Patents by Inventor Michael E. Phelps

Michael E. Phelps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic chemical reaction circuits
    Patent number: 8206593
    Abstract: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: June 26, 2012
    Assignees: Fluidigm Corporation, California Institute of Technology, The Regents of the University of California, Siemens Medical Solutions USA, Inc.
    Inventors: Chung-cheng Lee, Guodong Sui, Arkadij Elizarov, Hartmuth C. Kolb, Jiang Huang, James R. Heath, Michael E. Phelps, Stephen R. Quake, Hsian-rong Tseng, Paul Wyatt, Antoine Daridon
  • Microfluidic Chemical Reaction Circuits
    Publication number: 20080281090
    Abstract: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.
    Type: Application
    Filed: December 5, 2005
    Publication date: November 13, 2008
    Applicants: CALIFORNIA INSTITUTE OF TECHNOLOGY, FLUIDIGM CORPORATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SIEMENS CORPORATION
    Inventors: Cheng-Chung Lee, Guodong Sui, Arkadij Elizarov, Hartmuth C. Kolb, Jiang Huang, James R. Heath, Michael E. Phelps, Stephen R. Quake, Hsian-rong Tseng, Paul Wyatt, Antoine Daridon
  • Cyclooxygenase-2 selective agents useful as imaging probes and related methods
    Patent number: 7329401
    Abstract: This invention provides novel cyclooxygenase-2 selective agents that are particularly useful as imaging probes in non-invasive imaging techniques, such as PET and SPECT. Preferred cyclooxygenase-2 selective agents inhibit cyclooxygenase-2 activity with greater potency and specificity than conventional cyclooxygenase-2 inhibitors. Other aspects of the invention include pharmaceutical compositions including the cyclooxygenase-2 selective agents as well as methods for detecting and/or inhibiting cyclooxygenase-2. These methods are particularly useful for diagnosing and treating disorders, such as inflammation, which is characterized by elevated cyclooxygenase-2 levels.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: February 12, 2008
    Assignee: The Regents of the University of California
    Inventors: Tatsushi Toyokuni, Nagichettiar Satyamurthy, Harvey R. Herschman, Michael E. Phelps, Jorge R. Barrio
  • 8-fluoropurine compounds
    Patent number: 6262254
    Abstract: An efficient, regiocontrolled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F2 in He or other inert gas.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: July 17, 2001
    Assignee: The Regents of Univ. of California
    Inventors: Jorge R. Barrio, Nagichettiar Satyamurthy, Mohammad Namavari, Michael E. Phelps
  • Process for producing 8-fluoropurines
    Patent number: 5861503
    Abstract: An efficient, regiocontrolled approach to the synthesis of 8-fluoropurines by direct fluorination of purines with dilute elemental fluorine, or acetyl hypofluorite, is provided. In a preferred embodiment, a purine compound is dissolved in a polar solvent and reacted with a dilute mixture of F.sub.2 in He or other inert gas.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: January 19, 1999
    Assignee: The Regents of the University of California
    Inventors: Jorge R. Barrio, Nagichettiar Satyamurthy, Mohammad Namavari, Michael E. Phelps