Patents by Inventor Michael Edidin

Michael Edidin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for enhanced cellular selectivity using nanocarrier-associated ligands
    Patent number: 10034924
    Abstract: The presently disclosed subject matter provides methods and compositions for activation of clustered receptors on a target cell using nanocarrier-associated ligands, particularly methods and compositions for targeted activation of clustered receptors on antigen-experienced T cells using nanocarrier-associated antibodies.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: July 31, 2018
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Jonathan Powell, Ying-Chun Lo, Michael Edidin
  • METHODS AND COMPOSITIONS FOR ENHANCED CELLULAR SELECTIVITY USING NANOCARRIER-ASSOCIATED LIGANDS
    Publication number: 20160339091
    Abstract: The presently disclosed subject matter provides methods and compositions for activation of clustered receptors on a target cell using nanocarrier-associated ligands, particularly methods and compositions for targeted activation of clustered receptors on antigen-experienced T cells using nanocarrier-associated antibodies.
    Type: Application
    Filed: December 22, 2014
    Publication date: November 24, 2016
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: JONATHAN POWELL, YING-CHUN LO, MICHAEL EDIDIN
  • Protein label and drug delivery system
    Patent number: 5055561
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: November 1, 1989
    Date of Patent: October 8, 1991
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya
  • Protein label and drug delivery system
    Patent number: 4889916
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manfacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: December 26, 1989
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya
  • Protein label and drug delivery system
    Patent number: 4751286
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: November 19, 1985
    Date of Patent: June 14, 1988
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya