Patents by Inventor Michael Doherty
Michael Doherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12233356Abstract: The present disclosure relates to multistep chromatographic methods for preparing extracellular vesicles (EVs). The methods were demonstrated to be effective in preparing highquality EVs in a large scale. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use.Type: GrantFiled: March 20, 2020Date of Patent: February 25, 2025Assignee: LONZA SALES AGInventors: Aaron Noyes, Michael Doherty, Kimberly Ellis, Raymond Bourdeau, Kayla Desanty
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Publication number: 20240375684Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a pull-over location using machine learning. One of the methods includes obtaining data specifying a target pull-over location for an autonomous vehicle travelling on a roadway. A plurality of candidate pull-over locations in a vicinity of the target pull-over location are identified. For each candidate pull-over location, an input that includes features of the candidate pull-over location is processed using a machine learning model to generate a respective likelihood score representing a predicted likelihood that the candidate pull-over location is an optimal location. The features of the candidate pull-over location include one or more features that compare the candidate pull-over location to the target pull-over location. Using the respective likelihood scores, one of the candidate pull-over locations is selected as an actual pull-over location for the autonomous vehicle.Type: ApplicationFiled: July 25, 2024Publication date: November 14, 2024Inventors: Jonathan Lee Pedersen, Yu Zheng, Eamonn Michael Doherty, Brian Clair Williammee, Kevin Joseph Malta, Chung Eun Kim, Xu Dong
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Publication number: 20240294804Abstract: A method of bonding first and second substrates to each other the substrates having respective bonding surfaces to be bonded together, comprising: (a) applying to the bonding surface of at least the first substrate a redox-active metal catalyst primer to form a primed surface; (b) activating the primed bonding surface of the first substrate by exposing the primed bonding surface to actinic radiation; (c) applying, to the so activated bonding surface of the first substrate, and/or or to the bonding surface of the second substrate, a UV curable anaerobic adhesive; (d) mating the bonding surfaces together with the UV curable anaerobic adhesive therebetween; and (e) exposing the UV curable anaerobic adhesive between the mated surfaces to actinic UV radiation. The method is particularly suited for obtaining bonds with good tensile shear strength with electrical substrates coated with an insulating varnish.Type: ApplicationFiled: March 14, 2024Publication date: September 5, 2024Inventors: Michael Doherty, Brian Deegan, Stephen Fearon, David Condron, Barry Burns
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Patent number: 12071162Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a pull-over location using machine learning. One of the methods includes obtaining data specifying a target pull-over location for an autonomous vehicle travelling on a roadway. A plurality of candidate pull-over locations in a vicinity of the target pull-over location are identified. For each candidate pull-over location, an input that includes features of the candidate pull-over location is processed using a machine learning model to generate a respective likelihood score representing a predicted likelihood that the candidate pull-over location is an optimal location. The features of the candidate pull-over location include one or more features that compare the candidate pull-over location to the target pull-over location. Using the respective likelihood scores, one of the candidate pull-over locations is selected as an actual pull-over location for the autonomous vehicle.Type: GrantFiled: September 30, 2021Date of Patent: August 27, 2024Assignee: Waymo LLCInventors: Jonathan Lee Pedersen, Yu Zheng, Eamonn Michael Doherty, Brian Clair Williammee, Kevin Joseph Malta, Chung Eun Kim, Xu Dong
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Publication number: 20240052219Abstract: An anaerobically curable composition comprising: a liquid anaerobically curable component; a solid anaerobically curable component; a solid polyether thermoplastic polyurethane resin; and a curing component for curing the anaerobically curable components. Advantageously, the compositions of the invention are substantially solid and may be used as threadlockers.Type: ApplicationFiled: October 19, 2023Publication date: February 15, 2024Inventors: Gavin Haberlin, Michael Doherty, Nigel Sweeney, Rory Barnes, David Condron, Barry Burns
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Publication number: 20230312800Abstract: The present invention relates to a curable composition comprising a curable cyanoacrylate component and at least one thermoplastic polyurethane (TPU) component. The compositions of the invention are non-flowable at room temperature (25° C.) and are suitable for use as adhesive compositions, for example in a tape form.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Inventors: Rory Barnes, Michael Doherty, Nigel Sweeney, Ciara Goff
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Publication number: 20230220254Abstract: A sealant material for sealing joints between male and female mating parts comprising: (a) an elongate flexible thread suitable for wrapping around at least one of the parts, and (b) a joint sealing composition comprising an anaerobically curable composition in solid form, the flexible thread being coated with the anaerobically curable composition. This provides a reactive composition on the thread for sealing joints.Type: ApplicationFiled: March 22, 2023Publication date: July 13, 2023Inventors: Deirdre Ledwith, Laura Vaissaud, Michael Doherty, James Houlihan, Brendan Kneafsey
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Publication number: 20230113686Abstract: An anaerobically curable composition comprising: a liquid anaerobically curable component; a solid anaerobically curable component; a solid thermoplastic polyurethane resin having a molecular weight in the range of from 40,000 g/mol to 100,000 g/mol and a melting point in the range of from 40° C. to 80° C.; and a curing component for curing the anaerobically curable components. Advantageously, the compositions of the invention are substantially solid and may be used as threadlockers.Type: ApplicationFiled: October 3, 2022Publication date: April 13, 2023Inventors: Nigel Sweeney, Brendan Kneafsey, Rory Barnes, Michael Doherty, James Anthony Houlihan
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Patent number: 11618841Abstract: A sealant material for sealing joints between male and female mating parts comprising: (a) an elongate flexible thread suitable for wrapping around at least one of the parts, and (b) a joint sealing composition comprising an anaerobically curable composition in solid form, the flexible thread being coated with the anaerobically curable composition. This provides a reactive composition on the thread for sealing joints.Type: GrantFiled: April 17, 2019Date of Patent: April 4, 2023Assignee: Henkel AG & Co. KGaAInventors: Deirdre Ledwith, Laura Vaissaud, Michael Doherty, James Houlihan, Brendan Kneafsey
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Publication number: 20230099334Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a pull-over location using machine learning. One of the methods includes obtaining data specifying a target pull-over location for an autonomous vehicle travelling on a roadway. A plurality of candidate pull-over locations in a vicinity of the target pull-over location are identified. For each candidate pull-over location, an input that includes features of the candidate pull-over location is processed using a machine learning model to generate a respective likelihood score representing a predicted likelihood that the candidate pull-over location is an optimal location. The features of the candidate pull-over location include one or more features that compare the candidate pull-over location to the target pull-over location. Using the respective likelihood scores, one of the candidate pull-over locations is selected as an actual pull-over location for the autonomous vehicle.Type: ApplicationFiled: September 30, 2021Publication date: March 30, 2023Inventors: Jonathan Lee Pedersen, Yu Zheng, Eamonn Michael Doherty, Brian Clair Williammee, Kevin Joseph Malta, Chung Eun Kim, Xu Dong
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Patent number: 11612573Abstract: The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.Type: GrantFiled: September 30, 2019Date of Patent: March 28, 2023Assignee: DERMAVANT SCIENCES GMBHInventors: Sujatha D. Sonti, Joey Roger Thomas, Jon Lenn, Leandro Santos, Justin Whiteman, Michael Doherty, Mary Bedard, Piyush Jain
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Patent number: 11357824Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.Type: GrantFiled: March 16, 2020Date of Patent: June 14, 2022Assignee: Axcella Health Inc.Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
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Patent number: 11325335Abstract: Disclosed herein is a method and apparatus for forming pellets in a non-ambient environment such as a strong magnetic field. The apparatus includes a die body, a die bottom, a short push pin, a long push pin, a press tube, and an extended push pin. A powder is loaded into the die body, which is then positioned in the non-ambient environment, and the powder allowed to equilibrate. A pellet is then formed by pressing on the extended push pin while the powder is in the non-ambient environment.Type: GrantFiled: August 7, 2019Date of Patent: May 10, 2022Assignee: The Government of the United States of America, as represented by the Secretarv of the NavyInventors: Scooter David Johnson, Jeffrey Wang Xing, Michael Doherty
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Patent number: 11316940Abstract: A system, method, and computer-readable medium for identifying music-related data based on message data from a messaging platform. The method includes: obtaining a request from a client; identifying context data associated with the request; identifying message data from the messaging platform based on the context data; selecting, based on the context data and the message data from the messaging platform, music-related data for inclusion in a result set; and providing the result set to the client in response to the request.Type: GrantFiled: May 5, 2020Date of Patent: April 26, 2022Assignee: Twitter, Inc.Inventors: Stephen G. Phillips, Michael Doherty
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Publication number: 20220073784Abstract: A curative free sealant composition for sealing joints between male and female parts, the sealant composition comprising a solid resin component, a solid (meth)acrylate polyurethane component, and an ethoxylated bisphenol-A (meth)acrylate component.Type: ApplicationFiled: November 18, 2021Publication date: March 10, 2022Inventors: Michael Doherty, Nigel Sweeney, Brendan Kneafsey, David Condron, Frances Murphy
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Publication number: 20210171810Abstract: Benzoylthiourea or benzoylthiourethane derivatives in organohalides as carriers for primers for two step adhesive systems are provided.Type: ApplicationFiled: February 1, 2021Publication date: June 10, 2021Inventors: Nigel Sweeney, Darren Nolan, Brendan Kneafsey, Mark Loane, James Houlihan, Michael Doherty
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Publication number: 20210139623Abstract: The present invention relates to anaerobically curable compositions made from renewable materials. In particular, an alpha-methylene-lactone is used with a (meth)acrylate component and a cure system to form an anaerobically curable composition.Type: ApplicationFiled: January 20, 2021Publication date: May 13, 2021Inventors: Adrian Brandt, Horst Beck, Andreas Taden, Ralph Nemitz, Alexander Kux, Nigel Sweeney, David Birkett, Brendan Kneafsey, James Anthony Houlihan, Michael Doherty
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Publication number: 20200306342Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.Type: ApplicationFiled: March 16, 2020Publication date: October 1, 2020Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
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Publication number: 20200188481Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.Type: ApplicationFiled: September 27, 2019Publication date: June 18, 2020Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
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Patent number: 10686898Abstract: A system, method, and computer-readable medium for identifying music-related data based on message data from a messaging platform. The method includes: obtaining a request from a client; identifying context data associated with the request; identifying message data from the messaging platform based on the context data; selecting, based on the context data and the message data from the messaging platform, music-related data for inclusion in a result set; and providing the result set to the client in response to the request.Type: GrantFiled: March 17, 2014Date of Patent: June 16, 2020Assignee: Twitter, Inc.Inventors: Stephen G. Phillips, Michael Doherty