Patents by Inventor Michael E. Trama

Michael E. Trama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7182937
    Abstract: A composition for reducing dentinal hypersensitivity and remineralizing exposed dentinal surface and open dentinal tubules, comprising a non-aqueous carrier and a desensitizing amount of a desensitizing/remineralizing agent which consists essentially of a water soluble calcium salt and an incompatible ingredient which would otherwise react with the calcium salt. Upon contact with saliva when applied to an oral cavity, the desensitizing/remineralizing is then formed in situ by the reaction between the calcium salt and the incompatible ingredient, thereby remineralizing exposed dentinal surface and open dentinal tubules.
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: February 27, 2007
    Assignee: Block Drug Company, Inc.
    Inventors: Jin Xu, Stephen W. Mruphy, Bala Nayar, Michael E. Trama
  • Publication number: 20040047814
    Abstract: A composition for reducing dentinal hypersensitivity and remineralizing exposed dentinal surface and open dentinal tubules, comprising a non-aqueous carrier and a desensitizing amount of a desensitizing/remineralizing agent which consists essentially of a water soluble calcium salt and an incompatible ingredient which would otherwise react with the calcium salt. Upon contact with saliva when applied to an oral cavity, the desensitizing/remineralizing is then formed in situ by the reaction between the calcium salt and the incompatible ingredient, thereby remineralizing exposed dentinal surface and open dentinal tubules.
    Type: Application
    Filed: July 29, 2003
    Publication date: March 11, 2004
    Inventors: Jin Xu, Stephen W. Mruphy, Bala Nayar, Michael E. Trama
  • Publication number: 20030215401
    Abstract: A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent, preferably a combination of two such agents; and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt, at least one strontium salt, and mixtures thereof, wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules, retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules. The compositions may further contain a source of physiologically acceptable fluoride ion, such as stannous fluoride. Also disclosed are methods of using the subject compositions in the treatment of sensitive teeth.
    Type: Application
    Filed: February 6, 2003
    Publication date: November 20, 2003
    Inventors: David Estrada, Benjamin D Fitz, Jan F Macik, Neil J Napolitano, Alfred J Smetana, Joseph D Synoids, Michael E Trama
  • Publication number: 20020041852
    Abstract: A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent, preferably a combination of two such agents; and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt, at least one strontium salt, and mixtures thereof, wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules, retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules. The compositions may further contain a source of physiologically acceptable fluoride ion, such as stannous fluoride. Also disclosed are methods of using the subject compositions in the treatment of sensitive teeth.
    Type: Application
    Filed: May 7, 2001
    Publication date: April 11, 2002
    Inventors: Neil J. Napolitano, Alfred J. Smetana, Joseph D. Synodis, Jan F. Macik, Michael E. Trama, David Estrada, Benjamin D. Fitz
  • Patent number: 6121213
    Abstract: A denture cream for cleaning dentures and removable dental prostheses comprising a peroxide stabilized against chemical degradation by a combination of a bicarbonate and a phosphate, such as an alkali monofluorophosphate.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: September 19, 2000
    Assignee: Block Drug Company, Inc.
    Inventors: Democrita E. Vergara, Michael E. Trama, Kuo-Chen Yeh