Patents by Inventor Michael F. Ochs

Michael F. Ochs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EXPRESSION SIGNATURES ASSOCIATED WITH RESPONSE TO IMATINIB MESYLATE IN GASTROINTESTINAL STROMAL TUMORS AND USE THEREOF FOR PREDICTING PATIENT RESPONSE TO THERAPY AND IDENTIFICATION OF AGENTS WHICH HAVE EFFICACY FOR THE TREATMENT OF CANCER
    Publication number: 20150080252
    Abstract: Compositions and methods are disclosed for identifying agents useful for the treatment of malignancy, particularly GISTs which are resistant to imatinib mesylate (IM). In a preferred embodiment, agents which sensitize cancer cells to IM are provided.
    Type: Application
    Filed: August 25, 2014
    Publication date: March 19, 2015
    Inventors: Andrew K. Godwin, Burton Eisenberg, Yuliya Skorobogatko, Lori Rink, Andrew Kossenkov, Michael F. Ochs
  • GENE EXPRESSION SIGNATURES ASSOCIATED WITH RESPONSE TO IMATINIB MESYLATE IN GASTROINTESTINAL STROMAL TUMORS AND USE THEREOF FOR PREDICTING PATIENT RESPONSE TO THERAPY AND IDENTIFICATION OF AGENTS WHICH HAVE EFFICACY FOR THE TREATMENT OF CANCER
    Publication number: 20130058992
    Abstract: Compositions and methods are disclosed for identifying agents useful for the treatment of malignancy, particularly GISTs which are resistant to imatinib mesylate (IM). In a preferred embodiment, agents which sensitize cancer cells to IM are provided.
    Type: Application
    Filed: April 21, 2010
    Publication date: March 7, 2013
    Inventors: Andrew K. Godwin, Burton Eisenberg, Yuliya Skorobogatko, Lori Rink, Andrew Kossenkov, Michael F. Ochs
  • Methods of decomposing complex data
    Publication number: 20040111220
    Abstract: The invention includes a computer implemented process to identify at least one pattern and its distribution in a set of data for the purpose of interpreting the data. The process comprises (a) representing a set of data by an original data matrix D residing in a storage device, and; (b) decomposing the set of data into a set of patterns represented by a matrix F and their distribution represented by a matrix A, wherein the matrix F represents the set of patterns needed to describe the data and the matrix A represents the distribution of the set of patterns within the data matrix D, the decomposing comprising performing a Bayesian-based Monte Carlo calculation using at least the data matrix D to determine the matrices A and F, wherein the matrices A and F reconstruct the data matrix D and are more amenable to analysis than the data matrix D. Application of the process to environmental, biological and medical, econometric, and other fields is included in the invention.
    Type: Application
    Filed: December 2, 2003
    Publication date: June 10, 2004
    Applicant: Fox Chase Cancer Center
    Inventors: Michael F. Ochs, Truman R. Brown, Radka Stoyanova, Christos Patriotis