Patents by Inventor Michael F. Wolf
Michael F. Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220354632Abstract: The disclosure relates to systems and methods for tissue engineered grafts. The systems and methods can be used to make tissue engineered vascular grafts. The systems and methods use bioink deposited on a material having specified properties and matured under specified conditions to create the tissue engineered grafts having biomechanical properties tailored to a particular tissue.Type: ApplicationFiled: May 4, 2022Publication date: November 10, 2022Applicant: Medtronic, Inc.Inventors: Markus W Reiterer, Kimberly A. Chaffin, Michael F. Wolf
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Publication number: 20220354992Abstract: Systems and methods for tissue engineered synthetic support structures, such as grafts and patches are provided. The systems and methods can be used to make tissue engineered planar sheathes or meshes that can be fashioned into substantially planar or non-planar 3D tissue/organ structures adaptable to structure and organs within a human or mammalian body. The systems and methods can use bioink deposited on a material having specified properties and matured under specified conditions to create the tissue engineered planar sheathes or meshes having biomechanical and biological properties tailored to a particular tissue.Type: ApplicationFiled: November 18, 2021Publication date: November 10, 2022Applicants: Medtronic Inc., Sofradim ProductionInventors: Markus W. Reiterer, Kimberly A. Chaffin, Darlene P. Nebinger, Angela M. Throm Quinlan, Michael F. Wolf, Yves Bayon
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Publication number: 20220126012Abstract: A method of establishing an anastomosis utilizing a harvested blood vessel includes connecting the blood vessel to an artery, thereby forming an anastomosis therebetween. The method further includes wrapping an outer surface of the blood vessel with a tubular support. The tubular support exerts a radially-inward force on the blood vessel.Type: ApplicationFiled: October 28, 2020Publication date: April 28, 2022Inventors: Michael F. Wolf, Kenenth J. Collier, Evan D. Epstein
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Patent number: 10595868Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: July 27, 2018Date of Patent: March 24, 2020Assignee: VASCULAR GRAFT COLUTIONS LTD.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Publication number: 20190239879Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: July 27, 2018Publication date: August 8, 2019Inventors: Peter P. ZILLA, Nasser RAFIEE, Deon BEZUIDENHOUT, Thomas FRANZ, Mark YEOMAN, Hellmut C. BOWLES, Nareak DOUK, Michael F. WOLF, Paul HUMAN
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Patent number: 10092293Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: November 7, 2016Date of Patent: October 9, 2018Assignee: Neograft Technologies, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Publication number: 20170296192Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: November 7, 2016Publication date: October 19, 2017Inventors: Peter P. ZILLA, Nasser RAFIEE, Deon BEZUIDENHOUT, Thomas FRANZ, Mark YEOMAN, Hellmut C. BOWLES, Nareak DOUK, Michael F. WOLF, Paul HUMAN
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Patent number: 9517069Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: July 31, 2014Date of Patent: December 13, 2016Assignee: Neograft Technologies, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 9517121Abstract: A graft includes a flexible, resilient, generally tubular external support and a blood vessel segment, carried within and having an ablumenal surface in contact with and supported by the tubular support, the graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.Type: GrantFiled: June 11, 2009Date of Patent: December 13, 2016Assignee: Neograft Technologies, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf
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Publication number: 20140379010Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: July 31, 2014Publication date: December 25, 2014Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 8906082Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: October 8, 2013Date of Patent: December 9, 2014Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C Bowles, Nareak Douk, Michael F Wolf, Paul Human
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Publication number: 20140039352Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: October 8, 2013Publication date: February 6, 2014Applicant: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 8382814Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: August 15, 2011Date of Patent: February 26, 2013Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F Wolf, Paul Human
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Publication number: 20120116495Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.Type: ApplicationFiled: January 17, 2012Publication date: May 10, 2012Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf
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Patent number: 8172746Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.Type: GrantFiled: February 19, 2009Date of Patent: May 8, 2012Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Narenk Douk, Michael F. Wolf
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Publication number: 20110295157Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: August 15, 2011Publication date: December 1, 2011Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 8057537Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.Type: GrantFiled: April 28, 2004Date of Patent: November 15, 2011Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf
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Patent number: 7998188Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: May 4, 2007Date of Patent: August 16, 2011Assignee: Kips Bay Medical, Inc.Inventors: Peter Paul Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 7759120Abstract: Apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells, are described. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device. The introduction of the cells may occur after a blood centrifugation product, such as platelet-poor plasma, is applied to the luminal surface. After the cells are introduced, the device is then subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward and adhere to the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient. The implantable medical device may be inserted into a protective sleeve prior to seeding the device with cells, and the sleeve may or may not be removed prior to implantation.Type: GrantFiled: September 1, 2006Date of Patent: July 20, 2010Assignee: Kps Bay Medical, Inc.Inventors: Michael F. Wolf, Laurie A. Yunker, Paul V. Trescony
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Patent number: 7759099Abstract: Apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells, are described. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device. The introduction of the cells may occur after a blood centrifugation product, such as platelet-poor plasma, is applied to the luminal surface. After the cells are introduced, the device is then subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward and adhere to the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient. The implantable medical device may be inserted into a protective sleeve prior to seeding the device with cells, and the sleeve may or may not be removed prior to implantation.Type: GrantFiled: March 2, 2006Date of Patent: July 20, 2010Assignee: Kips Bay Medical, Inc.Inventors: Michael F. Wolf, Laurie A. Yunker, Paul V. Trescony