Abstract: A nucleic acid comprising a continuous nucleotide sequence, containing: (i) a gene encoding LuxA, (ii) a gene encoding LuxB, (iii) a gene encoding LuxC, (iv) a gene encoding LuxD, (v) a gene encoding LuxE, wherein each of the genes is under the control of a promoter heterologous to the respective gene, and wherein all of the genes together with the promoter are contained in a single nucleotide sequence in a row. The vectors and host cells comprise the nucleic acid. Methods of producing a host cell and methods and uses for detecting an environmental effect and a kit therefor.

Abstract: An aluminium alloy foil with a thickness of maximum 12 ?m, maximum 9 ?m or less than 8 ?m. The aluminium alloy foil is an AA1xxx or A8xxx aluminium alloy in the annealed state. In addition, a method for manufacturing an aluminium alloy foil and its use. The object of proposing an aluminium alloy foil with improved barrier properties, a method for its manufacture and a use of the aluminium alloy foil is achieved in that the aluminium alloy foil has a maximum number of pores with a pore size of 1 ?m to 200 ?m of maximum 12 per dm2, maximum 8 per dm2 or maximum 6 per dm2. In addition, a method is specified for how this aluminium alloy foil can be manufactured.

Abstract: The present invention pertains inter alia to a method for analyzing a sample comprising biomolecules, which comprises the following steps: A a) lysing the sample to provide a lysed sample and optionally clearing the lysed sample; b) contacting at least a portion of the lysed sample with a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition; or B a) contacting the sample with a lysis solution thereby providing a lysis mixture; b) using the lysis mixture to reconstitute a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition, wherein the reconstituted composition is optionally cleared and wherein subsequent to step b) at least one step is performed which supports the lysis of the sample.

Abstract: A high voltage connector for establishing a high voltage connection between two high voltage lines is disclosed, with the high voltage connector including a carrier element with a first guiding groove and a second guiding groove, wherein the carrier element includes a high voltage insulating material, wherein the first guiding groove and the second guiding groove are arranged parallel to one another and extend in the longitudinal direction of the carrier element, and wherein each of the first guiding groove and the second guiding groove is designed for accommodating a wire of each of a first high voltage line and a second high voltage line. In this way, a high voltage connection can be established which is insensitive to electrical interference, as well as mechanically stable and resistive, and also works at critical pressure.

Abstract: A sample cooling device for histological samples is connectable to a power network for supplying electrical voltage to the device. The sample cooling device comprises a measuring apparatus for measuring a magnitude of an input line voltage present at the sample cooling device, and a transformer having a primary coil that comprises at least three coil pickoffs, and a secondary coil. The sample cooling device further comprises a switching means that connects two of the coil pickoffs to the power network as a function of the magnitude of the input line voltage, so that a magnitude of an output voltage present at the secondary coil has a predefined or predefinable voltage value irrespective of the magnitude of the input voltage. A corresponding method for supplying electrical power to a sample cooling device for histological samples is also disclosed.

Abstract: A high voltage connector for establishing a high voltage connection between two high voltage lines is disclosed, with the high voltage connector including a carrier element with a first guiding groove and a second guiding groove, wherein the carrier element includes a high voltage insulating material, wherein the first guiding groove and the second guiding groove are arranged parallel to one another and extend in the longitudinal direction of the carrier element, and wherein each of the first guiding groove and the second guiding groove is designed for accommodating a wire of each of a first high voltage line and a second high voltage line. In this way, a high voltage connection can be established which is insensitive to electrical interference, as well as mechanically stable and resistive, and also works at critical pressure.

Abstract: The invention relates, in accordance with one aspect, to a portable device for transporting at least one histological sample or at least one cassette containing a histological sample. The device is attachable to a processing station for processing 5 histological samples. In the attached state, energy for cooling the histological sample is transferred from the processing station to the device or vice versa. In accordance with another aspect of the invention, a processing station for processing a histological sample is provided, which station is embodied for releasable attachment of a portable device. The processing station is further embodied to transfer energy 10 for cooling to, or receive it from, an attached device.

Abstract: A freezing microtome for the production of microscopable thin sections of tissue samples (60), comprising a cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) for freezing the tissue samples (60), a cutting device for cutting the frozen tissue samples (60) and a working chamber, in which the cutting device and at least a part of the cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) are arranged is described. The part of the cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) arranged in the working chamber contains a liquid coolant (70), in which the tissue samples (60) can be inserted for freezing.

Abstract: A sample cooling device for histological samples is connectable to a power network for supplying electrical voltage to the device. The sample cooling device comprises a measuring apparatus for measuring a magnitude of an input line voltage present at the sample cooling device, and a transformer having a primary coil that comprises at least three coil pickoffs, and a secondary coil. The sample cooling device further comprises a switching means that connects two of the coil pickoffs to the power network as a function of the magnitude of the input line voltage, so that a magnitude of an output voltage present at the secondary coil has a predefined or predefinable voltage value irrespective of the magnitude of the input voltage. A corresponding method for supplying electrical power to a sample cooling device for histological samples is also disclosed.

Abstract: The present invention pertains inter alia to a method for analysing a sample comprising biomolecules, which comprises the following steps: A a) lysing the sample to provide a lysed sample and optionally clearing the lysed sample; b) contacting at least a portion of the lysed sample with a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition; or B a) contacting the sample with a lysis solution thereby providing a lysis mixture; b) using the lysis mixture to reconstitute a dry composition comprising reagents for performing the analytical method, thereby providing a reconstituted composition; c) performing an analytical method using the reconstituted composition, wherein the reconstituted composition is optionally cleared and wherein subsequent to step b) at least one step is performed which supports the lysis of the sample.

Abstract: The invention relates, in accordance with one aspect, to a portable device for transporting at least one histological sample or at least one cassette containing a histological sample. The device is attachable to a processing station for processing 5 histological samples. In the attached state, energy for cooling the histological sample is transferred from the processing station to the device or vice versa. In accordance with another aspect of the invention, a processing station for processing a histological sample is provided, which station is embodied for releasable attachment of a portable device. The processing station is further embodied to transfer energy 10 for cooling to, or receive it from, an attached device.

Abstract: A freezing microtome for the production of microscopable thin sections of tissue samples (60), comprising a cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) for freezing the tissue samples (60), a cutting device for cutting the frozen tissue samples (60) and a working chamber, in which the cutting device and at least a part of the cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) are arranged is described. The part of the cooling device (24, 34, 36, 38, 40, 42, 46, 48, 50, 52) arranged in the working chamber contains a liquid coolant (70), in which the tissue samples (60) can be inserted for freezing.

Abstract: A complexity vector representing a complexity of at least part of an SVG scene is generated based on a complexity variable associated with at least one element of a DOM tree of the SVG scene. The playback suitability of at least part of an SVG scene is tested for a device based on whether a complexity variable of a complexity vector of the SVG scene is smaller than or equal to the associated device complexity variable of a device complexity vector of the device per element, wherein a maximum complexity of the element of a DOM tree of the SVG scene is played back on the device via the complexity variable, and a maximum executable complexity of the element is played back on the device via the device complexity variable.

Abstract: Process for the telomerization of a conjugated diene, wherein the conjugated diene is reacted with a compound containing an active hydrogen atom and having a formula R?—H in the presence of a telomerization catalyst based on: (a) a source of group VIII metal, (b) a bidentate ligand wherein the bidentate ligand has the general formula I R1R2M1-R-M2R3R4??(I) wherein M1 and M2 are independently P, As or Sb; R1, R2, R3 and R4 independently represent a monovalent aliphatic group; or R1, R2 and M1 together and/or R3, R4 and M2 together independently represent an optionally substituted aliphatic cyclic group with at least 5 ring atoms, of which one is the M1 or M2 atom, respectively; R represents a bivalent organic bridging group; and novel bidentate diphosphines which can be used in this process.

Abstract: The invention is directed to a device for calibrating an optical detection channel for a two-dimensional, spatially dependent measurement of fluorescent or luminescent radiation in multi-specimen carriers. The invention provides a system for calibrating an optical detection channel for a two-dimensional, spatially dependent measurement of fluorescent or luminescent radiation in multi-specimen carriers permitting a highly accurate calibration of the spatial sensitivity distribution of the sensor array in the detection channel. The invention provides a plate-shaped housing, a luminescent foil inside the housing which is arranged parallel to the window so as to cover its surface, a power source and control units which are provided in the housing for controlling the luminescent foil, so that the luminescent foil can be controlled for homogeneous emission of luminescent light through the window of the housing in different intensity levels.

Abstract: The invention is directed to a device for calibrating an optical detection channel for a two-dimensional, spatially dependent measurement of fluorescent or luminescent radiation in multi-specimen carriers.