence detection device. The first container comprises a first set of chemicals and/or agents and is closed prior to use. The second container comprises a second set of chemicals and/or agents that are at least in part distinct from the chemicals and/or agents of the first set. The first container comprises a lid, that can be opened when the first container and the second container are combined to form a single, fluid tight assembly, in order to allow the contents of the first container to enter the second container.Type: ApplicationFiled: April 7, 2021Publication date: May 25, 2023Inventors: Markus RIESTER, Michael DIEBOLD
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Publication number: 20230070729Abstract: The invention relates to a testing device with a testing assembly for lateral flow assay. The testing assembly comprises liquid sample receiving interface arranged on a support structure defining a plane. The liquid sample receiving interface is configured to receive a liquid sample. The testing assembly comprises at least one testing strip fluidly connected to the liquid sample receiving interface. The testing strip comprises a capillary wick fluidly connected to the liquid sample receiving interface and including at least one test portion, the test portion comprising at least one respective reacting material configured for reacting in a predetermined manner to at least one specific analyte. The testing device comprises an optical sensor, arranged and configured for detecting light reflected from the at least one test portion and for converting the detected light into an electrical signal representing an intensity and/or a color of the detected light.Type: ApplicationFiled: February 1, 2021Publication date: March 9, 2023Inventors: Markus RIESTER, Michael DIEBOLD
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Publication number: 20230023058Abstract: The invention relates to a system which, on the one hand, has a classifier that is formed by a discriminative neural network and that implements a binary class model or a multi-class model. On the other hand, the system has a model-based sample generator that is formed by a generative neural network. Both the classifier and the model-based sample generator are trained—for a corresponding class—with the same training data records and therefore embody models that correspond to one another for this class. The invention also relates to a method for determining a quality criterion for input data records for a classifier with a discriminative neural network. The classifier has been trained with training data records and represents a classification model for a class. According to the method, a model-based sample generator with a generative neural network is initially provided and trained with the same training data records that were used to train the classifier.Type: ApplicationFiled: December 23, 2020Publication date: January 26, 2023Inventors: Sebastian NIEHAUS, Michael DIEBOLD, Janis REINELT, Daniel LICHTERFELD
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Publication number: 20220207285Abstract: The invention relates to a classifier system for classifying states of a system that is characterized by measurable system parameters, or for classifying objects, which classifier system has a plurality of decentralized, i.e. local, classifier units and a central classifier unit. The decentralized classifier units can be clients, for example, and the central classifier unit can be a server in a client-server system. In this type of system, the decentralized classifier units are formed (trained) in a decentralized manner and subsequently combined centrally to form binary classifier units which, in turn, can form a multiclass classifier unit.Type: ApplicationFiled: May 11, 2020Publication date: June 30, 2022Inventors: Sebastian NIEHAUS, Michael DIEBOLD, Daniel LICHTERFELD
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Patent number: 11147485Abstract: A device for extracting a body fluid and testing a predetermined analyte or property of the fluid is provided. The device comprises a hollow needle having a channel linking a base end and a tip, a collection chamber having an input end in fluid communication with the channel, a testing chamber, a solution chamber and a flow control. The collection chamber comprises a capillary wick configured to transport at least a fraction of the body fluid away from the input end. The testing chamber comprises a testing unit including a reacting material configured to react to a predetermined analyte or property of the fluid and the solution chamber comprises a buffer solution. A flow control is also provided for a transfer of the buffer solution from the solution chamber to the collection chamber and a transfer of the body fluid from the collection chamber to the testing chamber.Type: GrantFiled: May 3, 2017Date of Patent: October 19, 2021Inventors: Michael Diebold, Markus Riester, Jorn Bungartz
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Publication number: 20200346209Abstract: A testing assembly for lateral flow assay comprising a liquid sample receiving unit arranged on a support structure defining a plane and configured to receive a liquid sample via the liquid sample receiving interface, at least one testing strip having, in a planar state, a testing strip center line length (L) in a longitudinal direction, a testing strip width in a width direction and a testing strip thickness, and comprising a capillary wick that includes a test portion that comprises a reacting material configured to react in a predetermined manner to a pre-specified analyte, wherein the width direction of the testing strip extends at an angle smaller than 90° with respect to a normal of the plane, and wherein the testing strip is curved, resulting in an effective extension being shorter than the testing strip center line length in the planar state.Type: ApplicationFiled: January 23, 2019Publication date: November 5, 2020Inventors: Markus RIESTER, Michael DIEBOLD, Jörn BUNGARTZ
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Publication number: 20190142318Abstract: A body fluid extraction device for extracting a body fluid and for testing a predetermined analyte or property of the fluid comprises a hollow needle having a channel linking a base end and a tip in fluid communication, a collection chamber having an input end in fluid communication with the channel, the collection chamber comprising a capillary wick configured to transport at least a fraction of the body fluid away from the input end, a testing chamber comprising a testing unit that includes a reacting material configured to react to a predetermined analyte or property of the body fluid, a solution chamber, comprising a buffer solution and flow control means configured to control, a first transfer of the buffer solution from the solution chamber to the collection chamber, and a second transfer of the body fluid from the collection chamber to the testing chamber.Type: ApplicationFiled: May 3, 2017Publication date: May 16, 2019Inventors: Michael DIEBOLD, Markus RIESTER, Jorn BUNGARTZ
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Patent number: 10258283Abstract: Embodiments include an implant for insertion into a human and/or animal body and an insertion device for the implant. The implant includes a housing, at least one negative pressure unit and at least one adhesive application unit to temporarily and/or permanently fix the implant to a bodily tissue.Type: GrantFiled: July 17, 2015Date of Patent: April 16, 2019Assignee: Biotronik SE & Co. KGInventors: Thomas Doerr, Michael Diebold
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Patent number: 9827414Abstract: Embodiments include a medical implant for insertion into the human and/or animal body. The medical implant includes a helical fixing device to fix the implant at a site of implantation, wherein the helical fixing device is one or more of coupled to a locking device on the fixing device and coupled to an implant surface. One or more of the locking device and the implant surface impedes an autonomous detachment of the fixing device.Type: GrantFiled: July 17, 2015Date of Patent: November 28, 2017Assignee: BIOTRONIK SE & CO. KGInventors: Thomas Doerr, Michael Diebold
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Patent number: 9827429Abstract: A medical implant including an implant body for insertion into a human and/or animal body. The implant body includes at least one first and at least one second contact portion, wherein the at least one first and the at least one second contact portions contact two tissue regions performing a relative movement with respect to one another. The at least one first and the at least one second contact portions are movable relative to one another, wherein a relative movement of the contact portions may be converted into an electrical signal.Type: GrantFiled: July 17, 2015Date of Patent: November 28, 2017Assignee: Biotronik SE & Co. KGInventors: Thomas Doerr, Michael Diebold
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Patent number: 9770586Abstract: Embodiments include a medical implant including a fixing device with at least one fixing element to fix the implant at a site of implantation. The implant includes a belt drive that rotates an actuation device, wherein the actuation device is coupled to the fixing device and converts the rotary movement into a longitudinal movement of the fixing device. Embodiments include an insertion device to insert the medical implant.Type: GrantFiled: July 17, 2015Date of Patent: September 26, 2017Assignee: Biotronik SE & Co. KGInventors: Thomas Doerr, Michael Diebold
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Publication number: 20160144193Abstract: Embodiments include a medical implant that is inserted into a human and/or animal body. The medical implant includes an energy source, a pulse generator, a control unit and at least one electrode pair that delivers electrical stimulation pulses to a bodily tissue. Embodiments include a sensor, provided on an implant side of the medical implant, that identifies an implant-external trigger element. The control unit is coupled to the sensor and may be activated depending on a sensor signal of the sensor to perform an adaptation sequence of stimulation parameters, in which test stimulation pulses may be outputted. Embodiments include a method of setting a parameter set of therapeutic electrical stimulation pulses of a medical implant.Type: ApplicationFiled: October 12, 2015Publication date: May 26, 2016Applicant: BIOTRONIK SE & CO. KGInventors: Thomas DOERR, Michael DIEBOLD
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Patent number: 9314189Abstract: An extracorporeal physiological measurement device is disclosed, having fastening means for attaching to the body of a person or animal, measurement means for detection of values of a physiological measured variable on the body, and movement-detecting means and measured-value-influencing means connected thereto at the input for influencing the detected measured values before processing or storage as a function of a position or movement status of the body or the measurement device detected by the detection means such that the measured-value-influencing means have a unit for detection of a shift in position between the measurement device and the body.Type: GrantFiled: November 4, 2010Date of Patent: April 19, 2016Assignee: Biotronik CRM Patent AGInventors: Michael Diebold, Jens Philipp
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Publication number: 20160051194Abstract: Embodiments include an implant for insertion into a human and/or animal body and an insertion device for the implant. The implant includes a housing, at least one negative pressure unit and at least one adhesive application unit to temporarily and/or permanently fix the implant to a bodily tissue.Type: ApplicationFiled: July 17, 2015Publication date: February 25, 2016Applicant: Biotronik SE & Co. KGInventors: Thomas DOERR, Michael DIEBOLD
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Publication number: 20160051811Abstract: Embodiments include a medical implant for insertion into the human and/or animal body. The medical implant includes a helical fixing device to fix the implant at a site of implantation, wherein the helical fixing device is one or more of coupled to a locking device on the fixing device and coupled to an implant surface. One or more of the locking device and the implant surface impedes an autonomous detachment of the fixing device.Type: ApplicationFiled: July 17, 2015Publication date: February 25, 2016Applicant: BIOTRONIK SE & CO. KGInventors: Thomas DOERR, Michael DIEBOLD
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Publication number: 20160051810Abstract: Embodiments include a medical implant including a fixing device with at least one fixing element to fix the implant at a site of implantation (310). The implant includes a belt drive that rotates an actuation device, wherein the actuation device is coupled to the fixing device and converts the rotary movement into a longitudinal movement of the fixing device. Embodiments include an insertion device to insert the medical implant.Type: ApplicationFiled: July 17, 2015Publication date: February 25, 2016Applicant: Biotronik SE & Co. KGInventors: Thomas DOERR, Michael DIEBOLD