Abstract: Systems and methods to partially-gate PET data include acquisition of first data describing a plurality of coincidences detected during a scan of an object, each of the plurality of coincidences associated with a coincidence time and a line of response, determination of lines of response which pass through a region of the object, determination of time periods of motion of the region, modification of the first data to remove coincidences which are associated with the determined lines of response and which are associated with coincidence time during the determined time periods of motion of the region, reconstruction of an image of the object based on the modified first data, and display of the image.

Abstract: A system and method include acquisition of emission data from an object while a radioactive tracer is present in the object, determination of first parameters of a first Gaussian distribution representing a positron range distribution of the radioactive tracer, determination of second parameters of a second Gaussian distribution associated with imaging characteristics of the imaging system, generation of a system matrix based on the first parameters and the second parameters, reconstruction of a three-dimensional image based on the emission data and the system matrix, and display of the three-dimensional image.

Abstract: Systems and methods to partially-gate PET data include acquisition of first data describing a plurality of coincidences detected during a scan of an object, each of the plurality of coincidences associated with a coincidence time and a line of response, acquisition of a motion signal associated with motion of the object during the scan, determination of lines of response which are associated with a region of the object, determination of time periods of region motion based on the motion signal, modification of the first data to remove coincidences which are associated with the determined lines of response and which are associated with a coincidence time during a time period of region motion, reconstruction of an image of the object based on the modified first data, and display of the image.

Abstract: An image reconstruction system generates a motion estimation using images that have been reconstructed using AI processing. The system receives listmode data collected by an imaging system and produces two or more histo-images based on the listmode data. The system provides the two or more histo-images to an AI system and receives two or more AI reconstructed images back from the AI system based on the two or more histo-images. The system generates a motion estimation based on the two or more AI reconstructed images.

Abstract: An image reconstruction system generates a motion estimation using images that have been reconstructed using AI processing. The system receives listmode data collected by an imaging system and produces two or more histo-images based on the listmode data. The system provides the two or more histo-images to an AI system and receives two or more AI reconstructed images back from the AI system based on the two or more histo-images. The system generates a motion estimation based on the two or more AI reconstructed images.

Abstract: Systems and methods to partially-gate PET data include acquisition of first data describing a plurality of coincidences detected during a scan of an object, each of the plurality of coincidences associated with a coincidence time and a line of response, acquisition of a motion signal associated with motion of the object during the scan, determination of lines of response which are associated with a region of the object, determination of time periods of region motion based on the motion signal, modification of the first data to remove coincidences which are associated with the determined lines of response and which are associated with a coincidence time during a time period of region motion, reconstruction of an image of the object based on the modified first data, and display of the image.

Abstract: A method of conducting a multi-pass dynamic positron emission tomography (PET) scans using continuous bed motion (CBM) mode is disclosed where the method involves acquiring PET sinogram data using CBM mode as the patient bed is moving in a first direction; acquiring PET sonogram data using CBM mode as the patient bed is moving in a second direction that is opposite from the first direction; and reconstructing 3-D PET image from the acquired PET sonogram data.

Abstract: A method of processing and reconstructing dynamic positron emission tomography (PET) sinogram data comprises: acquiring PET sinogram data using continuous bed motion having a varying velocity; recording a plurality of position-time coordinate pairs while acquiring the PET sinogram data; determining respective acquisition times of each of a plurality of slices of the image, based on the plurality of position-time coordinates; and reconstructing respective parametric images for each respective slice in the plurality of slices.

Abstract: A method of processing and reconstructing dynamic positron emission tomography (PET) sinogram data comprises: acquiring PET sinogram data using continuous bed motion having a varying velocity; recording a plurality of position-time coordinate pairs while acquiring the PET sinogram data; determining respective acquisition times of each of a plurality of slices of the image, based on the plurality of position-time coordinates; and reconstructing respective parametric images for each respective slice in the plurality of slices.

Abstract: A method of conducting a multi-pass dynamic positron emission tomography (PET) scans using continuous bed motion (CBM) mode is disclosed where the method involves acquiring PET sinogram data using CBM mode as the patient bed is moving in a first direction; acquiring PET sonogram data using CBM mode as the patient bed is moving in a second direction that is opposite from the first direction; and reconstructing 3-D PET image from the acquired PET sonogram data.

Abstract: A method includes overlaying a grid on a set of dynamic PET, SPECT, CT or MR data, so as to define a set of voxels defining a plurality of cluster seeds; extracting a respective time activity curve (TAC) for dynamic PET or SPECT data or time varying signals in the case of dynamic CT or MR data, for each voxel based on the data; selecting a subset of the cluster seeds defined by the grid as initial cluster centroids of a set of clusters; assigning each TAC to a respective cluster in the set of clusters; computing a respective average TAC of each cluster; generating a parametric image based on the respective average TACs for the clusters; repeating the overlaying, determining, selecting, assigning, computing, and generating; and averaging the generated parametric images.

Abstract: Normalization coefficients in are computed for positron emission tomography (PET) continuous bed motion acquisition (CBM). The normalization coefficients for the lines-of-response in CBM account for the change in decay of the injected isotope over time and/or changes in velocity of the bed motion.

Abstract: A method includes overlaying a grid on a set of dynamic PET, SPECT, CT or MR data, so as to define a set of voxels defining a plurality of cluster seeds; extracting a respective time activity curve (TAC) for dynamic PET or SPECT data or time varying signals in the case of dynamic CT or MR data, for each voxel based on the data; selecting a subset of the cluster seeds defined by the grid as initial cluster centroids of a set of clusters; assigning each TAC to a respective cluster in the set of clusters; computing a respective average TAC of each cluster; generating a parametric image based on the respective average TACs for the clusters; repeating the overlaying, determining, selecting, assigning, computing, and generating; and averaging the generated parametric images.

Abstract: Methods and systems for processing data for medical imaging are disclosed. The method includes obtaining a set of continuous bed motion (CBM) data from a first imaging modality. The set of CBM data includes a plurality of gating signals. A CBM normalization matrix is calculated. The CBM normalization matrix calculation includes the plurality of gating signals. An image is reconstructed from the CBM data and the CBM normalization matrix. The first imaging modality can be a PET imaging device.

Abstract: Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.

Abstract: Methods and systems for processing data for medical imaging are disclosed. The method includes obtaining a set of continuous bed motion (CBM) data from a first imaging modality. The set of CBM data includes a plurality of gating signals. A CBM normalization matrix is calculated. The CBM normalization matrix calculation includes the plurality of gating signals. An image is reconstructed from the CBM data and the CBM normalization matrix. The first imaging modality can be a PET imaging device.

Abstract: Methods, and systems therefrom, for generating images from time of flight (TOF) data associated with a scan of at least one object using a positron emission tomography system are provided. The method includes providing initial values for an activity image to yield a current activity image. The method also includes estimating initial values for an attenuation map (?-map) image based on the TOF data to yield a current ?-map image. The method further includes repeating, until at least one termination condition is met, the steps of updating the current activity image based on at least the current ?-map and a first update algorithm and updating the current ?-map image based on at least on the updated activity image and a second update algorithm. The method also includes outputting an image of the at least one object based on the current ?-map and the current activity image.

Abstract: Normalization coefficients in are computed for positron emission tomography (PET) continuous bed motion acquisition (CBM). The normalization coefficients for the lines-of-response in CBM account for the change in decay of the injected isotope over time and/or changes in velocity of the bed motion.

Abstract: Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.

Abstract: A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.