Patents by Inventor Michael E. Ultee

Michael E. Ultee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecule labelling using 2-hydraninopyridine derivatives
    Patent number: 5679778
    Abstract: A compound of formula I ##STR1## in which E is an alkenyl group or represents H.sub.2 in which case the compound is in acid addition salt form, J is selected from --CO--NH--, --CO--O--, --CO--S-- and --NH--CO--, T is an alkylene chain, or, if J is --CO--NH--, T is the residue of an amino acid moiety, Q is a hydrophilic or cleavable moiety, and Z is an amine- and/or thiol-reactive moiety. Conjugates formed by reacting such compound with a macromolecule, e.g. an immunoglobulin, and labelled macromolecules comprising a metal atom bound to such conjugate are also disclosed.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: October 21, 1997
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Michael J. Abrams, Gary J. Bridger, David A. Schwartz, Sreenivasan Padmanabhan, Michael E. Ultee