Patents by Inventor Michael F. Press

Michael F. Press has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation and characterization of , a gene overexpressed in endometrioid carcinomas of ovary and endometrium
    Patent number: 7371840
    Abstract: This invention provides an isolated polynucleotide encoding an ECA1 polypeptide. Also provided is the isolated ECA1 polypeptide Further provided is an antibody that specifically recognizes and binds the ECA1 polypeptide or an epitope thereof. The polynucleotides, antibodies and/or polypeptides of this invention may be components of compositions, host cells and/or gene delivery vehicles, where appropriate. In one aspect, the host cell will produce recombinant ECA1, which is further defined herein. In another aspect, the host cell is an antigen presenting cell such as a dendritic cell, and it will display an antigenic portion of the ECA1 polypeptide on its surface. The polypeptides, proteins and compositions of this invention are useful to aid in the diagnosis of a neoplastic condition of a cell of endometrioid origin.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: May 13, 2008
    Assignee: The University of Southern California
    Inventors: Michael F. Press, Bahman Saffari
  • Isolation and characterization of ECA1, a gene overexpressed in endometrioid carconomas of ovary and endometrium
    Publication number: 20040180339
    Abstract: This invention provides an isolated polynucleotide encoding an ECA1 polypeptide. Also provided is the isolated ECA1 polypeptide Further provided is an antibody that specifically recognizes and binds the ECA1 polypeptide or an epitope thereof. The polynucleotides, antibodies and/or polypeptides of this invention may be components of compositions, host cells and/or gene delivery vehicles, where appropriate. In one aspect, the host cell will produce recombinant ECA1, which is further defined herein. In another aspect, the host cell is an antigen presenting cell such as a dendritic cell, and it will display an antigenic portion of the ECA1 polypeptide on its surface. The polypeptides, proteins and compositions of this invention are useful to aid in the diagnosis of a neoplastic condition of a cell of endometrioid origin.
    Type: Application
    Filed: January 8, 2003
    Publication date: September 16, 2004
    Inventors: Michael F. Press, Bahman Saffari
  • Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination
    Patent number: 5846749
    Abstract: Cellular components are quantitated using stained cell samples, computerized image analysis, and cellular standards, where the computerized image analysis value can be translated into the amount of the component per cell. The methodology is demonstrated with breast cancer cells and quantitation of the HER-2/neu gene. The quantitation is shown to have prognostic capability as to the future course of the disease.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: December 8, 1998
    Assignee: The Regents of the University of California
    Inventors: Dennis J. Slamon, Michael F. Press
  • Isolation and characterization of ECA1, a gene overexpressed in endometroid carcinomas of ovary and endometrium
    Patent number: RE44024
    Abstract: This invention provides an isolated polynucleotide encoding an ECA1 polypeptide. Also provided is the isolated ECA1 polypeptide Further provided is an antibody that specifically recognizes and binds the ECA1 polypeptide or an epitope thereof. The polynucleotides, antibodies and/or polypeptides of this invention may be components of compositions, host cells and/or gene delivery vehicles, where appropriate. In one aspect, the host cell will produce recombinant ECA1, which is further defined herein. In another aspect, the host cell is an antigen presenting cell such as a dendritic cell, and it will display an antigenic portion of the ECA1 polypeptide on its surface. The polypeptides, proteins and compositions of this invention are useful to aid in the diagnosis of a neoplastic condition of a cell of endometrioid origin.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: February 19, 2013
    Assignee: The University of Southern California
    Inventors: Michael F. Press, Bahman Saffari