Abstract: Disclosed herein is a system for transferring brachytherapy elements to a needle, such as seeds, connectors, spacers, and strands. The system comprises a transfer device and, optionally, a stylet and a rack configured to hold one or more transfer devices.

Abstract: A brachytherapy seed comprising (a) carrier-free 103Pd isotope, (b) a substrate for the carrier-free 103Pd radioisotope, and (c) a casing for encapsulating the carrier-free 103Pd-laden substrate, is disclosed.

Abstract: Disclosed herein is a system for transferring brachytherapy elements to a needle, such as seeds, connectors, spacers, and strands. The system comprises a transfer device and, optionally, a stylet and a rack configured to hold one or more transfer devices.

Abstract: An apparatus in one example comprises a vial that comprises a vial bottom and a vial cap that connect to enclose one or more radioactive seeds; and a radiation shielding container that comprises a bottom portion and a top portion that connect to enclose the vial. The radiation shielding container and the vial comprise one or more vents for movement of a sterilant therethrough for sterilization of the one or more radioactive seeds within the vial. The bottom portion of the radiation shielding container comprises a structure that engages the vial bottom to prevent rotational movement of the vial bottom during removal of the vial cap.

Abstract: A delivery system for interstitial radiation therapy that uses a brachytherapy needle assembly for simultaneously dispensing an effective amount of medicine, such as anti-inflammatory agents, along with radioactive seeds. Medicine can be stored in and dispensed from a reservoir attached to a needle hub or to a stylet handle or it can be injected into the needle via a three-way fitting. Alternatively, medication can be added directly to the needle cannula. Additionally, the brachytherapy needle or the radioactive seeds and spacers can be coated with medication that would be absorbed by the body upon implantation.

Abstract: An applicator system for interstitial radiation therapy that uses a brachytherapy needle assembly for simultaneously dispensing an effective amount of medicine, such as anti-inflammatory agents, along with radioactive seeds. A medicine cartridge or a modified seed cartridge, having a reservoir on its proximal end, can be attached to the applicator body for dispensing medicine into a needle or medicine can be injected into the needle via a three-way fitting attached to the applicator body. Alternatively, a modified stylet having a reservoir on its proximal end containing medicine can be used to deliver medication to a needle. Additionally, the brachytherapy needle or the radioactive seeds and spacers can be coated with medication that would be absorbed by the body upon implantation.

Abstract: A brachytherapy seed comprising (a) carrier-free 103Pd isotope, (b) a substrate for the carrier-free 103Pd radioisotope, and (c) a casing for encapsulating the carrier-free 103Pd-laden substrate, is disclosed.

Abstract: An apparatus in one example comprises a radiation shielding container for one or more radioactive sources. One or more of the one or more radioactive sources are containable within one or more cartridges. The radiation shielding container comprises a support component that restrains movement within the radiation shielding container of one or more of the one or more cartridges. The radiation shielding container comprises one or more vents for movement of a sterilant therethrough.

Abstract: A method of forming a film laminate uses an adhesive composition containing at least three components A, B and C. The method includes providing a radiation curable adhesive that contains a) a compound bearing at least one epoxy group, b) a compound with at least three OH groups and a molecular weight below 400 and c) a photoinitiator which initiates a polymerization of components a) and b) after exposure to light with a wavelength of 100 to 600 nm.

Abstract: An adhesive containing a) a compound containing at least one vinyl ether group which has a molecular weight of more than 400 and b) a photoinitiator which initiates a polymerization of component A after exposure to light with a wavelength of 100 to 600 nm is useful for the production of a film laminate.

Abstract: A method of forming a film laminate uses an adhesive containing at least three components A, B and C. The method includes providing a radiation curable adhesive that contains a) a compound bearing at least one epoxy group, b) a compound with at least three OH groups and a molecular weight below 400 and c) a photoinitiator which initiates a polymerization of components a) and b) after exposure to light with a wavelength of 100 to 600 nm.

Abstract: Solvent-free and water-free radiation-curable primers based on hydroxy-functional prepolymers and cycloaliphatic epoxides or based on hydroxy-functional prepolymers and olefinically unsaturated compounds or based on epoxides and vinyl ethers together with cationic or free-radical initiators may be applied in the same manner as conventional commercial solvent-free laminating adhesives and, for many coatings, allow subsequent in-line coating without there being any need to evaporate solvent or water from the primer coating.