Abstract: A wearable device for detecting and/or measuring physiological information from a subject includes a housing, at least one optical emitter supported by the housing, at least one optical detector supported by the housing, a first light guide supported by the housing, a second light guide supported by the housing, a motion sensor supported by the housing, and a processor supported by the housing. The processor is configured to calculate footsteps, distinguish footsteps from heart beats, and to remove footstep motion artifacts from signals produced by the at least one optical detector. Also, the processor is configured to process signals produced by the at least one optical detector to determine subject heart rate and to produce integrity data about the subject heart rate. The process is further configured to generate a multiplexed output serial data string comprising the subject heart rate and the integrity data.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, a blood flow stimulator, and a processor configured to process signals from the PPG sensor to determine a signal-to-noise level of the signals. In response to a signal-to-noise level determination, the processor is configured to instruct the blood flow stimulator to increase blood perfusion at a location where the PPG sensor is attached to the subject. The signal-to-noise level determination may be a determination that the signal-to-noise level is below a threshold level. The blood flow stimulator may be a heating element or light source configured to heat the location of the subject.

Abstract: An ear-worn device includes a speaker, an optical emitter, an optical detector, a processor, and a housing configured to be positioned within an ear of a subject, wherein the housing encloses the speaker, optical emitter, optical detector, and processor. The housing includes at least one window that exposes the optical emitter and optical detector to the ear of the subject, and the housing includes at least one aperture through which sound from the speaker can pass. Light transmissive material is located between the optical emitter and the at least one window and is configured to deliver light emitted from the optical emitter to an ear region of the subject at one or more predetermined locations. Light transmissive material is positioned between the optical detector and the at least one window and is configured to collect light external to the housing and deliver the collected light to the optical detector.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, a blood flow stimulator, and a processor configured to process signals from the PPG sensor to determine a confidence score of the signals. In response to a signal-to-noise level determination, the processor is configured to instruct the blood flow stimulator to increase blood perfusion at a location where the PPG sensor is attached to the subject. The confidence score is an indication of how strongly the signals can be trusted.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, and at least one processor configured to process signals from the PPG sensor to determine heart rate and RR-interval (RRi) for the subject, and to determine a heart rate pattern for the subject over a period of time. The at least one processor is configured to change a sampling frequency of the PPG sensor for determining RRi in response to the determined heart rate pattern. The at least one processor is configured to reduce the sampling frequency of the PPG sensor in response to determining a pattern of heart rate below a threshold.

Abstract: Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to detect/measure physiological information from the subject, and a processor configured to process the physiological information to detect subject stress, and to determine an origin of the subject stress. The processor can determine the origin of the subject stress by increasing a sampling rate of the PPG sensor to collect higher acuity physiological information. The processor also can determine the origin of the subject stress by processing data from the PPG sensor to determine whether the subject is likely to have atrial fibrillation. In response to determining that the subject is likely to have atrial fibrillation, the processor can increase a frequency of pulsing of an optical emitter of the PPG sensor and/or increase a sampling rate of the PPG sensor to collect higher acuity data for diagnosing that atrial fibrillation is truly occurring.

Abstract: An earpiece monitor configured to be worn by a subject includes a battery, an earpiece fitting configured to be inserted within an ear canal of an ear of the subject, a reflective pulse oximeter configured to measure pulse rate and pulse intensity of the subject, a motion sensor configured to monitor footsteps and head motion of the subject, a digital memory for storing at least one algorithm, and a processor configured to process signals from the reflective pulse oximeter and the motion sensor using the at least one algorithm to generate as assessment of a health state of the subject. The earpiece fitting is configured to transmit sound to the inner ear or eardrum of the subject. The assessment of the health state of the subject may include an assessment of subject physiological stress and/or an assessment of overall subject health.

Abstract: A system for monitoring the cardiopulmonary functioning of a person includes a remote terminal and a sensor module configured to be worn by the person. The sensor module includes at least one physiological sensor configured to sense the following types of physiological information generated by the person: pulse rate, blood flow, and blood pressure; at least one signal processor configured to process signals generated by the at least one physiological sensor; and at least one transmitter responsive to the at least one signal processor that is configured to transmit at least one signal to the at least one remote terminal. The at least one signal processor is configured to focus processing resources on one of the types of physiological information in response to a specified preference by the person.

Abstract: A wearable device collects a plurality of photoplethysmography (PPG) waveforms from a PPG sensor in the wearable device and collects inertial data associated with subject motion from an inertial sensor in the wearable device. The wearable device processes the inertial data in an assessment processor of the wearable device to determine a data integrity of the plurality of PPG waveforms and, responsive to the determined data integrity, processes the plurality of PPG waveforms in the assessment processor using a neural network comprising thousands of coefficients to generate an assessment of the subject blood pressure.

Abstract: An earpiece module includes a physiological sensor, an external energy sensor, a transceiver, a communication module, a data storage component, and a power source. The communication module includes a microphone, a speaker, and a signal processor. The signal processor processes audio information received from a remote source via the transceiver and communicates the processed audio information to a subject via the speaker. The signal processor processes information in real time from the physiological sensor and the external energy sensor, and the signal processor provides biofeedback to the subject based on signals produced by the physiological sensor. The data storage component includes a plurality of algorithms. At least one algorithm focuses processing resources on extracting physiological information from the physiological sensor, at least one algorithm is configured to be modified or uploaded wirelessly via the transceiver, and at least one algorithm is a compression/decompression (CODEC) algorithm.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, and at least one processor configured to process signals from the PPG sensor to determine heart rate and RR-interval (RRi) for the subject, and to determine a heart rate pattern for the subject over a period of time. The at least one processor is configured to change a sampling frequency of the PPG sensor for determining RRi in response to the determined heart rate pattern. The at least one processor is configured to reduce the sampling frequency of the PPG sensor in response to determining a pattern of heart rate below a threshold.

Abstract: An optical sensor module includes a housing, first and second optical emitters within the housing, and an optical detector within the housing that is positioned between the first and second optical emitters. The housing includes respective first and second windows of optically transparent material that overlie the first and second optical emitters, and also includes a third window of optically transparent material that overlies the optical detector. The third window includes opposite first and second ends and opposite first and second sides, and at least one of the first and second sides is curved inwardly. Both of the first and second sides of the third window may be curved inwardly such that the third window has an hourglass shape.

Abstract: A hearing aid includes a speaker driver, an optical source secured directly to the speaker driver, an optical detector secured directly to the speaker driver, a first light guide extending outwardly from the optical source and in optical communication with the optical source, and a second light guide extending outwardly from the optical detector and in optical communication with the optical detector. The first light guide is configured to deliver light from the optical source into an ear region of the subject via a distal end thereof, and the second light guide is configured to collect light from the ear region via a distal end thereof and deliver collected light to the optical detector. The hearing aid may include at least one signal processor configured to process signals produced by the optical detector, and at least one of the following: an accelerometer, a humidity sensor, an altimeter, a temperature sensor.

Abstract: Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

Abstract: A headset includes a housing defining an audio cavity, a speaker located within the audio cavity, and first and second sensor modules within the housing in spaced-apart, angled relationship to each other. The housing includes an aperture through which sound from the speaker can pass, and the first and second sensor modules are on opposing sides of a direction from the speaker to the aperture. The first sensor module is configured to direct electromagnetic radiation at a first target region of an ear of a person wearing the headset and to detect a first energy response signal therefrom that is associated with one or more physiological metrics of the subject, and the second sensor module is configured to direct electromagnetic radiation at a second target region of the ear and to detect a second energy response signal therefrom that is associated with the one or more physiological metrics.

Abstract: A wearable device collects a plurality of photoplethysmography (PPG) waveforms from a PPG sensor in the wearable device and collects inertial data associated with subject motion from an inertial sensor in the wearable device. The wearable device processes the inertial data in an assessment processor of the wearable device to determine a data integrity of the plurality of PPG waveforms and, responsive to the determined data integrity, processes the plurality of PPG waveforms in the assessment processor using a neural network comprising thousands of coefficients to generate an assessment of the subject blood pressure.

Abstract: Apparatus, systems, and methods for measuring environmental exposure and physiological response thereto are provided. A monitoring apparatus worn by a subject includes a physiological sensor that detects physiological information from the subject, an environmental exposure sensor that detects at least one airborne analyte in a vicinity of the subject, and a processor. The processor processes signals produced by the environmental exposure sensor and calculates a volumetric concentration of the least one airborne analyte. In addition, the processor process signals produced by the at least one physiological sensor to determine a physiological response of the subject to the at least one airborne analyte. The apparatus also includes a motion sensor and the processor calculates a distance traveled by the subject via signals produced by the motion sensor and calculates a volume of air to which the subject has been exposed using the distance traveled by the subject.

Abstract: Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

Abstract: An apparatus adapted to be worn at or near at least one ear of a subject includes a battery, a reflective pulse oximeter, a motion sensor, an analog-to-digital convertor configured to convert analog signals from the reflective pulse oximeter and the motion sensor into digitized information, a speaker, a digital memory device configured to store at least one algorithm for signal processing, a transceiver, and a signal processor. The signal processor is configured to process data from the reflective pulse oximeter to monitor cardiopulmonary functioning of the subject, process data from the motion sensor to monitor head and body motion, execute the at least one algorithm for assessing a health state of a subject, poll the reflective pulse oximeter and the motion sensor at certain time intervals to extend life of the battery, and process digital audio information into analog sounds to be presented to the subject via the speaker.