Patents by Inventor Michael E. Bigler

Michael E. Bigler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FDF03 ANTIBODIES AND USES THEREOF
    Publication number: 20160068597
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 10, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • FDF03 ANTIBODIES AND USES THEREOF
    Publication number: 20150104453
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 16, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • FDF03 ANTIBODIES AND USES THEREOF
    Publication number: 20130156771
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Application
    Filed: February 14, 2013
    Publication date: June 20, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • FDF03 ANTIBODIES AND USES THEREOF
    Publication number: 20120258110
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 11, 2012
    Applicant: Schering Corporation
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • Methods of modulating CD200 receptors
    Patent number: 8263070
    Abstract: Provided are methods for modulating activity of the immune system using agonists or antagonists of a CD200 receptor. Also provided are methods of treatment and diagnosis of immune disorders.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: September 11, 2012
    Assignee: Schering Corporation
    Inventors: Holly M. Cherwinski, Michael E. Bigler, Jonathon D. Sedgwick, Joseph H. Phillips
  • MDL-1 USES
    Publication number: 20120177647
    Abstract: The invention provides methods for treating bone resorption disorders with antagonists of MDL-1.
    Type: Application
    Filed: March 23, 2012
    Publication date: July 12, 2012
    Applicant: Schering Corporation
    Inventors: Michael E. Bigler, Daniel J. Cua, Barbara Joyce-Shaikh, Joseph H. Phillips
  • Methods for inhibiting tumor growth or reducing metastatic burden in a subject by administering FDF03 antibodies
    Patent number: 8178094
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: May 15, 2012
    Assignee: Schering Corporation
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • Anti-MDL-1 antibodies
    Patent number: 8153134
    Abstract: Antibodies to human MDL-1 are provided, as well as uses thereof, e.g., in treatment of immune disorders, in particular, infectious diseases and sepsis.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: April 10, 2012
    Assignee: Schering Corporation
    Inventors: Michael E. Bigler, Paul G. Heyworth, Joseph H. Phillips, Leonard G. Presta
  • FDF03 Antibodies and uses thereof
    Publication number: 20110256143
    Abstract: The present invention relates to methods for identifying and using modulators of FDF03 biological activity in vitro and in vivo that are useful in the treatment of cancer.
    Type: Application
    Filed: December 18, 2008
    Publication date: October 20, 2011
    Applicant: Schering Corporation
    Inventors: Michael E. Bigler, Drake M. LaFace, Kalyan Pande, Joseph H. Phillips
  • MDL-1 USES
    Publication number: 20100221252
    Abstract: The invention provides methods for treating bone resorption disorders with antagonists of MDL-1.
    Type: Application
    Filed: June 24, 2008
    Publication date: September 2, 2010
    Inventors: Michael E Bigler, Daniel J. Cua, Barbara Joyce-Shaikh, Joseph H. Phillips
  • ANTI-MDL-1 ANTIBODIES
    Publication number: 20100150945
    Abstract: Antibodies to human MDL-1 are provided, as well as uses thereof, e.g., in treatment of immune disorders, in particular, infectious diseases and sepsis.
    Type: Application
    Filed: April 21, 2008
    Publication date: June 17, 2010
    Inventors: Michael E. Bigler, Paul G. Heyworth, Joseph H. Phillips, Leonard G. Presta
  • Methods of Modulating CD200 Receptors
    Publication number: 20080166353
    Abstract: Provided are methods for modulating activity of the immune system using agonists or antagonists of a CD200 receptor, Also provided are methods of treatment and diagnosis of immune disorders.
    Type: Application
    Filed: March 10, 2008
    Publication date: July 10, 2008
    Inventors: Holly M. Cherwinski, Michael E. Bigler, Jonathon D. Sedgwick, Joseph H. Phillips
  • Methods of modulating CD200 receptors
    Publication number: 20030223991
    Abstract: Provided are methods for modulating activity of the immune system using agonists or antagonists of a CD200 receptor. Also provided are methods of treatment and diagnosis of immune disorders.
    Type: Application
    Filed: March 13, 2003
    Publication date: December 4, 2003
    Inventors: Holly M. Cherwinski, Michael E. Bigler, Jonathon D. Sedgwick, Joseph H. Phillips