Abstract: The present disclosure relates to combinations of a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease via administering to subjects in need thereof a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ?-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.

Abstract: The present disclosure relates to combinations of a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease via administering to subjects in need thereof a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein are systems and methods for ropeless fishing. The ropeless fishing system includes a surface subsystem installed on a vessel and at least one submerged subsystem submerged in a body of water. The surface subsystem includes acoustic transceiver and acoustic transducer units, which are configured to generate and omnidirectionally transmit an acoustic interrogation signal into the body of water surrounding the vessel and to directionally receive acoustic reply signals. The submerged subsystems include a compressed gas source and an enclosed flotation bag in fluid communication and an underwater acoustic actuator-transponder unit configured to receive the acoustic interrogation signal transmitted by the surface subsystem and to transmit an acoustic reply signal into the body of water. In addition, the submerged subsystem is further configured to control the flow of gas between the compressed gas source and the enclosed floatation bag to facilitate recovery of the submerged subsystem.

Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ?-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.

Abstract: An architecture for an inertial confinement fusion system is disclosed. The system includes a fusion chamber for producing neutrons from a fusion reaction, and a laser system in which lasers are arranged about a vacuum chamber to provide energy to the fusion chamber to initiate the fusion reaction. The beam paths between the lasers and the fusion chamber are configured to prevent neutrons from the fusion chamber from reaching the laser system at a level that would preclude human access to the laser system.

Abstract: The present disclosure relates to combinations of valproic acid or a pharmaceutically acceptable salt thereof, a ?-lactam compound or a pharmaceutically acceptable salt thereof, and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the combinations.

Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ?-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.

Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ?-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.

Abstract: The present disclosure relates to combinations of a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease via administering to subjects in need thereof a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof.

Abstract: An architecture for a fusion power plant is disclosed. The plant includes a fusion chamber for producing neutrons from a fusion reaction, and a laser system in which lasers are arranged about a vacuum chamber to provide energy to the fusion chamber to initiate the fusion reaction. The beam paths between the lasers and the fusion chamber are configured to prevent neutrons from the fusion chamber from reaching the laser system at a level that would preclude human access to the laser system.

Abstract: The invention is a flexible mat that can be placed on a floor or other large flat surface for the purpose of serving as a fully functional, oversized membrane computer keyboard with enlarged characters and keypad area. Each character depicted on the keyboard indicates a particular letter, numeral, function or symbol for input. Thereby, its user can enter information into a computer or electronic device through the keyboard by using alternative methods of input to traditional finger keystrokes. Rather, the user may utilize feet, knees, hands or other body parts and non-body parts instead of only fingers.

Abstract: Software comprised of three components which work together to authenticate a user when he attempts to remotely access the website of a financial institution using his personal computer. The software gathers and saves a set of informational statistics (SOIS) relative to the user's personal computer. Later, when the user attempts to access the financial institution's website, the software sends a series of informational inquires to the user's personal computer. These informational inquires seek statistical informational relative to the user's personal computer preferably comprised of a random subset of the SOIS. The software gathers the information needed to respond to the series of inquiries and the responses are compared with the SOIS information previously stored. Based upon this comparison, the software sends a message to the financial institution advising of the relative certainty that the user is authentic.

Abstract: The present invention relates to a method of treating infections in humans by administering a single dose of azithromycin.

Abstract: An anonymous trading system (FIG. 1) identifies the best bids and offers (QuoteSubmit, FIG. 3) from those counterparties (WS A1a1) with which each party (WS A1b1, WS A1b2, . . . . WSA2a2) is currently eligible to deal, while maintaining the anonymity of the potential counterparty and the confidentiality of any specific credit limitations imposed by the anonymous potential counterparty. To that end, each bid or offer (QuoteSubmit, FIG. 3) for a particular type of financial instrument is prescreened by the system for compatibility with limited credit information (for example, a one bit flag indicating whether a predetermined limit has already been exceeded) and an anonymous “Dealable” price (24,26) is calculated for each of the traders (WS A1b, . . . WS A2a) dealing with that particular financial instrument.

Abstract: The invention relates to an improved ejection seat restraint system for protecting the head and neck and spinal cord from injuries resulting from rapid forward deceleration and ejection from aircraft. The neck of human beings is at risk from lethal spinal cord injury with rupture of the atlanto-occipital membrane which holds the base of the skull to first cervical vertebra. Such lethal injuries according to the invention are prevented by a single inertial reel connection to the helmet of the user, at a point, aligned with or slightly above the superior nuchal line of the skull of the user. The helmet includes forehead padding, a wrap around cup shaped chin strap and an adjustable nape strap. The webbing for the inertial reel connection is preferably medium to soft.