Abstract: The disclosed embodiments concern methods, apparatus, systems and computer program products for determining the presence or absence of repeat expansions of interest, including repeat expansions of repeat sequences that are medically significant. Some embodiments provide methods for identifying and calling medically relevant repeat expansions using anchored reads. An anchored read is a paired end read that is unaligned to a repeat sequence under consideration, but it is paired with an anchor read that is aligned to or near the repeat sequence. Some embodiments use both anchor and anchored reads to determine the presence or absence of the repeat expansions. System, apparatus, and computer program products are also provided for determining repeat expansion implementing the methods disclosed.

Abstract: The disclosure herein provides for transmitting data from an induction heating device to a receiver of an inductively heatable cooking vessel. The induction heating device may include a resonant circuit with an induction heating coil and a converter that may generate a control voltage (UA) from an AC mains voltage (UN) with a control frequency. The resonant circuit may be applied with a control voltage in order to generate an alternating magnetic field for heating the cooking vessel. The data to be transmitted to the receiver may be encoded using the the control frequency.

Abstract: An induction hob has a hob plate, a plurality of induction heating coils arranged under the hob plate and a plurality of sensor coils arranged under the hob plate. The induction heating coils are rectangular, wherein at least two induction heating coils are arranged one behind the other and at least three induction heating coils are arranged one next to the other. Two adjacent induction heating coils form an adjacent region with one another in which the two induction heating coils lie with their adjacent sides. At least one sensor coil is arranged in each adjacent region, wherein precisely a single sensor coil is provided in a spacing direction from the one induction heating coil to the adjacent induction heating coil.

Abstract: The present disclosure provides methods and systems for determining the presence or absence of aneuploidy in a fetus. In particular, the present disclosure provides noninvasive methods and systems for detecting the presence of fetal trisomy and other fetal chromosomal anomalies, paternity of a fetus and fetal genotype.

Abstract: An ultrasound transducer assembly of the present invention includes a flexible circuit to which an ultrasound transducer array and integrated circuitry are attached during fabrication of the ultrasound transducer assembly. The flexible circuit comprises a flexible substrate to which the integrated circuitry and transducer elements are attached while the flexible substrate is in a substantially flat shape. The flexible circuit further comprises electrically conductive lines that are deposited upon the flexible substrate. The electrically conductive lines transport electrical signals between the integrated circuitry and the transducer elements. After assembly, the flexible circuit is re-shapable into a final form such as, for example, a substantially cylindrical shape.

Abstract: This document discusses, among other things, a connector for an optical imaging probe that includes one or more optical fibers communicating light along the catheter. The device may use multiple sections for simpler manufacturing and ease of assembly during a medical procedure. Light energy to and from a distal minimally-invasive portion of the probe is coupled by the connector to external diagnostic or analytical instrumentation through an external instrumentation lead. Certain examples provide a self-aligning two-section optical catheter with beveled ends, which is formed by separating an optical cable assembly. Techniques for improving light coupling include using a lens between instrumentation lead and probe portions. Techniques for improving the mechanical alignment of a multi-optical fiber catheter include using a stop or a guide.

Abstract: Members calling card is described. In an embodiment, a call source initiates communication with a call-in service that then provides contact information via which the call source can obtain a members calling card to access, or continue accessing, the call-in service. A switch receives a communication from the call source that initiates use of the contact information and the switch establishes a communication link between the call source and a card provider such that the call source can obtain the members calling card. The members calling card is issued such that communication with the call-in service is charged on a telephone bill associated with the call source. The switch establishes a telephone-based communication link to enable communication between the call source and the call-in service where the communication is charged to the telephone bill associated with the call source.

Abstract: An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

Abstract: In an implementation of collect callback, a call-in service establishes a communication link with a call source, and initiates a collect callback option for the call source. A telecommunications switch can receive callback data from the call-in service and utilize the callback data to establish a collect call via a second communication link between the call source and the call-in service. A billing entity can receive a billing dispute from the call source that disputes charges for the collect call initiated by the call-in service and authorized by the call source. The billing entity can then communicatively link the call source to recorded data that corresponds to the collect call to which the charges apply where the recorded data includes a recording of at least a portion of the collect call to sustain the charges for the collect call.

Abstract: In an implementation of collect callback, a call-in service establishes a communication link with a call source, and initiates a collect callback option for the call source. A telecommunications switch receives callback data from the call-in service and utilizes the callback data to establish a collect call via a second communication link between the call source and the call-in service.

Abstract: An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

Abstract: The present invention comprises methods for fabricating an ultrasound transducer assembly having a flexible circuit. Preferably, the method comprises attaching an ultrasound transducer array and integrated circuitry to the flexible circuit during fabrication of the ultrasound transducer assembly while the flexible circuit is in a substantially flat shape. The contacts of the transducer elements are positioned on substantially the same plane such that electrical contact with signal and ground lines on the flexible circuit is established without the need for conductive bridges to physically remote electrodes.

Abstract: Collect callback is described. In an embodiment, a Web site associated with a call-in service provides that a call source can initiate a collect callback option to establish a communication link with the call-in service. A switch receives callback data corresponding to the call source via the Web site and utilizes the callback data to establish a collect call via the communication link between the call source and the call-in service.

Abstract: Collect callback for Web-based access is described. In an embodiment, a Web-based resource provides a collect callback option via which a call source can obtain an access code to access the Web-based resource. A switch receives callback data from the Web-based resources and utilizes the callback data to establish a collect call via a telephone-based communication link between the call source and an access code provider that provides the access code to the call source. In an alternate embodiment, the switch establishes the collect call between the call source and the switch which provides the access code to the call source.

Abstract: A flexible elongate member such as a pressure guide wire (1000) includes an electrical device such as a pressure sensor (1002). The pressure sensor (1002) is electrically connected to conductive bands (304), (306) and (308) located on electrical connector (300). The electrical connector is attached to core wire (602) and shaft or hypotube (704). The use of electrical connector (300) helps minimize the assembly time of pressure guide wire (1000), as well as minimize some of the assembly problems associated with prior art designs such as pressure guide wire (100).

Abstract: In an implementation of collect callback, a call-in service establishes a communication link with a caller and initiates a collect callback option for the caller. A switch receives callback data from the call-in service and utilizes the callback data to establish a collect call via a second communication link between the caller and the call-in service.

Abstract: The invention relates to a tool head with a spindle bearing arrangement The bearings (9, 10) of said arrangement rest with one of their bearing shells on a driven spindle (2) with a tool holding fixture (1). With their other bearing shell they interact with a housing (8) in such a manner that in at least one part (10) of the bearings (9, 10) the respective other bearing shell interacts with a sliding piece (11) which is slideable along the housing (8) in the one sliding direction and which locks the spindle (2) with the housing (8) in a locking position. In the other sliding direction, said sliding piece releases the spindle in a release position. The invention provides a universally useful tool head by the following configuration: The respective other bearing shell of the one part (10) of the bearings (9, 10) is at least partially enclosed by the sliding piece (11). Said sliding piece (11) is forced into the locking position with a predetermined contact force by a drive device.