Patents by Inventor Michael E. KINZIE
Michael E. KINZIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 11773363Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: GrantFiled: December 2, 2022Date of Patent: October 3, 2023Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 11746319Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: GrantFiled: June 1, 2020Date of Patent: September 5, 2023Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Configurable Methods And Systems Of Growing And Harvesting Cells In A Hollow Fiber Bioreactor System
Publication number: 20230102100Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: ApplicationFiled: December 2, 2022Publication date: March 30, 2023Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 11613727Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: GrantFiled: September 30, 2020Date of Patent: March 28, 2023Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Configurable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20210024876Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: ApplicationFiled: September 30, 2020Publication date: January 28, 2021Applicant: Terumo BCT, Inc.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 10870827Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: GrantFiled: August 7, 2017Date of Patent: December 22, 2020Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Customizable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20200291346Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: ApplicationFiled: June 1, 2020Publication date: September 17, 2020Applicant: Terumo BCT, Inc.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 10669519Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: GrantFiled: May 31, 2017Date of Patent: June 2, 2020Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Configurable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20170335270Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: ApplicationFiled: August 7, 2017Publication date: November 23, 2017Applicant: Terumo BCT, Inc.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Customizable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20170267966Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: ApplicationFiled: May 31, 2017Publication date: September 21, 2017Applicant: Terumo BCT, Inc.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 9725689Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: GrantFiled: October 7, 2011Date of Patent: August 8, 2017Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Patent number: 9695393Abstract: One or more embodiments are described directed to a method and system for concentrating components of a fluid circulated through a cell growth chamber such as a cell growth chamber. Accordingly, embodiments include methods and systems that utilize a tangential flow filter to concentrate components of a fluid that in embodiments includes expanded cells. In embodiments, a concentrated fluid component and a concentrated cell component are generated by flowing the fluid with expanded cells across a tangential flow filter. The concentrated cell component may be recirculated to the tangential flow filter to reach some desired concentration of cells. The concentrated fluid component may be collected to utilize cellular-produced constituents in the concentrated fluid component.Type: GrantFiled: August 20, 2013Date of Patent: July 4, 2017Assignee: Terumo BCT, Inc.Inventors: Brian J. Nankervis, Thomas G. DiLorenzo, Michael E. Kinzie, Mark E. Jones
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Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
Patent number: 9677042Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: GrantFiled: October 7, 2011Date of Patent: June 13, 2017Assignee: Terumo BCT, Inc.Inventors: Edward Allan Stanton, IV, Glen Delbert Antwiler, Patrick J. Howley, Michael E. Kinzie, Jon A. Dodd, Casey V. Medina -
Patent number: 9670451Abstract: Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.Type: GrantFiled: November 20, 2014Date of Patent: June 6, 2017Assignee: Terumo BCT, Inc.Inventors: Thomas G. Dilorenzo, Edward Allan Stanton, IV, Glen Delbert Antwiler, Michael E. Kinzie, Brian J. Nankervis, Monique Givens, Casey V. Medina, Jon A. Dodd
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Publication number: 20150079664Abstract: Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.Type: ApplicationFiled: November 20, 2014Publication date: March 19, 2015Applicant: TERUMO BCT, INC.Inventors: Thomas G. DILORENZO, Edward Allan STANTON, IV, Glen Delbert ANTWILER, Michael E. KINZIE, Brian J. NANKERVIS, Monique GIVENS, Casey V. MEDINA, Jon A. DODD
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Patent number: 8895291Abstract: Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.Type: GrantFiled: October 7, 2011Date of Patent: November 25, 2014Assignee: Terumo BCT, Inc.Inventors: Thomas G. Dilorenzo, Edward Allan Stanton, IV, Glen Delbert Antwiler, Michael E. Kinzie, Brian J. Nankervis, Monique Givens, Casey V. Medina, Jon A. Dodd
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Publication number: 20140051167Abstract: One or more embodiments are described directed to a method and system for concentrating components of a fluid circulated through a cell growth chamber such as a cell growth chamber. Accordingly, embodiments include methods and systems that utilize a tangential flow filter to concentrate components of a fluid that in embodiments includes expanded cells. In embodiments, a concentrated fluid component and a concentrated cell component are generated by flowing the fluid with expanded cells across a tangential flow filter. The concentrated cell component may be recirculated to the tangential flow filter to reach some desired concentration of cells. The concentrated fluid component may be collected to utilize cellular-produced constituents in the concentrated fluid component.Type: ApplicationFiled: August 20, 2013Publication date: February 20, 2014Applicant: Terumo BCT, Inc.Inventors: Brian J. NANKERVIS, Thomas G. DiLorenzo, Michael E. Kinzie, Mark E. Jones
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Customizable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20120089930Abstract: Embodiments described herein generally relate to methods and systems for customizing protocols for use with a cell expansion system. Through a user interface, a user may create a custom task for loading, growing and/or harvesting cells. A custom task may comprise one or more steps, in which a user may add or omit steps, as desired. Data may be entered for settings associated with a custom task, in which embodiments provide for such data to be entered each time the custom task is performed. In another embodiment, the settings for a custom task may be configured, in which such settings may be stored and retrieved upon selection of the custom task. Customization and configuration of a custom task may occur using a diagram view of the cell expansion system, in which process settings are associated with graphical user interface elements.Type: ApplicationFiled: October 7, 2011Publication date: April 12, 2012Applicant: CARIDIANBCT, INC.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. Medina -
Configurable Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System
Publication number: 20120086657Abstract: Embodiments described herein generally relate to methods and systems for configuring settings of a cell expansion system including a bioreactor. Through a user interface, a user may configure display settings, system settings, and settings associated with protocols for loading, growing and/or harvesting cells. In configuring settings for protocols and associated processes, a diagram view or window of the cell expansion system is displayed in embodiments. The diagram view displays the process settings as graphical user interface elements. Settings available for configuration are enabled for selection in the diagram view. The diagram view allows the user to visualize the settings available for task configuration and to configure enabled settings. Configured settings are stored and capable of retrieval for subsequent execution or modification of the applicable protocol.Type: ApplicationFiled: October 7, 2011Publication date: April 12, 2012Applicant: CARIDIANBCT, INC.Inventors: Edward Allan STANTON, IV, Glen Delbert ANTWILER, Patrick J. HOWLEY, Michael E. KINZIE, Jon A. DODD, Casey V. MEDINA -
Publication number: 20120088224Abstract: Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber.Type: ApplicationFiled: October 7, 2011Publication date: April 12, 2012Applicant: CARIDIANBCT, INC.Inventors: Thomas G. DILORENZO, Edward Allan STANTON, IV, Glen Delbert ANTWILER, Michael E. KINZIE, Brian J. Nankervis, Monique Givens, Casey V. Medina, Jon A. Dodd