Patents by Inventor Michael E. Flaugh

Michael E. Flaugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Melatonin derivatives for use in treating desynchronization disorders
    Patent number: 6180657
    Abstract: The present invention provides a method of treating desynchronization disorders using various melatonin analogs.
    Type: Grant
    Filed: November 18, 1993
    Date of Patent: January 30, 2001
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • Substituted 1,2,3,4-tetrahydro-2-dibenzofuranamines and 2-aminocyclohepta?6,!benzofurans
    Patent number: 5935992
    Abstract: The invention provides substituted-2-amino-1,2,3,4-tetrahydrodibenzofurans and 2-aminocyclohepta?b!benzo-furans useful as 5-HT.sub.1F agonists.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 10, 1999
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Anton D. Kiefer, Jr.
  • Substituted 1,2,3,4-tetrahydro-2-dibenzofuranamines and 2-aminocyclohepta?6,!benzofurans
    Patent number: 5932739
    Abstract: The invention provides substituted-2-amino-1,2,3,4-tetrahydrodibenzofurans and 2-aminocyclohepta?b!benzo-furans useful as 5-HT.sub.1F agonists.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 3, 1999
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Anton D. Kiefer, Jr.
  • Substituted 1, 2, 3, 4-tetrahydro-2-dibenzofuranamines and 2-amino-cyclohepta (6, 7-B) Benzofurans
    Patent number: 5846995
    Abstract: The invention provides substituted-2-amino-1,2,3,4-tetrahydrodibenzofurans and 2-aminocyclohepta?b!benzo-furans useful as 5-HT.sub.1F agonists.
    Type: Grant
    Filed: August 25, 1997
    Date of Patent: December 8, 1998
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Anton D. Kiefer, Jr.
  • 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz?CD!indoles
    Patent number: 5783590
    Abstract: 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz?cd!indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: July 21, 1998
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Michael E. Flaugh, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • Melatonin derivatives for use in treating sleep disorders
    Patent number: 5654325
    Abstract: The present invention provides a method of treating sleep disorders using various melatonin analogs.
    Type: Grant
    Filed: November 18, 1993
    Date of Patent: August 5, 1997
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
    Patent number: 5594019
    Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: August 31, 1994
    Date of Patent: January 14, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Michael E. Flaugh, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • 6-substituted-hexahydrobenz [CD] indoles
    Patent number: 5470853
    Abstract: The present invention provides 4-amino-6-substituted-hexahydrobenz[cd]indoles which are useful in treating disease states which can be benefited by an alteration of 5-HT.sub.1.sbsb.A receptors.
    Type: Grant
    Filed: March 30, 1994
    Date of Patent: November 28, 1995
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Michael J. Martinelli
  • Tetrahydrobenz[c,d]indole serotonin agonists
    Patent number: 5462962
    Abstract: This invention provides 6-substituted-4-(amino or substituted amino)tetrahydrobenz[c,d]indole serotonin agonists useful in treating a variety of conditions associated with serotonin function.
    Type: Grant
    Filed: December 15, 1992
    Date of Patent: October 31, 1995
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Mark M. Foreman
  • Tetrahydrobenz [CD] indazoles, compositions and use
    Patent number: 5385928
    Abstract: A series of 1,3,4,5-tetrahydrobenz[c,d]indazoles having activities as regulators of serotonin functions, particularly in the brain.
    Type: Grant
    Filed: May 18, 1994
    Date of Patent: January 31, 1995
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
    Patent number: 5347013
    Abstract: 6-Heterocyclic-4-amino-l,2,2a,3,4,5-hexahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: September 30, 1992
    Date of Patent: September 13, 1994
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Michael E. Flaugh, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • 6-substituted-hexahydrobenz[cd]indoles
    Patent number: 5302612
    Abstract: The present invention provides 4-amino-6-substituted-hexahydrobenz[cd]indoles which are useful in treating disease states which can be benefited by an alteration of 5-HT.sub.1A receptors.
    Type: Grant
    Filed: May 27, 1993
    Date of Patent: April 12, 1994
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Michael J. Martinelli
  • 6-substituted-tetrahydrobenz[cd]indoles
    Patent number: 5229409
    Abstract: The present invention involves certain 4-amino-6-substituted-tetrahydrobenz[cd]indoles and their use in treating disorders which can be benefited by modifying 5-HT A receptor function.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: July 20, 1993
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Michael J. Martinelli, John M. Schaus
  • 6-substituted-hexahydrobenz[cd]indoles
    Patent number: 5229410
    Abstract: The present invention provides 4-amino-6-substituted-hexahydrobenz[cd]indoles which are useful in treating disease states which can be benefited by an alteration of 5-HT.sub.1A receptors.
    Type: Grant
    Filed: July 3, 1991
    Date of Patent: July 20, 1993
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Michael J. Martinelli, John M. Schaus
  • Tetrahydrobenz(c,d)indole serotonin agonists
    Patent number: 5204340
    Abstract: This invention provides 6-substituted-4-(amino or substituted amino)tetrahydrobenz[c,d]indole serotonin agonists useful in treating a variety of conditions associated with serotonin function.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: April 20, 1993
    Assignee: Eli Lilly and Company
    Inventors: Michael E. Flaugh, Mark M. Foreman
  • Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
    Patent number: 5196435
    Abstract: Derivatives of melatonin and the pharmaceutically acceptable salts thereof are useful for therapeutically treating hormonally dependent mammalian breast carcinoma. Combination treatments of melatonin derivatives and an antiestrogen compound are especially useful.
    Type: Grant
    Filed: November 21, 1991
    Date of Patent: March 23, 1993
    Assignee: Eli Lilly and Company
    Inventors: James A. Clemens, Michael E. Flaugh
  • 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
    Patent number: 5026869
    Abstract: (.+-.)-4-substitutedamino-6-alkoxy, benzyloxy, acyloxy, or hydroxy-1,3,4,5-tetrahydrobenz[c,d]indoles, pharmaceutically acceptable salts thereof are, anti-depressants.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: June 25, 1991
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • .beta.-alkylmelatonins as ovulation inhibitors
    Patent number: 4997845
    Abstract: .beta.-Alkylmelatonins are useful as ovulation inhibitors.
    Type: Grant
    Filed: May 10, 1990
    Date of Patent: March 5, 1991
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
    Patent number: 4983622
    Abstract: (.+-.)-4-substitutedamino-6-alkoxy, benzyloxy, acyloxy, or hydroxy-1,3,4,5-tetrahydrobenz[c,d]indoles, pharmaceutically acceptable salts thereof, are anti-depressants.
    Type: Grant
    Filed: February 1, 1985
    Date of Patent: January 8, 1991
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh
  • 6,7-dihalomelatonins
    Patent number: 4614807
    Abstract: 6,7-Dichloromelatonin and related compounds are ovulation inhibitors of the formula ##STR1## wherein R and R.sup.1 are individually F or Cl, R.sup.2 is C.sub.1-3 alkyl, including methyl, ethyl, n-propyl and isopropyl, and R.sup.3 is H or methyl.
    Type: Grant
    Filed: October 4, 1984
    Date of Patent: September 30, 1986
    Assignee: Eli Lilly and Company
    Inventor: Michael E. Flaugh