Abstract: An integral modified polyolefin resin/silicone elastomer layered article is provided together with a method for its production. The integral polyolefin-based resin/silicone elastomeric material article comprises a shaped layer of a polyolefin-based copolymer or grafted polyolefin. It contains silyl trialkoxy groups, carboxylic acid groups and/or —OH groups. A silicone elastomeric material layer is subsequent to being cured from a hydrosilylation curable silicone elastomer composition comprising one or more adhesion promoters.

Abstract: Implementations described and claimed herein provide an underwater vehicle includes a vehicle body having a frame enclosed by a fairing. The vehicle body extends between a proximal end and a distal end and defining an interior. A nose is disposed at the proximal end of the vehicle body. The nose has a tow system configured to move between a tow position and a stow position. A propulsion system is disposed at the distal end of the vehicle body. The propulsion system includes a plurality of control fins and a thruster. A power distribution system is housed in the interior of the vehicle body. The power distribution system includes a first power system housed in a first pressure vessel and a second power system housed in a second pressure vessel. The first pressure vessel is isolated from the second pressure vessel.

Abstract: Techniques are disclosed for a three-dimensional (3D) graphical rendering system, comprising: obtaining a first 3D graphical object, wherein the first 3D graphical object is associated with at least a first semi-transparent material, wherein the first material is associated with an adjustable density value and comprises at least a first plane (or 3D volume) with an adjustable position within a virtual environment; determining a transparency value based, at least in part, on the adjustable density value and a distance between the first plane and the first 3D graphical object (or a density of the 3D volume); and rendering, from a first viewpoint and using a first shader, at least a portion of the first 3D graphical object by applying the determined transparency value to the first material. Rendering the first 3D graphical object may further comprise blending between the first material and a second material according to the determined transparency value.

Abstract: The present disclosure relates to a robotically controlled satellite refueling tool and associated robotically controlled support and site preparation tools which facilitates on-orbit refueling by teleoperation of fill/drain valves of various designs and dimensions on satellites not originally prepared for on-orbit servicing, through the installation of quick connect safety valves, using vision-based feedback as well as feedback from sensors embedded in the refueling tool to operate a suite of adaptable and adjustable mechanisms. The refueling tool has an open architecture to allow a refueling tool vision system to see the fill/drain valve and the section of the refueling tool that is engaged with the fill/drain valve. The support tools include a blanket cutter tool, a blanket handler tool, a wire cutter tool, a gripper tool, and the site preparation tools include a B-nut removal tool and a crush seal removal tool.

Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.

Abstract: One embodiment includes a method for predicting the progression of a current state. The method obtains input information concerning time-series forecasts of a state of an entity. The input information includes baseline information known about the state of the entity at a start time; and context information that includes a vector of time-independent background variables related to the entity. The method determines a first forecast for the entity at a first timestep that is separated from the start time by a time gap. The first forecast is determined, by a point prediction model, based on the baseline information and the context information. The method derives, from an autoregressive function, a mean parameter for a probabilistic function. The mean parameter is derived based on: the first forecast; and a learnable function trained based on the time gap and context information. The method parameterizes the probabilistic function based on the mean parameter.

Abstract: A susceptor for use in a processing chamber for supporting a wafer includes a susceptor substrate having a front side and a back side opposite the front side, and a coating layer deposited on the susceptor substrate. The front side has a pocket configured to hold a wafer to be processed in a processing chamber, the pocket being textured with a first pattern. The back side is textured with a second pattern.

Abstract: A robotic system includes a robotic arm that includes a first joint that connects a first segment to a second segment, the first segment being connected at an end of the first segment opposite the first joint to a shoulder joint of the robotic arm and the second segment being connected at an end of the second segment opposite the first joint to an elbow joint of the robotic arm; and a processor coupled to the robotic arm and configured to receive an end effector trajectory and determine a motion plan to move the end effector through the end effector trajectory, including by using the first joint to vary the distance between the shoulder joint and the elbow joint, as and if needed, to realize the end effector trajectory while using the joints and links other than the first joint in a preferred pose.

Abstract: The present disclosure relates to a robotically controlled satellite refueling tool and associated robotically controlled support and site preparation tools which facilitates on-orbit refueling by teleoperation of fill/drain valves of various designs and dimensions on satellites not originally prepared for on-orbit servicing, through the installation of quick connect safety valves, using vision-based feedback as well as feedback from sensors embedded in the refueling tool to operate a suite of adaptable and adjustable mechanisms. The refueling tool has an open architecture to allow a refueling tool vision system to see the fill/drain valve and the section of the refueling tool that is engaged with the fill/drain valve. The support tools include a blanket cutter tool, a blanket handler tool, a wire cutter tool, a gripper tool, and the site preparation tools include a B-nut removal tool and a crush seal removal tool.

Abstract: The present disclosure is directed to decoupling library capture (template seeding) from cluster generation to optimise both processes. This is achieved by introducing orthogonality between the seeding and clustering primer.

Abstract: Systems and methods for determining treatment effects of a randomized control trial (RCT) in accordance with embodiments of the invention are illustrated. One embodiment includes a method for determining treatment effects. The method includes steps for receiving data from a RCT, generating result data using a set of one or more generative models, and determining treatment effects for the RCT using the generated result data.

Abstract: Provided is a composition comprising a ceria-zirconia mixed oxide, the ceria-zirconia mixed oxide being surface-modified with a perovskite type compound of formula (I); wherein formula (I) is defined by Ax-yA?yB1-zB?zO3; where: A is an ion of a metal selected from the group consisting of Li, Na, K, Cs, Mg, Sr, Ba, Ca, Y, La, Ce, Pr, Nd, and Gd; A? is an ion of a metal selected from the group consisting of Li, Na, K, Cs, Mg, Sr, Ba, Ca, Y, La, Ce, Pr, Nd, and Gd; B is an ion of a metal selected from the group consisting of Cu, Mn, Mo, Co, Fe, Ni, Cr, Ti, Zr, Al, Ga, Sc, Nb, V, W, Bi, Zn, Sn, Pt, Rh, Pd, Ru, Au, Ag, and Ir; B? is an ion of a metal selected from the group consisting of Cu, Mn, Mo, Co, Fe, Ni, Cr, Ti, Zr, Al, Ga, Sc, Nb, V, W, Bi, Zn, Sn, Pt, Rh, Pd, Ru, Au, Ag, and Ir; x is from 0.7 to 1; y is from 0 to 0.5; and z is from 0 to 0.5.

Abstract: Disclosed herein is a single use continuous recovery, flow-through harvest vessel and corresponding method for harvesting culture medium and simultaneously either leaving the microcarrier beads behind in the vessel or flowing microcarrier beads and medium back into a bioreactor.

Abstract: A package sort cell includes a robot with an end of arm tool for transporting packages from an in-feed conveyor to a selected one of a plurality of out-feed conveyors or bins, the robot receiving instruction from the package reader as to which of the plurality of conveyors or bins to hand-off the package. An end of arm tool may be in the configuration of a conveyor which may be aligned with the out-feed conveyor on a bottom up movement. The end of arm tool may also be in the configuration of a hanging carriage frame suspending a conveyor in a top down movement. A worker platform may be provided which may be movable between in-use and out-of-use positions whereby upon robot downtime, the platform may move into the in-use position for a worker to temporarily takeover the transfer functions of the robot. A plurality of sort cells may be arranged in side by side relation adjacent a like plurality of package delivery points (e.g.

Abstract: A system, in a vehicle consist configured for dual fuel operation and comprising at least one fuel car operably connectable to at least one powered vehicle via a fuel distribution path, includes an energy management processing unit. The energy management processing unit is configured to obtain a first cost of a first fuel, obtain a second cost of a second fuel, and determine a proportional ratio of the first fuel and the second fuel for each of plural power settings available for use during performance of a mission along a route. The energy management processing unit is also configured to determine a trip plan specifying power settings for corresponding plural sections of the route to perform the mission using the first cost, the second cost, and the proportional ratio for the power settings to optimize a total combined cost of fuel used during performance of the mission.

Abstract: Mechanical modifications to a spinal rod that will enable the rod to accept various coating technologies in such a way that the spinal construct's biomechanical performance is not compromised. These modifications preserve construct biomechanics in the presence of a coating and increase the bactericidal payload of an anti-infective spinal rod coating.

Abstract: A passive sensor for detecting the operation of a light source includes a photosensor which, when illuminated by the light source, delivers a voltage to a field effect transistor (FET) which can switch a circuit to control a device at a remote location. The FET transitions rapidly between very low resistance (short circuit) and very high resistance (open circuit), allowing a binary indication to be given in the circuit. The circuit can be used to charge an electrical storage device to allow later download of recent status of the lamp by detecting the charge stored in the device.

Abstract: Methods and an apparatus are provided for associating video content to keywords present on the webpage of a user computer. Furthermore, the method includes creating a link on the webpage from the keyword which displays the video file when the link is activated. In addition, a system for video content association includes a video association controller configured to receive a request for video content association when a webpage is requested by a user computer and determine whether the webpage contains at least one keyword. Furthermore, the video association controller is configured to display a link on the webpage from at least one keyword to a video file.