Patents by Inventor Michael Fehlings

Michael Fehlings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analysis of cell populations
    Patent number: 12498370
    Abstract: Methods for evaluating the expression of one or more molecules of interest by cell types of interest within a heterogeneous population of cells are provided, comprising: (i) sorting cells of the heterogeneous population of cells into two or more cell types based on expression of one or more cell type markers by the cells; (ii) labelling the cells with target-binding molecules capable of binding to one or more molecules of interest; and (iii) analysing the cells in order to determine expression of the one or more molecules of interest by the one or more cell types of interest.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: December 16, 2025
    Assignee: ImmunoSCAPE Pte. Ltd.
    Inventor: Michael Fehlings
  • HUMAN T CELL RECEPTORS SPECIFIC FOR ANTIGENIC PEPTIDES DERIVED FROM MITOGEN-ACTIVATED PROTEIN KINASE 8 INTERACTING PROTEIN 2 (MAPK8IP2), EPSTEIN-BARR VIRUS OR HUMAN ENDOGENOUS RETROVIRUS, AND USES THEREOF
    Publication number: 20250262242
    Abstract: The present application describes T cell receptors specifically binding tumor antigen derived peptides, especially derived from Mitogen-Activated Protein Kinase 8 Interacting Protein 2 (MAPK8IP2), Epstein-Barr Virus (EBV) proteins or Human Endogenous Retrovirus (HERV), as well as engineered T cells expressing these receptors, nucleic acids encoding these T cell receptors and methods of using T cells expressing these engineered T cells in adoptive cell transfer to treat diseases in a subject.
    Type: Application
    Filed: June 15, 2023
    Publication date: August 21, 2025
    Applicant: ImmunoSCAPE Pte. Ltd.
    Inventors: Daniel MacLeod, Katja Fink, Michael Fehlings, Loan Ping Eng, Kan Xing Wu, Alessandra Nardin, Xin-Zi Tang
  • ANALYSIS OF CELL POPULATIONS
    Publication number: 20220236271
    Abstract: Methods for evaluating the expression of one or more molecules of interest by cell types of interest within a heterogeneous population of cells are provided, comprising: (i) sorting cells of the heterogeneous population of cells into two or more cell types based on expression of one or more cell type markers by the cells; (ii) labelling the cells with target-binding molecules capable of binding to one or more molecules of interest; and (iii) analysing the cells in order to determine expression of the one or more molecules of interest by the one or more cell types of interest.
    Type: Application
    Filed: June 30, 2020
    Publication date: July 28, 2022
    Applicant: ImmunoSCAPE Pte.Ltd.
    Inventor: Michael Fehlings
  • Therapeutic use of IgG as a neuroprotective agent
    Patent number: 8414888
    Abstract: The present invention relates to compositions containing IgG and methods for the promotion of nerve regeneration or prevention or inhibition of neuronal degeneration by IgG to ameliorate the effects of injury, disorder or disease of the nervous system.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: April 9, 2013
    Assignee: University Health Network
    Inventors: Michael Fehlings, Sherri Robins
  • THERAPEUTIC USE OF IgG AS A NEUROPROTECTIVE AGENT
    Publication number: 20100178289
    Abstract: The present invention relates to compositions containing IgG and methods for the promotion of nerve regeneration or prevention or inhibition of neuronal degeneration by IgG to ameliorate the effects of injury, disorder or disease of the nervous system.
    Type: Application
    Filed: November 6, 2009
    Publication date: July 15, 2010
    Inventors: Michael Fehlings, Sherri Robins