Abstract: A device for reinforcing a femoral neck bone, the femoral neck bone including a cortical bone region and a cancellous bone region, the device including a support structure having an outer surface and including a portion having one or more bores, the one or more bores adapted to allow filler material to be released therefrom to enter directly into the cancellous bone.

Abstract: A computer-implemented method includes generating a computer user interface to accept physical counts of items associated with events recorded by a collection of electronic devices. A first user interface screen includes a list of a first subset of electronic devices from the collection of electronic devices and for each electronic device in the first subset, a field indicating a physical count of items associated with the electronic device. A second user interface screen includes input fields for receiving physical counts of the items and a menu of a second subset of the collection of electronic devices, wherein none of the electronic devices in the second subset are in the first subset such that it is impossible for a user to select an electronic device displayed on the first screen.

Abstract: A fault tolerant computer system and method are disclosed. The system may include a plurality of CPU nodes, each including: a processor and a memory; at least two IO domains, wherein at least one of the IO domains is designated an active IO domain performing communication functions for the active CPU nodes; and a switching fabric connecting each CPU node to each IO domain. One CPU node is designated a standby CPU node and the remainder are designated as active CPU nodes. If a failure, a beginning of a failure, or a predicted failure occurs in an active node, the state and memory of the active CPU node are transferred to the standby CPU node which becomes the new active CPU node. If a failure occurs in an active IO domain, the communication functions performed by the failing active IO domain are transferred to the other IO domain.

Abstract: A device for reinforcing a femoral neck bone, the femoral neck bone including a cortical bone region and a cancellous bone region, the device including a support structure having an outer surface and including a portion having one or more bores, the one or more bores adapted to allow filler material to be released therefrom to enter directly into the cancellous bone.

Abstract: A pair of tongs, comprises: first and second arms, each arm having a gripping end and a pivot end. A hinge pivotably joins the first and second arms at the pivot ends thereof. A spring is coupled to each of the first and second arms, the spring being biased to urge the first and second arms apart, from a first, closed position, to a second, open, position. A releasable lock locks the first and second arms in the closed position, the releasable lock being operable by a single hand of a user.

Abstract: A method of reinforcing a femoral neck comprises creating a bore proximate to at least one of a Ward's triangle and a greater trochanter, creating at least one cavity in a cancellous bone region of the femoral neck, inserting a substantially collapsed support structure through the bore and into the at least one cavity, expanding the support structure, and allowing at least a portion of the load from the femoral neck bone to be transferred to the support structure. The support structure compresses at least a portion of the cancellous bone upon expansion. A cavity created by the expansion is adapted to receive a filler material such as, but not limited to, bone cement.

Abstract: Grinders, analyzers, and related technologies are described herein. The grinders can hold foodstuff that is periodically ground. The analyzers can analyze the foodstuff to determine information about the state of the foodstuff. Algorithms can be used to determine how to process the foodstuff, how to use the foodstuff, and/or when to discard the foodstuff. The grinder can be a portable, rechargeable electric coffee grinder configured to monitor the freshness of the coffee beans. When coffee beans become stale, they can be discarded and the coffee grinder can be refilled with fresh coffee beans.

Abstract: A travel receptacle comprising a receptacle for holding a liquid and a lid for selectively closing the receptacle. The lid includes a first piece for engaging the top of the receptacle, the first piece having an impermeable portion which blocks the passage of the liquid therethrough and a first opening for allowing the passage of the liquid therethrough; and a second piece having an impermeable portion which blocks the passage of the liquid therethrough and a second opening for allowing the passage of the liquid therethrough. At least one of the first piece and the second piece is movable with respect to the other, between an open position in which the first and second openings align to allow passage of the liquid therethrough and a closed position in which the first and second openings are not aligned, thereby blocking passage of the liquid.

Abstract: A device for accessing and distending a joint comprises a distraction structure having a generally tapered distal portion adapted to penetrate a tissue region and create an access space within a joint. The distraction structure also includes a lumen extending from a proximal surface to a distal portion. The device further includes a distention structure deployable through the lumen and adapted to exert a force between a first joint surface and a second joint surface and create a working space. The distention structure may, in some embodiments, include an elongate member having a proximal end, a distal end, and a lumen extending along at least a portion of the length of the elongate member, a first expandable region deployable from a first substantially collapsed position to a second substantially expanded position, the first expandable region adapted to exert a force between the first joint surface from the second joint surface.

Abstract: The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.

Abstract: A method of reinforcing a femoral neck comprises creating a bore proximate to at least one of a Ward's triangle and a greater trochanter, creating at least one cavity in a cancellous bone region of the femoral neck, inserting a substantially collapsed support structure through the bore and into the at least one cavity, expanding the support structure, and allowing at least a portion of the load from the femoral neck. bone to he transferred to the support structure. The support structure compresses at least a portion of the cancellous bone upon expansion. A cavity created by the expansion is adapted to receive a filler material such as, but not limited to, bone cement.

Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.

Abstract: The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.

Abstract: A method of reinforcing a femoral neck comprises creating a bore proximate to at least one of a Ward's triangle and a greater trochanter, creating at least one cavity in a cancellous bone region of the femoral neck, inserting a substantially collapsed support structure through the bore and into the at least one cavity, expanding the support structure, and allowing at least a portion of the load from the femoral neck bone to be transferred to the support structure. The support structure compresses at least a portion of the cancellous bone upon expansion. A cavity created by the expansion is adapted to receive a filler material such as, but not limited to, bone cement.

Abstract: A method of reinforcing a femoral neck comprises creating a bore proximate to at least one of a Ward's triangle and a greater trochanter, creating at least one cavity in a cancellous bone region of the femoral neck, inserting a substantially collapsed support structure through the bore and into the at least one cavity, expanding the support structure, and allowing at least a portion of the load from the femoral neck bone to be transferred to the support structure. The support structure compresses at least a portion of the cancellous bone upon expansion. A cavity created by the expansion is adapted to receive a filler material such as, but not limited to, bone cement.

Abstract: A method of reinforcing a femoral neck comprises creating a bore proximate to at least one of a Ward's triangle and a greater trochanter, creating at least one cavity in a cancellous bone region of the femoral neck, inserting a substantially collapsed support structure through the bore and into the at least one cavity, expanding the support structure, and allowing at least a portion of the load from the femoral neck bone to be transferred to the support structure. The support structure compresses at least a portion of the cancellous bone upon expansion. A cavity created by the expansion is adapted to receive a filler material such as, but not limited to, bone cement.

Abstract: A device for accessing and distending a joint comprises a distraction structure having a generally tapered distal portion adapted to penetrate a tissue region and create an access space within a joint. The distraction structure also includes a lumen extending from a proximal surface to a distal portion. The device further includes a distention structure deployable through the lumen and adapted to exert a force between a first joint surface and a second joint surface and create a working space. The distention structure may, in some embodiments, include an elongate member having a proximal end, a distal end, and a lumen extending along at least a portion of the length of the elongate member, a first expandable region deployable from a first substantially collapsed position to a second substantially expanded position, the first expandable region adapted to exert a force between the first joint surface from the second joint surface.

Abstract: A device for accessing and distending a joint comprises a distraction structure having a generally tapered distal portion adapted to penetrate a tissue region and create an access space within a joint. The distraction structure also includes a lumen extending from a proximal surface to a distal portion. The device further includes a distention structure deployable through the lumen and adapted to exert a force between a first joint surface and a second joint surface and create a working space. The distention structure may, in some embodiments, include an elongate member having a proximal end, a distal end, and a lumen extending along at least a portion of the length of the elongate member, a first expandable region deployable from a first substantially collapsed position to a second substantially expanded position, the first expandable region adapted to exert a force between the first joint surface from the second joint surface.

Abstract: Methods are described for reducing cytoskeletal rearrangement and intercellular gap formation by contacting cells with an aminoalkyl glucosaminide phosphate. In particular, the methods can be used to reduce actin cytoskeletal rearrangement and/or intracellular gap formation related to ischemic or ischemia-reperfusion events and to alleviate diseases or conditions related to increased actin cytoskeletal rearrangement.