Abstract: The present invention provides certain substituted chromane, isochromane, and dihydroisobenzofuran compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein ring A is a moiety selected from: and ring B, n, R1, R2, R2A, R3, and R3A are as defined herein. The compounds of the invention are useful as mGluR2 inhibitors, or mGluR2 negative allosteric modulators (NAMs), and may be useful in methods of treating a patient for diseases or disorders in which the mGluR2-NAM receptor is involved, such as Alzheimer's disease, cognitive impairment, mild congnitive impairment, schizophrenia and other mood disorders, pain disorders and sleep disorders, by administering to the patient a therapeutically effective amount of a compound of the invention, or a pharmaceutically acceptable salt thereof.

Abstract: According to one embodiment, a user's past content (e.g., pictures, movies, audio recordings) may be retrieved and pushed to the user's mobile device in a real-time and in a contextually-relevant manner. The pushed content may also include contextually-relevant content of others with whom the user has established a relationship to share such content.

Abstract: A device may comprise a display interface and a processor coupled to the display interface. The processor may be configured to couple to a remote network-connected device over a computer network; generate a graphic representation of the network-connected device on the display and send the generated graphic representation to the display interface. A status of the network-connected device may then be received over the computer network and cause, responsive to receiving the status of the network-connected device, the graphic representation of the network-connected device to change appearance depending upon the received state the network-connected device.

Abstract: According to one embodiment, a user's past content (e.g., pictures, movies, audio recordings) may be retrieved and pushed to the user's mobile device in a real-time and in a contextually-relevant manner. The pushed content may also include contextually-relevant content of others with whom the user has established a relationship to share such content.

Abstract: The invention provides a method of detecting impaired prefrontal cognitive function in an individual by determining the individual's COMT genotype, and associating a high activity Val allele with impaired prefrontal cognitive function (and a low activity Met allele with enhanced prefrontal cognitive function).

Abstract: An air bag large enough for several children to jump on at one time is equipped with one or more bellows centrally on the top surface providing means for children safely to propel one another for great vertical distances, being assured of cushioning of the fall when they return by the perimeter of the bag. Preferably the bag is of the constant-volume or non-stretching type so that jump-on compression of any portion of the bag results not in stretching the bag but instead efficiently snaps the bellows structure out to the full extent, and upon relaxation permits the bellows structure to collapse instead of remaining distended.Similarly the bellows structure is preferably of the non-stretch material and preferably has a top reinforcement and an elastic return which may be a spring.