Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: A framework and graphical user interface for sharing, comparing, and displaying resource usage data provide for the ability to construct an extensible framework for configuring a graphical user interface (GUI) containing resource usage data pertaining to one or more entities. In various embodiments, the framework enables competitions and comparisons, event tagging, carbon offsetting, or any combination thereof. The framework also makes the GUI available by various means, including Internet distribution. The GUI may take the form of websites, standalone applications, desktop widgets, blog or social networking applications, and the like.

Abstract: Resource usage data is automatically collected for an individual, household, family, organization, or other entity. The collected data is transmitted to a central repository, where it is stored and compared with real-time and/or historical usage data by that same entity and/or with data from other sources. Graphical, interactive displays and reports of resource usage data are then made available. These displays can include comparisons with data representing any or all of community averages, specific entities, historical use, representative similarly-situated entities, and the like. Resource usage data can be made available within a social networking context, published, and/or selectively shared with other entities.

Abstract: A removable load bearing textile clamp including a locking clamp portion configured to accept an internally positioned rod such that a textile sheet can be led around the rod and positioned inside the clamp and secured by closing the clamp and engaging the locking mechanism.

Abstract: An invention where a removable load bearing textile clamp comprised of a locking clamp portion configured to accept an internally positioned rod such that a textile sheet can be led around the rod and positioned inside the clamp and secured by closing the clamp and engaging the locking mechanism.

Abstract: Resource usage data is automatically collected for an individual, house-hold, family, organization, or other entity. The collected data is transmitted to a central repository, where it is stored and compared with real-time and/or historical usage data by that same entity and/or with data from other sources. Graphical, interactive displays and reports of resource usage data are then made available. These displays can include comparisons with data representing any or all of community averages, specific entities, historical use, representative similarly-situated entities, and the like. Resource usage data can be made available within a social networking context, published, and/or selectively shared with other entities.