Patents by Inventor Michael Eric Benz

Michael Eric Benz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8822546
    Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: September 2, 2014
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Christopher M. Hobot, Phillip Edward McDonald, Lian Leon Luo, John Kramer
  • Publication number: 20120149864
    Abstract: Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable.
    Type: Application
    Filed: February 14, 2012
    Publication date: June 14, 2012
    Applicant: Medtronics, Inc.
    Inventors: Julie A. Alkatout, Michael Eric Benz, Randall V. Sparer
  • Patent number: 8133968
    Abstract: Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: March 13, 2012
    Assignee: Medtronic, Inc.
    Inventors: Julie A. Alkatout, Michael Eric Benz, Randall V. Sparer
  • Publication number: 20110082275
    Abstract: Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 7, 2011
    Applicant: Medtronic, Inc.
    Inventors: Julie A. Alkatout, Michael Eric Benz, Randall V. Sparer
  • Publication number: 20110082266
    Abstract: The invention describes poly(ortho ester) polymers that include at least one therapeutic compound in the polymer backbone. The therapeutic compound includes at least one phenol residue and an aliphatic alcohol residue or two or more phenolic residues.
    Type: Application
    Filed: April 23, 2010
    Publication date: April 7, 2011
    Inventors: Michael Eric Benz, Erica M. TenBroek, Lian Leon Luo
  • Publication number: 20110065809
    Abstract: Methods for preparing polymers from multifunctional azides and multifunctional azide-reactants are described in the present disclosure. Exemplary multifunctional azide-reactants include multifunctional alkynes and/or multifunctional ?-phosphine esters. In certain embodiments, such polymers can be prepared in vivo. Such polymers can be useful in a wide variety of biomedical applications.
    Type: Application
    Filed: September 15, 2009
    Publication date: March 17, 2011
    Applicant: Medtronic, Inc.
    Inventors: Michael Eric Benz, Lian Leon Luo, Metasebia T. Munie
  • Patent number: 7875697
    Abstract: Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: January 25, 2011
    Assignee: Medtronic, Inc.
    Inventors: Julie A. Alkatout, Michael Eric Benz, Randall V. Sparer
  • Publication number: 20100255051
    Abstract: Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable.
    Type: Application
    Filed: June 18, 2010
    Publication date: October 7, 2010
    Inventors: Michael Eric Benz, Lian Leon Luo
  • Publication number: 20100240852
    Abstract: Heteroatom-containing polymers such as polyketals, and methods of making and using such heteroatom-containing polymers are disclosed herein. The heteroatom-containing polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the heteroatom-containing polymers are polyketals that are biodegradable.
    Type: Application
    Filed: March 22, 2010
    Publication date: September 23, 2010
    Applicant: Medtronic, Inc.
    Inventors: Lian Leon Luo, Michael Eric Benz
  • Patent number: 7741375
    Abstract: Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: June 22, 2010
    Assignee: Medtronic, Inc
    Inventors: Michael Eric Benz, Lian Leon Luo
  • Publication number: 20100137369
    Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.
    Type: Application
    Filed: December 1, 2008
    Publication date: June 3, 2010
    Applicant: Medtronic, Inc.
    Inventors: Michael Eric BENZ, Christopher M. Hobot, Phillip Edward McDonald, Lian Leon Luo, John Kramer
  • Publication number: 20090269390
    Abstract: Polymers, compositions, and medical devices useful for delivering (e.g., by local and/or sustained delivery) a haloacetate (e.g., dichoroacetate) to a tissue are disclosed herein. Such methods can be useful for treatment of diseases such as cancer.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 29, 2009
    Applicant: Medtronic, Inc.
    Inventors: Lian Leon Luo, Michael Eric Benz, Christopher M. Hobot, SuPing Lyu
  • Publication number: 20090061515
    Abstract: Methods of inhibiting or suppressing cellular proliferation are disclosed that include delivering at least one antiproliferative agent into or proximate a cell. In certain embodiments, the antiproliferative agent(s) are hydrolysis products of a biodegradable polymer (e.g., a polyketal polymer).
    Type: Application
    Filed: August 29, 2007
    Publication date: March 5, 2009
    Inventors: Michael Eric Benz, Timothy H. Robinson, Lian Leon Luo, Jesus Casas-Bejar, Maura Donovan, Krystal King
  • Publication number: 20080213349
    Abstract: Liposome complexes are provided for site-specific delivery of pharmaceutical agents with improved targeting efficiency. The liposome complexes include a pharmaceutical agent associated with the liposome; a sialic acid-containing molecule associated with the liposome; and optionally a targeting agent attached to the sialic acid-containing molecule. The invention also provides methods of making liposome complexes and their in vivo administration.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 4, 2008
    Inventors: Deepak Ramesh Thakker, Michael Eric Benz
  • Patent number: 7365134
    Abstract: Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: April 29, 2008
    Assignee: Medtronic, Inc
    Inventors: Michael Eric Benz, Christopher M. Hobot, David L. Miller, David A. Pearson, Mark A. Tapsak, Edward DiDomenico, Randall V. Sparer
  • Patent number: 7101956
    Abstract: Compounds that include diorgano groups having quaternary carbons and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.
    Type: Grant
    Filed: November 13, 2002
    Date of Patent: September 5, 2006
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Edward DiDomenico, Christopher M. Hobot, Randall V. Sparer, Kenneth B. Wagener, John E. Schwendeman
  • Patent number: 7064168
    Abstract: AnB block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: June 20, 2006
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Julie A Alkatout, SuPing Lyu
  • Patent number: 6984700
    Abstract: Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: January 10, 2006
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Christopher M. Hobot, David L. Miller, David A. Pearson, Mark A. Tapsak, Edward DiDomenico, Randall V. Sparer
  • Publication number: 20040214955
    Abstract: AnB block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.
    Type: Application
    Filed: May 10, 2004
    Publication date: October 28, 2004
    Applicant: Medtronic, Inc.
    Inventors: Michael Eric Benz, Julie A. Alkatout, SuPing Lyu
  • Patent number: 6756449
    Abstract: AnB block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: June 29, 2004
    Assignee: Medtronic, Inc.
    Inventors: Michael Eric Benz, Julie A. Alkatout, SuPing Lyu