Abstract: A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.

Abstract: A spectrometer in accordance with the present disclosure may provide multiple optical paths from the inputs to the camera, where the paths are as nearly identical as possible. For example, a spectrometer in accordance with the present disclosure may include multiple inputs, input optics, a diffraction grating, output optics, and a camera. The multiple inputs may be imaged onto different sections of the camera using the same input optics, the same diffraction grating, and the same output optics.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: An optical coherence tomography (OCT) imaging system is disclosed. In an embodiment of the invention, an OCT imaging system may include (a) multiple scan geometries, including a lateral scan of a beam perpendicular to the scan direction and a rotating scan where the beam is perpendicular to a curved surface (such as the front of the eye), and (b) a low coherence interferometry engine based on spectral domain interferometry, with a spectrometer capable of ultra deep imaging.

Abstract: A spectrometer in accordance with the present disclosure may provide multiple optical paths from the inputs to the camera, where the paths are as nearly identical as possible. For example, a spectrometer in accordance with the present disclosure may include multiple inputs, input optics, a diffraction grating, output optics, and a camera. The multiple inputs may be imaged onto different sections of the camera using the same input optics, the same diffraction grating, and the same output optics.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: The invention provides unitary optics modules that integrate several light management functions for performing optical spectroscopy, such as Raman spectroscopy, and optical spectroscopy systems that include one or more of the unitary optics modules. Methods of using the modules and systems are also provided.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: A system and method are provided for imaging a test substrate having a test surface that is configured to enable spectroscopic detection of one or more chemical or biological species, wherein the test surface includes a testing site disposed thereon according to a predetermined spatial pattern. The test substrate is provided in an image plane or a Fourier Transform plane of a sensor. The invention provides high throughput and high spectral resolution.

Abstract: Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein.

Abstract: The invention provides unitary optics modules that integrate several light management functions for performing optical spectroscopy, such as Raman spectroscopy, and optical spectroscopy systems that include one or more of the unitary optics modules. Methods of using the modules and systems are also provided.

Abstract: A system for imaging a sample is provided that includes an optical coherence tomography (OCT) portion having an associated OCT path. A second imaging portion is provided having an associated second image path, different from the OCT path. A fixation target having an associated fixation path, different from the second image path and the OCT path is also provided. The OCT path, the second image path and the fixation path are confocal at a common image plane. Related handheld systems are also provided.

Abstract: A class of aperture coded spectrometer is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spatial resolution by replacing the slit of conventional dispersive spectrometers with a spatial filter or mask. A number of masks can be used including Harmonic masks, Legendre masks, and Hadamard masks.

Abstract: A spatial filter for an optical system, such as an optical spectrometer, collects and spatially filters light using a fiber bundle having a plurality of fibers disposed therein. At an input end of the fiber bundle, the fibers are typically packed tightly together to optimize the collection efficiency. At an output end, the fibers are spread out from the fiber bundle and arranged within a two-dimensional output area according to a two-dimensional pattern corresponding to a coded aperture function. As a result, the two-dimensional pattern of the output end spatially filters the light collected by the input end. Corresponding methods are also described.

Abstract: A class of aperture coded spectrometer is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spatial resolution by replacing the slit of conventional dispersive spectrometers with a spatial filter or mask. A number of masks can be used including Harmonic masks, Legendre masks, and Hadamard masks.

Abstract: A spatial filter for an optical system, such as an optical spectrometer, collects and spatially filters light using a fiber bundle having a plurality of fibers disposed therein. At an input end of the fiber bundle, the fibers are typically packed tightly together to optimize the collection efficiency. At an output end, the fibers are spread out from the fiber bundle and arranged within a two-dimensional output area according to a two-dimensional pattern corresponding to a coded aperture function. As a result, the two-dimensional pattern of the output end spatially filters the light collected by the input end. Corresponding methods are also described.

Abstract: A prescription verification system includes a database that contains a plurality of spectral signatures corresponding to identified pharmaceuticals. A multimodal multiplex sampling (MMS) spectrometer obtains a spectra of a pharmaceutical to be identified and verified. The pharmaceutical can be inside or out of a vial. The prescription verification system includes algorithms for matching spectra of pharmaceuticals to be verified obtaining using the MMS spectrometer to spectral signatures contained in the database corresponding to identified pharmaceuticals. The prescription verification system further includes algorithms for identifying such pharmaceuticals to be verified.