Patents by Inventor Michael E. Dolan

Michael E. Dolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF PRODUCING AN ANTI-a4B7 ANTIBODY
    Publication number: 20220267449
    Abstract: Provided herein are methods for purifying an anti-?4?7 integrin antibody, such as vedolizumab, from a liquid solution, e.g., from a mammalian cell culture clarified harvest. The invention relates, inter alia, to purification methods for controlling the amount of product-related substances and/or process-related impurities present in purified preparations of an anti-?4?7 integrin antibody, or antigen-binding fragment thereof, e.g., vedolizumab. Compositions comprising an anti-?4?7 antibody, and uses thereof to treat a disorder, are also provided.
    Type: Application
    Filed: June 10, 2020
    Publication date: August 25, 2022
    Inventors: Debra Ameli, Susan R. Carter, Michael E. Dolan, Nicole Hilo, Amitava Kundu, Amy Miller, George Parks, Olga Paley, Paras Bhatia
  • ANTIBODY PURIFICATION METHODS AND COMPOSITIONS THEREOF
    Publication number: 20220259291
    Abstract: Methods of purifying a humanized ?4?7 antibody, such as vedolizumab, produced in a mammalian cell culture are described herein, as are compositions resulting from said purification processes.
    Type: Application
    Filed: June 10, 2020
    Publication date: August 18, 2022
    Inventors: Sheldon F. OPPENHEIM, George Parks, Norbert Schuelke, Lulfiye Kurt, Michael E. Dolan