Patents by Inventor Michael F. Rubner
Michael F. Rubner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11400114Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).Type: GrantFiled: March 14, 2017Date of Patent: August 2, 2022Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLInventors: Roberta Polak, Robert E. Cohen, Michael F. Rubner, Elena V. Batrakova, Matthew J. Haney, Natalia L. Klyachko, Yuling Zhao
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Patent number: 11149154Abstract: A simple spray coating process can be utilized to create epoxy/HNT nanocomposites with vertically aligned nanotubes. Important mechanical properties such as modulus and hardness values can be optimized and enhanced by controlling the level of nanotube dispersion during processing and the final orientation of the nanotubes. Thus, a technologically relevant processing scheme can be used to fabricate HNT nanocomposites with a high level of control over nanotube alignment and the resulting mechanical properties.Type: GrantFiled: June 27, 2017Date of Patent: October 19, 2021Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, KHALIFA UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Robert E. Cohen, Michael F. Rubner, Dayong Chen, Roberta Polak, Kenan Song, Khalid Askar
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Patent number: 10478802Abstract: Titania-based porous nanoparticle coatings are mechanically robust, with low haze, which exhibit short time scales for decomposition of fingerprint oils under ultraviolet light. The mechanism by which a typical dactylogram is consumed combines wicking of the sebum into the nanoporous titania structure followed by photocatalytic degradation. These TiO2 nanostructured surfaces are also anti-fogging, anti-bacterial, and compatible with flexible glass substrates and remain photocatalytically active in natural sunlight.Type: GrantFiled: May 9, 2014Date of Patent: November 19, 2019Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Robert E. Cohen, Michael F. Rubner, Gareth H. McKinley, George Barbastathis, Hyungryul Johnny Choi, Kyu Chul Park, Hyo Min Lee
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Patent number: 10036833Abstract: A superhydrophilic coating on a substrate can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods. The coating can include oppositely charge inorganic nanoparticles, and can be substantially free of an organic polymer. The coating can be made mechanically robust by a hydrothermal calcination.Type: GrantFiled: November 30, 2010Date of Patent: July 31, 2018Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Zekeriyya Gemici, Michael F. Rubner, Robert E. Cohen
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Publication number: 20180002550Abstract: A simple spray coating process can be utilized to create epoxy/HNT nanocomposites with vertically aligned nanotubes. Important mechanical properties such as modulus and hardness values can be optimized and enhanced by controlling the level of nanotube dispersion during processing and the final orientation of the nanotubes. Thus, a technologically relevant processing scheme can be used to fabricate HNT nanocomposites with a high level of control over nanotube alignment and the resulting mechanical properties.Type: ApplicationFiled: June 27, 2017Publication date: January 4, 2018Applicant: Massachusetts Institute of TechnologyInventors: Robert E. Cohen, Michael F. Rubner, Dayong Chen, Roberta Polak, Kenan Song, Khalid Askar
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Publication number: 20170266317Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).Type: ApplicationFiled: March 14, 2017Publication date: September 21, 2017Applicants: Massachusetts Institute of Technology, University of North Carolina Chapel HillInventors: Roberta Polak, Robert E. Cohn, Michael F. Rubner, Elena V. Batrakova, Matthew J. Haney, Natalya L. Klyachko, Yuling Zhao
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Publication number: 20150315562Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).Type: ApplicationFiled: November 2, 2012Publication date: November 5, 2015Applicant: Massachusetts Institute of TechnologyInventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
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Patent number: 8986848Abstract: A hydrophilic coating can be applied to virtually any surface to produce a long-lasting, durable antifog effect. The coating includes a molecular-level blend of hydrophilic polymers. The coating can be assembled using a layer-by-layer assembly process.Type: GrantFiled: June 2, 2010Date of Patent: March 24, 2015Assignee: Massachusetts Institute of TechnologyInventors: Nuerxiati Nueraji, Albert J. Swiston, Michael F. Rubner, Robert E. Cohen
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Publication number: 20140336039Abstract: Titania-based porous nanoparticle coatings are mechanically robust, with low haze, which exhibit short time scales for decomposition of fingerprint oils under ultraviolet light. The mechanism by which a typical dactylogram is consumed combines wicking of the sebum into the nanoporous titania structure followed by photocatalytic degradation. These TiO2 nanostructured surfaces are also anti-fogging, anti-bacterial, and compatible with flexible glass substrates and remain photocatalytically active in natural sunlight.Type: ApplicationFiled: May 9, 2014Publication date: November 13, 2014Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Robert E. COHEN, Michael F. RUBNER, Gareth H. MCKINLEY, George BARBASTATHIS, Hyungryul Johnny CHOI, Kyoo Chul PARK, Hyomin LEE
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Publication number: 20140127774Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).Type: ApplicationFiled: November 2, 2012Publication date: May 8, 2014Applicant: Massachusetts Institute of TechnologyInventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
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Publication number: 20140112994Abstract: The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having —COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the —COO? groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.Type: ApplicationFiled: December 20, 2013Publication date: April 24, 2014Applicant: Novartis AGInventors: Michael F. Rubner, Sung Yun Yang, Yongxing Qiu Qiu, Lynn Cook Winterton, John Martin Lally
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Patent number: 8701927Abstract: A superhydrophilic thin film is formed on a metal surface of a boiler vessel to alter the wettability and roughness of the surface, which, in turn, changes the boiling behavior at the surface. The superhydrophilic film is formed by depositing a layer of a first ionic species on the surface from a solution. A second ionic species having a charge opposite to the that of the first ionic species is then deposited from solution onto the surface to produce a bilayer of the first ionic species and the oppositely charged second ionic species. The depositions are then repeated to form a plurality of bilayers, on top of the preceding bilayer. The bilayers are then heated, leaving the second ionic species on the metal surface to form a superhydrophilic film.Type: GrantFiled: February 10, 2010Date of Patent: April 22, 2014Assignee: Massachusetts Institute of TechnologyInventors: Michael F. Rubner, Jacopo Buongiorno, Lin-wen Hu, Eric Christopher Forrest, Erik Howard Williamson, Robert E. Cohen
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Patent number: 8637141Abstract: A superhydrophilic coating can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods. The coating can have a graded refractive index. The coating for wafer-level optics can be for targeted capillary condensation in nanoparticle containing reflow-compatible coatings.Type: GrantFiled: May 28, 2009Date of Patent: January 28, 2014Assignee: Massachusetts Institute of TechnologyInventors: Zekeriyya Gemici, Michael F. Rubner, Robert E. Cohen
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Patent number: 8637071Abstract: The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having —COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the —COO? groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.Type: GrantFiled: October 10, 2012Date of Patent: January 28, 2014Assignee: Novartis AGInventors: Michael F. Rubner, Sung Yun Yang, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally
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Patent number: 8323637Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).Type: GrantFiled: April 9, 2009Date of Patent: December 4, 2012Assignee: Massachusetts Institute of TechnologyInventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
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Patent number: 8313798Abstract: A process for fabricating a structural color having ultraviolet reflectance is provided. The process includes providing an atomizing nozzle, a first nanoparticle solution and a second nanoparticle solution. The atomizing nozzle is used to spray a plurality of first nanoparticle solution layers, the plurality of first nanoparticle layers forming a low index of refraction stack. In some instances, a polymer solution can be sprayed before and/or after the spraying of each first nanoparticle solution layer. The atomizing nozzle is also used to spray a plurality of second nanoparticle solution layers, the plurality of second nanoparticle layers form a high index of refraction stack. Similar to the first nanoparticle solution layers, a polymer solution can be sprayed before and/or after the spraying of each second nanoparticle solution layer.Type: GrantFiled: September 29, 2010Date of Patent: November 20, 2012Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Massachusetts Institute of TechnologyInventors: Grinia Michelle Nogueira, Debasish Banerjee, Michael F. Rubner, Robert E. Cohen
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Patent number: 8309117Abstract: The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having —COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the —COO? groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.Type: GrantFiled: December 10, 2003Date of Patent: November 13, 2012Assignee: Novartis, AGInventors: Michael F. Rubner, Sung Yun Yang, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally
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Patent number: 8153233Abstract: A surface with superhydrophobic and hydrophilic or superhydrophilic regions can be made. The hydrophilic or superhydrophilic regions can selective collect water on the surface.Type: GrantFiled: September 11, 2006Date of Patent: April 10, 2012Assignee: Massachusetts Institute of TechnologyInventors: Xiaoxia Sheng, Lei Zhai, Michael F. Rubner, Robert E. Cohen
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Publication number: 20120058355Abstract: A hydrophilic coating can be applied to virtually any surface to produce a long-lasting, durable antifog effect. The coating can be biocompatible. The coating includes a molecular-level blend of hydrophilic polymers. The coating can be assembled using a layer-by-layer assembly process.Type: ApplicationFiled: August 23, 2011Publication date: March 8, 2012Inventors: Hyomin Lee, Michael F. Rubner, Robert E. Cohen
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Publication number: 20110073003Abstract: A superhydrophilic coating on a substrate can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods. The coating can include oppositely charge inorganic nanoparticles, and can be substantially free of an organic polymer. The coating can be made mechanically robust by a hydrothermal calcination.Type: ApplicationFiled: November 30, 2010Publication date: March 31, 2011Inventors: Zekeriyya Gemici, Michael F. Rubner, Robert E. Cohen