Abstract: The invention comprises a differential air pressure exercise system, comprising: a base; a pair of uprights on the base dividing the base into a front portion and a rear portion; a bulkhead extending between and vertically moveable relative to the uprights; a right arm and a left arm attached to the bulkhead extending from the bulkhead towards the base rear portion; a chamber support frame coupling element on the right arm and on the left arm; a hinge coupled to the bulkhead between the left and right arms; a chamber support frame extending between the left and right arms and coupled to the hinge to move between an engaged condition and a lowered condition.

Abstract: Described herein are systems, devices, and methods for generating and delivering an inhalable vapor or aerosol. In some embodiments, the systems, devices, and methods described herein are used to generate and deliver a vapor or aerosol containing tobacco for use in, for example, traditional smoking or, for example, to deliver a smoking cessation therapy. In some embodiments, the systems, devices, and methods described herein are used for generating and delivering a vapor or aerosol comprising a medicament. For example, in some embodiments, the systems, devices, and methods described herein are used to deliver an inhalable medicament to the lungs of a patient.

Abstract: Computerized methods and apparatuses, including computer program products, for guided workflow processing include a server computing device which determines a guided workflow transaction path based upon input received from a first client device. The server initiates a transaction based upon the transaction path, including capturing data elements associated with a user of a second client device. The server stores the captured data elements, including a transaction identification token and a state of the transaction path. The server receives a request to continue the transaction from the second client device and retrieves the data elements. The server generates a user interface form based upon the state of the transaction path and displays the user interface form on the second client device. The server processes the transaction based upon input received from the second client device via the user interface form.

Abstract: A chemical synthesis plant comprising: one or more reactors configured for producing, from one or more reactants, a process stream comprising at least one chemical product; a feed preparation system configured to prepare one or more feed streams comprising one or more of the one or more reactants for introduction into the one or more reactors; and/or a product purification system configured to separate the at least one chemical product from reaction byproducts, unreacted reactants, or a combination thereof within the process stream, wherein the chemical synthesis plant is configured such that a majority of the net energy needed for heating, cooling, compressing, or a combination thereof utilized via the one or more reactors, the feed preparation system, the product purification system, or a combination thereof is provided from a non-carbon based energy source, from a renewable energy source, and/or from electricity.

Abstract: Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

Abstract: Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.

Abstract: A turbine system includes a foam generating assembly having an in situ foam generating device at least partially positioned within the fluid passageway of the turbine engine, such that the in situ foam generating device is configured to generate foam within the fluid passageway of the turbine engine.

Abstract: A drink and mist bottle cap is detachably attachable to a bottle to enable a person to produce a mist from a pump and mist nozzle and also drink from a drink spout. A drinking spout has a drink spout cap that is detachably attachable over the drinking spout to seal the liquid contents within the bottle when not drinking form the bottle. The drink and mist bottle cap may also have an anti-backwash valve that is configured to prevent backwash from flowing back into the interior of the bottle and an ultraviolet light configured to produce a disinfecting ultraviolet light within the bottle, and a pressure relief valve to allow pressure equalization when there is a pressure differential between the interior of the bottle and the exterior of the bottle.

Abstract: The present disclosure is generally directed toward a pontic material that is pliable and easily moldable, possesses a higher tear resistance to resist fragmenting and thus is long lasting, can be pigmented to achieve a good color match to adjacent teeth, and be fashioned into a pontic by the patient at home so as to free the orthodontist and their staff from having to do this purely aesthetic and time-consuming procedure. In addition, the pontic material of the present disclosure is typically permanently pliable so that an untrained person such as a patient would have unlimited time to make corrections to the shape of the material to obtain an aesthetically pleasing shape and typically do so without the use of tools or any specialized tools or equipment.

Abstract: A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, a blood flow stimulator, and a processor configured to process signals from the PPG sensor to determine a confidence score of the signals. In response to a signal-to-noise level determination, the processor is configured to instruct the blood flow stimulator to increase blood perfusion at a location where the PPG sensor is attached to the subject. The confidence score is an indication of how strongly the signals can be trusted.

Abstract: An olefin synthesis plant comprising: a feed pretreatment section configured to pretreat a feed stream; a pyrolysis section comprising one or more pyrolysis reactors configured to crack hydrocarbons in the feed stream in the presence of a diluent to produce a cracked gas stream; a primary fractionation and compression section configured to provide heat recovery from and quenching of the cracked gas stream; remove a component from the cracked gas stream; and compress the cracked gas stream, thus providing a compressed cracked gas stream; and/or a product separation section configured to separate a product olefin stream from the compressed cracked gas stream, wherein the olefin synthesis plant is configured such that, relative to a conventional olefin synthesis plant, more of the energy and/or the net energy required by the olefin synthesis plant and/or one or more sections thereof, is provided by a non-carbon based and/or renewable energy source and/or electricity.

Abstract: An all-solid secondary battery including: a cathode layer including a cathode active material layer; an anode layer; and a solid electrolyte layer between the cathode layer and the anode layer, and the solid electrolyte layer including a solid electrolyte, wherein the anode layer includes an anode current collector, a first anode active material layer in contact with the solid electrolyte layer, and a second anode active material layer between the anode current collector and the first anode active material layer, wherein the first anode active material layer is a lithium-containing first metal layer, wherein the second anode active material layer includes a carbon-containing anode active material or a carbon-containing anode active material and a second metal, and wherein a surface of the solid electrolyte layer adjacent to the first anode active material layer has a porosity of 40 percent or less.

Abstract: A chemical synthesis plant comprising: one or more reactors configured for producing, from one or more reactants, a process stream comprising at least one chemical product; a feed preparation system configured to prepare one or more feed streams comprising one or more of the one or more reactants for introduction into the one or more reactors; and/or a product purification system configured to separate the at least one chemical product from reaction byproducts, unreacted reactants, or a combination thereof within the process stream, wherein the chemical synthesis plant is configured such that a majority of the net energy needed for heating, cooling, compressing, or a combination thereof utilized via the one or more reactors, the feed preparation system, the product purification system, or a combination thereof is provided from a noncarbon based energy source, from a renewable energy source, and/or from electricity.

Abstract: Disclosed herein are methods of treating cancer, said methods comprising administering a therapeutically effective amount of erdafitinib to a patient who has been diagnosed with cancer and who harbors at least one fibroblast growth factor receptor (FGFR) fusion selected from FGFR2-CCDC102A, FGFR2-CCDC147, FGFR2-ENOX1, FGFR2-GPHN, FGFR2-LCN10, FGFR2-PDE3A, FGFR2-RANBP2, FGFR3-ENOX1, FGFR3-TMEM247, IGSF3-FGFR1, RHPN2-FGFR1, and RRM2B-FGFR2.

Abstract: A computing system including a processor configured to receive a stabilizer circuit specification of a stabilizer circuit that includes one or more elementary operations. The elementary operations are each selected from the group consisting of an allocation of one or more qubits in a stabilizer state, an allocation of one or more random classical bits, a Clifford unitary, a Pauli unitary conditional on respective parities of measurement outcomes and/or respective parities of the random classical bits, a joint multi-qubit Pauli measurement, and a destructive one-qubit Pauli measurement. The processor is further configured to compute a standardized stabilizer instrument specification of a stabilizer instrument based at least in part on the stabilizer circuit specification. The standardized stabilizer instrument specification includes an input Clifford unitary, an output Clifford unitary, and a plurality of bit matrices.

Abstract: A cathode configured for a solid-state battery includes a body having grains of inorganic material sintered to one another, wherein the grains comprise lithium. A thickness of the body is from 3 ?m to 100 ?m. The first major surface and the second major surface have an unpolished granular profile such that the profile includes grains protruding outward from the respective major surface with a height of at least 25 nm and no more than 150 ?m relative to recessed portions of the respective major surface at boundaries between the respective grains.

Abstract: A dental composition for the desensitization and covering of an area of a human tooth comprising a finger malleable base material made up of a product consisting of either: one or more hydrocarbon-based waxes, possibly with either or both of an organic filler and an inorganic filler, an uncured, uncross linked silicone high consistency rubber base; or a hydrophobic water insoluble solid material that is malleable at 37° C. or lower and safe for a human oral environment. The dental composition also includes a combination of dry, powdered materials dispersed on a tooth-engaging surface of the finger malleable base material. The combination of dry, powdered materials comprises a water-soluble polymeric adhesive and at least one dental tubule blocking agent or hypersensitivity desensitization ingredient.

Abstract: An electrical socket includes a socket body defining a longitudinal axis and including a plurality of contact beams that are spaced from each other and that extend between a first end section and a second end section, the plurality of contact beams including a middle section positioned between the first end section and the second end section. Each of the plurality of contact beams has a contour extending between the first end section and the second end section such that a cross-section of the middle section of the plurality of contact beams taken in a plane oriented perpendicular to the longitudinal axis has a curved shape extending toward an interior of the socket body. The socket body is configured to receive a mating pin. The middle section comprises an inner contact area configured to contact the mating pin.

Abstract: Solid-state electrochemical cells are disclosed. In examples, the cell comprises a sintered cathode layer, an electrolyte layer, an anode layer arranged on at least part of the electrolyte layer, an anode current collector, and a cathode current collector. The sintered cathode layer comprises side surfaces having portions which extend in planes oblique to the plane in which the top and/or bottom surfaces of the sintered cathode layer extend. The electrolyte layer is arranged on at least one of these portions; the cathode current collector is arranged on at least another of these portions.