Abstract: Fitting methods for astigmatic contact lens sets that include apodized single vision lenses for lower cylinder error correction and toric lenses for higher cylinder error correction, and related astigmatic contact lens sets. An astigmatic eye with cylinder error greater than a higher designated cylinder error label power (e.g., >1.25 diopter (D)) can be fitted with a non-apodization toric lens that has a stabilization mechanism. However, an astigmatic eye with a cylinder error up to the higher designated cylinder error label power (e.g., <=1.25 diopter (D)) can be fitted with an apodized single-vision lens. The apodized single-vision lenses have an apodization profile that reduces aberrations to provide improved vision such that a larger number of astigmatic patients up to a higher cylinder error may find vision with an apodized single-vision lens acceptable, and with enhanced comfort that comes from not having a stabilization mechanism.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: Disclosed are ophthalmic devices formed by a process comprising: (a) providing a reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the reactive composition to a first activation step such that the reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) deactivating at least a portion of the covalently bound activatable free radical initiator at one or more selective regions of the crosslinked substrate network such that the crosslinked substrate network contains retained covalently bound activatable free radical initiator outside of the one or more selective regions and optionally within the one or more selective regions; (d) contacting the crosslinked sub

Abstract: Provided are compounds that may function as functionalized polymerization initiators, for instance in the manufacture of ophthalmic lenses, and to methods of such manufacture. The compounds are of formula I: wherein R1, R2, R3, R4, R5, T, p, q, and n are as defined herein.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: A method for forming an ophthalmic lens including providing a mold assembly including base and front curve molds each having a surface profile and defining and enclosing a cavity therebetween having a reactive monomer mixture for making the lens and a first polymerization initiator that is activated at a first wavelength. A light transmissive one of the molds is exposed to a source of substantially uniform actinic radiation at the first wavelength according to a predetermined exposure pattern including at least one exposure portion and at least one non-exposure portion to initiate polymerization of the reactive monomer mixture within the mold at said at least one exposure portion.

Abstract: Provided is a method for forming an ophthalmic lens as well as a lens formed by such method. The method includes the curing of a reactive monomer mixture within a mold assembly under conditions to permit incorporation of functional features into selective portions of the ophthalmic lens.

Abstract: Provided are compounds that may function as functionalized polymerization initiators, for instance in the manufacture of ophthalmic lenses, and to methods of such manufacture. The compounds are of formula I: wherein R1, R2, R3, R4, p, q, r, s, v, w, and X1 are as defined herein.

Abstract: Provided are compounds that may function as functionalized polymerization initiators, for instance in the manufacture of ophthalmic lenses, and to methods of such manufacture. The compounds are of formula I: wherein R1, R2, R3, R4, R5, T, p, q, and n are as defined herein.

Abstract: A method of measuring the thickness of an ophthalmic lens includes forming an ophthalmic lens over a convexly curved surface of a forming optic, the ophthalmic lens including a light absorptive component, and with the ophthalmic lens remaining over the convexly curved surface of the forming optic, measuring the thickness of the ophthalmic lens using information about the light absorptive component of the ophthalmic lens and an intensity reference value associated with the forming optic. The method includes passing light having a wavelength through the ophthalmic lens and the forming optic, whereupon the light absorptive component of the ophthalmic lens absorbs some of the light passing through the ophthalmic lens. The light passing through the ophthalmic lens and the forming optic, which is not absorbed by the light absorptive component of the ophthalmic lens, is used to generate an image having pixel intensity data.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: An apparatus and method for forming a contact lens includes submerging a convex optical quality surface of a forming optic in a reservoir containing Lens Reactive Mixture, projecting a first Actinic Radiation with a first wavelength through pre-selected regions of the forming optic that correspond to increased thickness in the lens to be formed for selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis; projecting a second Actinic Radiation with a different wavelength through the entire forming optic to selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis, removing the forming optic and polymerized Lens Reactive Mixture from the reservoir and applying a Fixing Radiation to form the contact lens.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: A method of measuring the thickness of an ophthalmic lens includes forming an ophthalmic lens over a convexly curved surface of a forming optic, the ophthalmic lens including a light absorptive component, and with the ophthalmic lens remaining over the convexly curved surface of the forming optic, measuring the thickness of the ophthalmic lens using information about the light absorptive component of the ophthalmic lens and an intensity reference value associated with the forming optic. The method includes passing light having a wavelength through the ophthalmic lens and the forming optic, whereupon the light absorptive component of the ophthalmic lens absorbs some of the light passing through the ophthalmic lens. The light passing through the ophthalmic lens and the forming optic, which is not absorbed by the light absorptive component of the ophthalmic lens, is used to generate an image having pixel intensity data.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: An apparatus and method for forming a contact lens.