Abstract: We have disclosed a modular personal network (MPN) that includes multiple devices that may be worn, carried, or used in close proximity to a user. The devices communicate wirelessly. Functions of the MPN may be modified by adding or removing components. The MPN may communicate with a personal computer. General purpose devices may include a control unit, a display, a user input, and an audio output. The MPN may provide a variety of functions, including time, communication, entertainment, organization, guidance, athletic, medical, travel, outdoors, identity, security, and military.

Abstract: The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, or are prodrugs thereof, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis and cancer.

Abstract: The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.

Abstract: The invention provides certain phenyl carboxamide-containing compounds of the Formula (I); or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.

Abstract: The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.

Abstract: One or more systems, methods, or computer program products can include receiving an echo data set including information representative of an echo sensed by a transducer, provided at least in part by one or more actual targets included in a region of interest. The region of interest can be modeled, including selecting or generating an array manifold matrix including information corresponding to any one or more candidate targets. The weights of the candidate targets can be determined using the array manifold matrix and the echo data set, including minimizing an argument of a function modeling the weights of the candidate targets. In an example, the echo data set can be dithered, such as by adding a specified dithering signal.

Abstract: We have disclosed a system for sharing information about a first individual who has engaged or is engaging in a first physical activity. The system may include a first portable performance monitoring system that is capable of being carried with the first individual during the first physical activity. The first portable performance monitoring system may include a first processor configured to determine first performance information for the first individual and a transmitter configured to transmit the first performance information. The system may also include a second portable performance monitoring system that is capable of being carried with a second individual during a second physical activity. The second portable performance monitoring system may include a receiver configured to receive the first performance information and a second processor configured to generate display data based on the first performance information.

Abstract: We have disclosed a modular personal network (MPN) that includes multiple devices that may be worn, carried, or used in close proximity to a user. The devices communicate wirelessly. Functions of the MPN may be modified by adding or removing components. The MPN may communicate with a personal computer. General purpose devices may include a control unit, a display, a user input, and an audio output. The MPN may provide a variety of functions, including time, communication, entertainment, organization, guidance, athletic, medical, travel, outdoors, identity, security, and military.

Abstract: The disclosure relates generally to mold compositions and methods of molding and the articles so molded. More specifically, the disclosure relates to mold compositions, intrinsic facecoat compositions, and methods for casting titanium-containing articles, and the titanium-containing articles so molded, where the mold comprises calcium hexaluminate.

Abstract: Crucible compositions and methods of using the crucible compositions to melt titanium and titanium alloys. More specifically, crucible compositions having extrinsic facecoats comprising a rare earth oxide that are effective for melting titanium and titanium alloys for use in casting titanium-containing articles. Further embodiments are titanium-containing articles made from the titanium and titanium alloys melted in the crucible compositions. Another embodiment is a crucible curing device and methods of use thereof.

Abstract: We have disclosed systems and methods for monitoring an individual's performance during a physical activity. The methods may include using a first component and second component each configured to be worn or carried by the individual during a physical activity. The methods may include the first component communicating wirelessly with the second component over a personal area network during the physical activity, the first component determining that the second component has ceased communication with the first component during the physical activity, and the first component adapting a function in response to determining that the second component has ceased communication with the first component.

Abstract: The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.

Abstract: A text message paging and ordering system utilizes a dedicated or shared short code to enable an establishment, such as a restaurant, to send pages to mobile communication devices, such as a mobile phone. Transmitted text messages sent from the establishment are associated with a short code, which allows the mobile communication device in receipt of the text message to send reply messages back to the establishment associated with the short code. As such, this provides a wireless carrier approved medium that reliably and readily enables an establishment to have two-way text communication with a customer or client to facilitate paging functions as well as ordering functions.

Abstract: The disclosure relates generally to mold compositions comprising calcium aluminate and calcium titanate. The disclosure also relates to methods of molding and the articles so molded using the mold compositions. More specifically, the disclosure relates to calcium aluminate/calcium titanate mold compositions and methods for casting titanium-containing articles, and the titanium-containing articles so molded.

Abstract: We have disclosed a data transfer system that includes athletic equipment and at least two individual network components. A first individual network component is engaged with athletic equipment and is configured to transmit data to a remote component. A second individual network component is configured to receive data from a remote component. A second individual network component includes at least one of a display device and an audio output device. Data transmitted may include user identity and performance data and route data.

Abstract: The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.

Abstract: We have disclosed devices and methods for monitoring an individual's performance during a physical activity. The devices may include multiple elements such as a mount adapted to releasably secure the device to the individual's wrist during the physical activity, a heart rate sensor coupled to the mount and adapted to obtain heart rate data during the physical activity, a satellite positioning system receiver coupled to the mount and adapted to obtain position data during the physical activity, an acceleration sensor coupled to the mount and adapted to obtain acceleration data during the physical activity, and an output coupled to the mount and adapted to output performance information to the individual during the physical activity.

Abstract: We have disclosed systems and methods for providing outputs to an individual during a physical activity. The methods may include generating performance data based on an individual's performance during the physical activity, providing a first output based on performance data to the individual during the physical activity via a first output device, determining that a second output based on the performance data should be provided to the individual via a second output device that is different than the first output device, and providing the second output to the individual during the physical activity via the second output device.

Abstract: The present disclosure relates to a titanium-containing article casting mold composition comprising calcium aluminate and an X-ray or Neutron-ray detectable element. Furthermore, present embodiments teach a method for detecting sub-surface ceramic inclusions in a titanium or titanium alloy casting by combining calcium aluminate, an element more radiographically dense than the calcium aluminate, and a liquid to form a slurry; forming a mold having the calcium aluminate and the radiographically dense element from the slurry; introducing a titanium aluminide-containing metal to the radiographically dense element-bearing mold; solidifying said titanium aluminide-containing metal to form an article in the mold; removing the solidified titanium aluminide-containing metal article from said mold; subjecting the solidified titanium aluminide-containing article to radiographic inspection to provide a radiograph; and examining said radiograph for the presence of the radiographically dense element on or in the article.