Abstract: The invention features compositions and methods treating or preventing for age-related insulin resistance, type 2 diabetes and related disorders. The method involves depleting fTreg cells with an anti-ST2 antibody to decrease age-related fTreg accumulation and restore insulin sensitivity, thereby treating age-related insulin resistance, type 2 diabetes and related disorders.

Abstract: Example methods, apparatus, systems and articles of manufacture (e.g., physical storage media) to deduplicate common devices across multiple data sources are disclosed. An example apparatus includes instructions to identify a first device in a first data source and a second device in a second data source as a possible common device, calculate at least one of a station duration metric, a time match metric or a station path metric, the station duration metric, the time match metric based times of day that the first device tuned to a second set of stations and times of day that the second device tuned to the second set of stations, determine a score based on the at least one of the station duration metric, the time match metric, or the station path metric, and determine when the first device and the second device are a common device based on the score.

Abstract: Example methods disclosed herein include accessing common homes data for a group of common homes, the common homes data including return path data and panel meter data. Disclosed example methods also include accessing common homes data for a group of common homes, the common homes data including first return path data and corresponding panel meter data associated with respective ones of the common homes, grouping the common homes data into view segments, classifying the view segments based on whether the return path data in respective ones of the view segments has matching panel meter data to determine labeled view segments, generating features from the labeled view segments, training a machine learning algorithm based on the features, and applying second return path data to the trained machine learning algorithm to determine whether a media device associated with the second return path data is on or off.

Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.

Abstract: A discrimination system that forms a fluid column and interrogates objects within the fluid column with an excitation source. An optical arrangement collects output electromagnetic radiation emanating from the excited objects disposed within the fluid column and directs the output electromagnetic radiation to a detector. An analyzer reduces the positional dependency of the detected intensity by normalizing the value based on the position of each object.

Abstract: A transdermal treatment for erectile dysfunction includes an aqueous solution having a plurality of excipients and a combination of papaverine, phentolamine mesylate and prostaglandin E1.

Abstract: A LiDAR system includes an array of optical emitters, an objective lens optically coupling each optical emitter to a respective unique portion of a field of view, an optical switching network coupled between a laser and the array of optical emitters and a controller coupled to the optical switching network and configured to cause the optical switching network to route light from the laser to a sequence of the optical emitters according to a dynamically varying temporal pattern and to vary the temporal pattern in a way that reduces risk of eye injury from the laser light.

Abstract: A mouthpiece of an oropharyngeal exercise device including a positioning structure used to position a user's mouth on said mouthpiece, and methods for using such a mouthpiece for such exercises. A user's mouth can be positioned such that the apex of a user's tongue is positioned to complete an oropharyngeal exercise. The mouthpiece includes a lip guard. The mouthpiece can be used to guide a user's tongue to a position when completing an oropharyngeal exercise.

Abstract: Techniques and devices are disclosed for a fabrication layout device and assembly table. The device includes a table with a work surface. The work surface being a continuous surface and configured to support a plurality of railing pieces for fabrication of a railing assembly. The device further includes a beam located above the work surface. The beam is operatively coupled to the table, such that the beam moves relative to the work surface in a first direction. Attached to the beam is an ink dispenser. The ink dispenser is configured to move along the beam in a second direction different from the first direction. The ink dispenser is further configured to dispense ink onto the work surface of the table in the form of a pattern of the railing assembly. Railing pieces can be positioned on the pattern so that they can be assembled to one another.

Abstract: A toddler chair convertible to a standing platform including a foldable support frame with front and rear legs configured to stably support a standing platform and an elevated seat assembly for a toddler. The seat assembly includes a seating portion, a backrest portion, and a moveable elevating frame. The seating assembly is vertically moveable in relation to the support frame. The seating and backrest portions are moveable in relation to each other. A linkage interconnecting the seating portion and the support frame controls movement of the seating portion as the seat assembly is moved in relation to the support frame. In one configuration the seating assembly disposed generally above the platform and is operable as a seat for a child. In a second configuration, the seating portion is repositioned into general alignment with the backrest portion to allow a child to stand on the platform below.

Abstract: A contact assembly includes a contact holder having a central wall separating walls extending from a surface of the central wall defining contact tracks along the surface. A contact array is coupled to the surface and includes inner contacts arranged in pairs with contact dielectric bodies encapsulating portions of corresponding pairs of the contacts. Each pair of the contacts and the corresponding contact dielectric bodies form a contact set. The contact dielectric bodies of each contact set is spaced apart from each other and received in the corresponding contact track with the separating walls separating the contact sets from each other. A shield is coupled to the contact holder to cover the contact tracks and form shield pockets surrounding the corresponding contact tracks to provide circumferential shielding for the corresponding contact sets.

Abstract: Methods for processing and sorting sperm are disclosed. Portions of sperm sorting or staining processes may include standardizing sperm samples by adjusting the concentration of the sperm sample to a predetermined concentration and adjusting the pH of the sample to a predetermined value. Sperm may also be stained in a single staining buffer having a DNA selective dye and a quenching dye.

Abstract: A spinal fixation device includes an outer housing and an end plate assembly coupled with the outer housing. The outer housing defines an aperture and a longitudinal axis. At least a portion of the end plate assembly is slidably received within the outer housing. The end plate assembly includes a first end plate configured to engage a vertebral body, wherein the end plate assembly is selectively movable between a first position in which the first end plate is spaced apart from the outer housing and a second position in which the first end plate is adjacent the outer housing. Further, the first end plate is selectively adjustable to an angular orientation of a plurality of angular orientations with respect to the longitudinal axis of the outer housing.

Abstract: A portable exercise device that may be arranged in a number of different orientations and positions on the body of an individual. The portable exercise device includes a resistance assembly that enables a resistance of the portable exercise device to be adjusted.

Abstract: Aspects of the present disclosure involve implementations that may be used to protect neural network models against adversarial attacks by obfuscating neural network operations and architecture. Obfuscation techniques include obfuscating weights and biases of neural network nodes, obfuscating activation functions used by neural networks, as well as obfuscating neural network architecture by introducing dummy operations, dummy nodes, and dummy layers into the neural networks.

Abstract: Disclosed aspects and implementations are directed to systems and techniques for protecting cryptographic operations against side-channel attacks. In one example, polynomials associated with secret data and public data defined on a working domain having a first dimension are mapped to an auxiliary domain having a larger second dimension. The mapped polynomials are masked using masking polynomials associated with a kernel of a homomorphism transformation from the auxiliary domain to the working domain. One or more computations are then performed on the masked polynomials in the auxiliary domain and an output is transformed from the auxiliary domain to the working domain.

Abstract: A system can include one or more image sensors, a processor system, one or more output devices, and one or more computer-readable storage media. The output devices can include a printing device configured to apply a graphic on an article. The one or more computer-readable storage media storing computer-executable instructions that when executed by the processing system, cause the system to perform a method of processing an article. The instructions can include instructions to receive an image of the article from the one or more image sensors, instructions to determine a location of one or more fiducials in the image of the article, instructions to determine a print location on the article based on the location of the one or more fiducials in the image of the article, and instructions to send a signal to the printing device to print the graphic on the article at the print location.

Abstract: A method of detecting and responding to a visitor to a smart home environment via an electronic greeting system of the smart home environment, including determining that a visitor is approaching an entryway of the smart home environment; initiating a facial recognition operation while the visitor is approaching the entryway; initiating an observation window in response to the determination that a visitor is approaching the entryway; obtaining context information from one or more sensors of the smart home environment during the observation window; and at the end of the time window, initiating a response to the detected approach of the visitor based on the context information and/or an outcome of the facial recognition operation.

Abstract: Compositions configured for oral use, the compositions including at least one active ingredient selected from caffeine, taurine, GABA, theanine, tryptophan, vitamin B6, vitamin B12, vitamin C, lemon balm extract, ginseng, citicoline, sunflower lecithin, or combinations thereof, are provided. The compositions include one or more fillers, including a sugar alcohol, and optionally, a lipid or binder. The compositions may be in chewable, tablet, or meltable forms.

Abstract: Embodiments of the invention are directed to methods of treating, inhibiting or attenuating a microbial infection in an individual who has or is at risk for developing such an infection, comprising the step of administering an effective amount of a StIR composition to the individual.