Patents by Inventor Michael Edward Werner

Michael Edward Werner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200002667
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: February 12, 2019
    Publication date: January 2, 2020
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Patent number: 10246678
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 2, 2019
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Publication number: 20170015974
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 27, 2016
    Publication date: January 19, 2017
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • Publication number: 20150110753
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: August 8, 2014
    Publication date: April 23, 2015
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • Patent number: 8802081
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 12, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Publication number: 20140017165
    Abstract: This invention relates generally to the discovery of novel nanoparticles for delivery of DNA double-stranded break (DSB) repair enzyme inhibitors such as wortmannin or wortmannin analogues. In one embodiment, these nanoparticles comprise a polylactide polyglycolide (PLGA) copolymer and a polyethylene glycol (PEG). In addition methods of treatment and methods of enhancing radiation treatments are also provided.
    Type: Application
    Filed: January 11, 2012
    Publication date: January 16, 2014
    Inventors: Zhuang Wang, Michael Edward Pacold, Michael Edward Werner, Shrirang Karve
  • Publication number: 20130195811
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 1, 2011
    Publication date: August 1, 2013
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Ried, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Publication number: 20120259153
    Abstract: Delivery systems adapted for implementation during a brachytherapy procedure are provided. The delivery system includes a plurality of brachytherapy seeds and a plurality of spacers. Each spacer is formed of a matrix material carrying a plurality of microparticles and/or nanoparticles. The microparticles and/or nanoparticles carry an agent and are biodegradable and/or biocompatible. The brachytherapy seeds and the spacers are configured to be delivered to a target site. Associated methods are also provided.
    Type: Application
    Filed: October 20, 2010
    Publication date: October 11, 2012
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Zhuang Wang, Michael Edward Werner, James Donald Byrne, Ronald Chingyun Chen, Shrirang Shrikant Karve, Joseph DeSimone