Patents by Inventor Michael F. McGrath
Michael F. McGrath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8431349Abstract: Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions.Type: GrantFiled: December 12, 2008Date of Patent: April 30, 2013Assignees: Monsanto Technology LLC, The Curators of the University of MissouriInventors: Nagappan Mathialagan, Robert M. Roberts, Michael F. McGrath, Jonathan Green
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Publication number: 20110076705Abstract: Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions.Type: ApplicationFiled: December 12, 2008Publication date: March 31, 2011Applicants: MONSANTO TECHNOLOGY LLC, THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Nagappan Mathialagan, Roberts M. Robert, Michael F. McGrath, Jonathan Green
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Patent number: 6844322Abstract: Methods for effecting mammary secretion of milk from an animal, without the benefit of an immediately preceding pregnancy are provided. An exemplary embodiment the method comprises elevating an animal's estradiol and progesterone blood level sufficient to maintain a milk-secretion stimulating amount for approximately 5 to 12 consecutive days, wherein the day of the first elevation is defined to be day 0; and elevating an animal's somatotropin blood level sufficient to maintain a milk-secretion stimulating amount for at least 20 days from day 0. In any embodiment the method also optionally includes administering to the animal a milk-secretion stimulating amount of dexamethasone on approximately day 13 of the treatment. Furthermore, any embodiment the method may also optionally include adjusting the photo-period to which the animal is exposed in order to stimulate milk secretion. Any embodiment the method may also include physical stimulation of the animal's mammary gland.Type: GrantFiled: July 20, 2001Date of Patent: January 18, 2005Assignee: Monsanto Technology LLCInventors: Michael F. McGrath, Tim H. Klusmeyer, John L. Vicini, Robert H. Schenkel, Edward Alan Reed, Kanaiyalal R. Patel
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Publication number: 20020058621Abstract: Methods for effecting mammary secretion of milk from an animal, without the benefit of an immediately preceding pregnancy are provided. An exemplary embodiment the method comprises elevating an animal's estradiol and progesterone blood level sufficient to maintain a milk-secretion stimulating amount for approximately 5 to 12 consecutive days, wherein the day of the first elevation is defined to be day 0; and elevating an animal's somatotropin blood level sufficient to maintain a milk-secretion stimulating amount for at least 20 days from day 0. In any embodiment the method also optionally includes administering to the animal a milk-secretion stimulating amount of dexamethasone on approximately day 13 of the treatment. Furthermore, any embodiment the method may also optionally include adjusting the photo-period to which the animal is exposed in order to stimulate milk secretion. Any embodiment the method may also include physical stimulation of the animal's mammary gland.Type: ApplicationFiled: July 20, 2001Publication date: May 16, 2002Inventors: Michael F. McGrath, Tim H. Klusmeyer, John L. Vicini, Robert H. Schenkel, Edward Alan Reed, Kanaiyalal R. Patel
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Patent number: 5182302Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.Type: GrantFiled: June 28, 1991Date of Patent: January 26, 1993Assignee: Monsanto CompanyInventors: Robert J. Collier, Michael F. McGrath
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Patent number: 5130299Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.Type: GrantFiled: June 28, 1991Date of Patent: July 14, 1992Assignee: Monsanto CompanyInventors: Robert J. Collier, Michael F. McGrath
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Patent number: 5130300Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.Type: GrantFiled: March 14, 1990Date of Patent: July 14, 1992Assignee: Monsanto CompanyInventors: Robert J. Collier, Michael F. McGrath
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Patent number: 5059586Abstract: The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.Type: GrantFiled: September 2, 1987Date of Patent: October 22, 1991Assignee: Monsanto CompanyInventors: Robert J. Collier, Michael F. McGrath
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Patent number: 4981956Abstract: This invention relates to novel peptides having utility for promotion of growth and/or lactation in animals, to processes and DNA useful in production of such peptides, and to methods utilizing such peptides to promote growth or lactation in animals. In some embodiments, the invention is directed to peptides having bovine IGF-II biological activity, to production of such peptides, and to their use in effecting proliferation of certain cells (e.g. mammary epithelial or muscle) or in enhancing lactation in cattle or other animals.Type: GrantFiled: October 6, 1988Date of Patent: January 1, 1991Assignee: Monsanto CompanyInventors: Brent R. Larsen, Ned R. Siegel, Claire E. Kotts, Michael F. McGrath, Sharon D. Ogden, Gwen G. Krivi, John C. Minnerly
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Patent number: 4783524Abstract: This invention relates to novel peptides having utility for promotion of growth and/or lactation in animals, to processes and DNA useful in production of such peptides, and to methods utilizing such peptides to promote growth or lactation in animals. In some embodiments, the invention is directed to peptides having bovine IGF-II biological activity, to production of such peptides, and to their use in effecting proliferation of certain cells (e.g. mammary epithelial or muscle) or in enhancing lactation in cattle or other animals.Type: GrantFiled: July 31, 1986Date of Patent: November 8, 1988Assignee: Monsanto CompanyInventors: Brent R. Larsen, Ned R. Siegel, Claire E. Kotts, Michael F. McGrath, Sharon D. Ogden, Gwen G. Krivi, John C. Minnerly