Abstract: Systems, devices, methods, and computer readable media for providing regulatory insight analysis are disclosed. In one implementation, the disclosed system may receive input data from a plurality of sources. Consistent with disclosed embodiments, the system may normalize the received input data. Further, the system may analyze the normalized input data, the analyzing comprising using logic for generating an output based on a first input including the normalized input data, a second input including calculation attributes, and a third input including one or more rules. The system may further be configured to store the output, continuously monitor the output as the output is stored, and generate one or more reports based on the stored output. Further, the system may receive, from a user and via a user interface, additional input data, a request to view the one or more generated reports, or a request for an additional output.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A method for displaying an advertisement includes storing, in a database, a plurality of keywords wherein each keyword in the plurality of keywords corresponds to a product or service, assigning a priority value to each keyword in the plurality of keywords, analyzing a webpage to identify a plurality of words displayed by the webpage. selecting a word in the plurality of words based on the assigned weight value, comparing the selected word to the plurality of keywords to obtain at least one matched keyword, selecting at least one keyword from the at least one matched keyword based on the assigned priority value, and modifying the webpage such that when a user of the webpage interacts with the selected word displayed by the webpage, an advertisement for the product or service corresponding to the at least one keyword is displayed.

Abstract: A method and apparatus are provided for coupling a pump to existing piping in a pump station such as a sewage or other suitable pump station. The adapter features a stand inlet adapter plate for coupling to one coupling of the existing piping; a pump adapter plate for coupling to a first port of the pump; and a clamp ring for coupling to the stand inlet adapter plate so as to allow the pump to be freely rotated a full 360° degrees if necessary in order to align another coupling of the existing piping to a second port of the pump, the stand inlet adapter plate being tightened and locked to the clamp ring after the pump is aligned for fastening the one coupling of the existing piping to the first port of the pump.

Abstract: A method and apparatus are provided for coupling a pump to existing piping in a pump station such as a sewage or other suitable pump station. The adapter features a stand inlet adapter plate for coupling to one coupling of the existing piping; a pump adapter plate for coupling to a first port of the pump; and a clamp ring for coupling to the stand inlet adapter plate so as to allow the pump to be freely rotated a full 360° degrees if necessary in order to align another coupling of the existing piping to a second port of the pump, the stand inlet adapter plate being tightened and locked to the clamp ring after the pump is aligned for fastening the one coupling of the existing piping to the first port of the pump.

Abstract: A computerized system for creating a new brokerage account is disclosed. A new account wizard software component guides a user through a series of data collection procedures using a rules based engine to facilitate data collection processing according to a plurality of data collection rules that are stored in a database. A workflow management software component manages data transfers and delegates task assignments during creation of the new brokerage account. There is also an application programming interface layer software component for interfacing data transfers between the workflow management software component and external software components.