Abstract: Systems and methods for detecting anomalies in aviation data communication systems (e.g., air traffic control surveillance systems), include a processor receiving device status information. A variational autoencoder receives and optimizes the device status information and determines whether it qualifies as an anomaly. Optimized device status information is compared to either non-anomalous or anomalous device status data in a latent space of the variational autoencoder. The latent space preferably includes an n-D point scatter plot and hidden vector values. The processor optimizes the device status information by generating a plurality of probabilistic models of the device status information and determining which of the plurality of models is optimal. A game theoretic optimization is applied to the plurality of models, and the best model is used to generate the n-D point scatter plot in latent space. An image gradient sobel edge detector preprocesses the device status information prior to optimization.

Abstract: In an embodiment, an apparatus where encrypted data is agnostic to encryption functionality controlled by the operating system is presented. The apparatus includes a processor and memory communicatively connected to the processor. The memory includes instructions configuring the processor to receive encrypted input data for processing by an application. The processor is configured to store the encrypted input data in a communications input buffer immediately after receipt. The OS through predetermined functionality then determines where the ultimate intended destination that data in the communications input buffer should be, moves the data to that location, referred to as the application input buffer. The processor is configured to execute the receiving application. The application is configured to run one or more programs utilizing the unencrypted input data to produce output data. The application is similarly configured to internally to optionally encrypt the output data to produce encrypted output data.

Abstract: A surgical tool includes a drive housing, a drive input rotatably mounted to a bottom of the drive housing, a capstan assembly arranged within the drive housing and operatively coupled to the drive input such that rotation of the drive input correspondingly actuates the capstan assembly, a longitudinally driven gear engageable with the drive gear, a drive rod coupled to the longitudinally driven gear and extending from the drive housing to an end effector of the surgical instrument and at least one biasing member mounted to the drive housing and operatively coupled to at least one of the capstan assembly and the longitudinally driven gear. The biasing member biases the longitudinally driven gear toward a proximal position with a constant force.

Abstract: A surgical tool includes a drive housing, a drive input rotatably mounted to a bottom of the drive housing, a capstan assembly arranged within the drive housing to rotate a drive gear about a rotational axis and within a drive plane orthogonal to the rotational axis, a longitudinally driven gear engageable with the drive gear, and a drive rod operatively coupled to the longitudinally driven gear and extending from the drive housing to a knife extendable within end effector of the surgical instrument. The drive rod is aligned within the drive plane such that translation of the longitudinally driven gear induces a corresponding longitudinal translation of the drive rod within the drive.

Abstract: Systems and methods described herein provide for pressure relief valve detection and monitoring. A valve assembly includes a valve body, having an inlet and an outlet, and a valve seat insert attached to the valve body between the inlet and the outlet. The valve body also includes an indicator assembly, a disk positioned within the valve seat insert; and a stem extending between the disk and the indicator assembly. The stem includes a magnet. A magnetic sensor is operable to identify proximity of the magnet. The valve seat insert is operable to release the disk when pressure at the inlet exceeds a threshold value. The disk, when released, moves the stem and magnet into a position that is detected by the magnetic sensor, and the indicator assembly indicates a valve opening event when the position is detected.

Abstract: Systems and methods for detecting anomalies in aviation data communication systems (e.g., air traffic control surveillance systems), include a processor receiving device status information. A variational autoencoder receives and optimizes the device status information and determines whether it qualifies as an anomaly. Optimized device status information is compared to either non-anomalous or anomalous device status data in a latent space of the variational autoencoder. The latent space preferably includes an n-D point scatter plot and hidden vector values. The processor optimizes the device status information by generating a plurality of probabilistic models of the device status information and determining which of the plurality of models is optimal. A game theoretic optimization is applied to the plurality of models, and the best model is used to generate the n-D point scatter plot in latent space. An image gradient sobel edge detector preprocesses the device status information prior to optimization.

Abstract: A device mounts a large-scale optical unit, and includes a carrier plate; a rigid support surface, which is arranged on the carrier plate and is designed for mounting a bottom surface of the large-scale optical unit in a predetermined position and a predetermined orientation; and an elastic support surface, which is arranged on the carrier plate and is designed for mounting the bottom surface of the large-scale optical unit elastically. The rigid support surface is designed for mounting the large-scale optical unit at a Bessel point of the large-scale optical unit.

Abstract: Flat RF tiles for multiple band electrical steerable antennas. To improve an antenna system for a communication between a vehicle and a satellite, a planar antenna array for multiple band satellite communication includes an array of flat RF tiles. Each RF tile includes a structure of antenna elements, wherein a first antenna element arrangement is configured to radiate in an uplink and downlink portion of a first satellite communication frequency band and a second antenna element arrangement is configured to radiate in an uplink and downlink portion of a second satellite communication frequency band.

Abstract: The disclosure relates to an exhaust gas aftertreatment system with a turbine arranged in the exhaust gas line and with a main catalytic converter arranged downstream from the turbine, wherein the exhaust gas line has a bypass line and a bypass connector, wherein the bypass line opens downstream from the turbine, wherein a main particle filter and, in the bypass line, a catalytic converter are provided, wherein the bypass valve a1) is formed as a three-way valve is and forms the bypass connector a2) the bypass valve is formed as a three-way valve and is provided at the opening b1) is positioned in the bypass line, wherein an exhaust gas flap is provided upstream from the opening in the exhaust gas line b2) the exhaust gas line is formed without exhaust gas flaps downstream from the bypass connector and upstream from the opening, and the catalytic converter has a three-way coating or the respective main catalytic converter has a DOC coating.

Abstract: A surgical tool includes a drive housing having an elongate shaft extending therefrom and an end effector arranged at a distal end of the shaft. At least one linkage is pivotally coupled to a distal end of the shaft about a pivot axis, and a camming feature is defined on the at least one linkage. The camming feature includes a rounded edge between a lateral side and a proximal face of the at least one linkage such that engagement of the camming feature with the distal end of a trocar will pivot the at least one linkage into alignment with a longitudinal axis of the shaft. The camming feature edge may be arranged to provide a large moment when the linkage is articulated to a high articulation angle and a smaller moment when the linkage is articulated to lower articulation angles.

Abstract: Provided herein is a combination product comprising a methionine adenosyltransferase II alpha (MAT2A) inhibitor and a Type II protein arginine methyltransferase (Type II PRMT) inhibitor. The combination product is useful for the treatment of a variety of cancers, including solid tumors. The combination product is useful for the treatment of any number of MAT2A-associated and/or PRMT-associated diseases.

Abstract: Flat RF tiles for multiple band electrical steerable antennas. To improve an antenna system for a communication between a vehicle and a satellite, a planar antenna array for multiple band satellite communication includes an array of flat RF tiles. Each RF tile includes a structure of antenna elements, wherein a first antenna element arrangement is configured to radiate in an uplink and downlink portion of a first satellite communication frequency band and a second antenna element arrangement is configured to radiate in an uplink and downlink portion of a second satellite communication frequency band.

Abstract: A surgical tool includes a drive housing having opposing distal and proximal ends, first and second drive cable capstans arranged within the drive housing and asymmetrically aligned between the distal and proximal ends, a first drive cable extending distally from the drive housing and actuatable by operation of the first drive cable capstan, and a second drive cable extending distally from the drive housing and actuatable by operation of the second drive cable capstan. A stiffness of the first and second drive cables is equalized by adjusting one or more characteristics of one or both of the first and second drive cables.

Abstract: Systems, methods, and devices configured to build and utilize an intelligent cipher transfer object are provided. The. intelligent cipher transfer object includes a set of participants protected by cloaking patterns. A portable dynamic rule set, which includes executable code for managing access to the protected set of participants, is included within the intelligent cipher transfer object. For a given user, the intelligent cipher transfer object may provide access to some of the participants while preventing access to other participants, based on the portable dynamic rule set therein.

Abstract: A surgical tool includes a drive housing having opposing distal and proximal ends, first and second drive cable capstans arranged within the drive housing and asymmetrically aligned between the distal and proximal ends, a first drive cable extending distally from the drive housing and actuatable by operation of the first drive cable capstan, and a second drive cable extending distally from the drive housing and actuatable by operation of the second drive cable capstan. A stiffness of the first and second drive cables is equalized by adjusting one or more characteristics of one or both of the first and second drive cables.

Abstract: A surgical tool includes a drive housing, a drive input rotatably mounted to a bottom of the drive housing, a capstan assembly arranged within the drive housing and operatively coupled to the drive input such that rotation of the drive input correspondingly actuates the capstan assembly, a static actuation limiter arranged within the drive housing, and a dynamic actuation limiter provided by the capstan assembly and engageable with the static actuation limiter as the capstan assembly is actuated. Engaging the dynamic actuation limiter against the static actuation limiter stops actuation of the capstan assembly.

Abstract: Provided are systems, methods and devices for adaptive and exception-based asset tracking by geolocation, while preserving battery life, ensuring patient privacy and maintaining interoperability by preventing interference with the operation of tracked medical devices. To prevent RF interference with medical device operation, provided are methods of detecting medical device operation through detection of magnetic fields or vibrations. For patient privacy, geolocation information received from an asset tracker device is anonymized and not stored. The asset tracker device described herein may be further configured to track elevation of an asset above the ground, movement of the asset, pressure and temperature changes to the environment and accordingly modify tracking behavior. Also provided is a pairing system for physical and electronic pairing of an asset tracker device to multiple medical devices.

Abstract: Provided herein is a combination therapy and methods of using such combination therapy to treat diseases or disorders associated with MAT2A and/or Type I PRMT.

Abstract: Systems, methods, and devices configured to build and utilize an intelligent cipher transfer object are provided. The. intelligent cipher transfer object includes a set of participants protected by cloaking patterns. A portable dynamic rule set, which includes executable code for managing access to the protected set of participants, is included within the intelligent cipher transfer object. For a given user, the intelligent cipher transfer object may provide access to some of the participants while preventing access to other participants, based on the portable dynamic rule set therein.

Abstract: A small firearm includes: a receiver; a barrel including a barrel bore axis; an action including a bolt head; and a guide surface, the receiver being configured for (i) at least indirectly receiving the barrel including a locking mechanism area, a chamber, a guide area, and a muzzle arranged successively in the longitudinal direction, and (ii) at least indirectly receiving the action movably arranged within the receiver along the longitudinal direction from an open position to a closed position, the guide surface, which is within a locking space, being configured such that at least one of (i) an entry of a cartridge case under an influence of a torque during a movement of the action from a closed position to an open position is limited due to an interaction of an ejector and an extractor and (ii) an exit of the cartridge case is favored.