Patents by Inventor Michael Fleury

Michael Fleury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200366592
    Abstract: A request from a client device is received at a first one of a plurality of compute nodes at a first one of a plurality of data centers of a distributed cloud computing network. A destination of the request is determined. An optimized route for transmitting the request toward an origin server that corresponds with the destination of the request is determined, where the optimized route is based on at least in part on probe data between data centers of the distributed cloud computing network for a plurality of transit connections, and where the optimized route has an IP address that encodes an identification of which of the plurality of transit connections is to be used to deliver the request. The request is transmitted to a next hop as defined by the optimized route over the identified one of the plurality of transit connections.
    Type: Application
    Filed: May 13, 2020
    Publication date: November 19, 2020
    Inventors: Braden Ehrat, Jay A. Kreibich, Jérôme Fleury, Michael Vanderwater, Nicholas Alexander Wondra, Richard Thompson
  • Patent number: 10752599
    Abstract: In one aspect, the invention relates to a crystalline form of the structure: or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form; methods of using this crystalline form and its soluble form (I); and processes for preparing soluble (I) and crystalline (I?) forms.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: August 25, 2020
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Adam D. Hughes, Melissa Fleury, Miroslav Rapta, Venkat R. Thalladi, Gene Timothy Fass, Michael Simeone
  • Publication number: 20200157061
    Abstract: In one aspect, the invention relates to a crystalline form of the structure: or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form; methods of using this crystalline form and its soluble form (I); and processes for preparing soluble (I) and crystalline (I?) forms.
    Type: Application
    Filed: September 25, 2019
    Publication date: May 21, 2020
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Adam D. Hughes, Melissa Fleury, Miroslav Rapta, Venkat R. Thalladi, Gene Timothy Fass, Michael Simeone
  • Patent number: 9227022
    Abstract: A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: January 5, 2016
    Assignee: Medela Holding AG
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Patent number: 8663161
    Abstract: A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: March 4, 2014
    Assignee: Acacia, Inc.
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Publication number: 20130237957
    Abstract: A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.
    Type: Application
    Filed: May 2, 2013
    Publication date: September 12, 2013
    Applicant: ACACIA, INC.
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Patent number: 8403004
    Abstract: A variable flow rate controller is provided herein. The controller may have a linearly traversable switch such that the controller is primed to flush air bubbles out of the fluid system of the controller prior to administering fluidic medication to a patient. Moreover, the controller may have a plurality of valves which may be independently opened and closed by a caming surface. To close the valve, a first seal may be disposed between offset inlet and outlet to prevent fluid from flowing from the inlet to the outlet. To open the valve, the first seal is disposed on one side of both of the inlet and outlet. Fluid if permitted to flow from the inlet to the outlet.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: March 26, 2013
    Assignee: Medical Product Specialists
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Publication number: 20120271271
    Abstract: A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.
    Type: Application
    Filed: April 22, 2011
    Publication date: October 25, 2012
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Publication number: 20120118413
    Abstract: A variable flow rate controller is provided herein. The controller may have a linearly traversable switch such that the controller is primed to flush air bubbles out of the fluid system of the controller prior to administering fluidic medication to a patient. Moreover, the controller may have a plurality of valves which may be independently opened and closed by a caming surface. To close the valve, a first seal may be disposed between offset inlet and outlet to prevent fluid from flowing from the inlet to the outlet. To open the valve, the first seal is disposed on one side of both of the inlet and outlet. Fluid if permitted to flow from the inlet to the outlet.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 17, 2012
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Patent number: 8118061
    Abstract: A variable flow rate controller is provided herein. The controller may have a linearly traversable switch such that the controller is primed to flush air bubbles out of the fluid system of the controller prior to administering fluidic medication to a patient. Moreover, the controller may have a plurality of valves which may be independently opened and closed by a caming surface. To close the valve, a first seal may be disposed between offset inlet and outlet to prevent fluid from flowing from the inlet to the outlet. To open the valve, the first seal is disposed on one side of both of the inlet and outlet. Fluid if permitted to flow from the inlet to the outlet.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: February 21, 2012
    Assignee: Acacia, Inc.
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Publication number: 20090314352
    Abstract: A variable flow rate controller is provided herein. The controller may have a linearly traversable switch such that the controller is primed to flush air bubbles out of the fluid system of the controller prior to administering fluidic medication to a patient. Moreover, the controller may have a plurality of valves which may be independently opened and closed by a caming surface. To close the valve, a first seal may be disposed between offset inlet and outlet to prevent fluid from flowing from the inlet to the outlet. To open the valve, the first seal is disposed on one side of both of the inlet and outlet. Fluid if permitted to flow from the inlet to the outlet.
    Type: Application
    Filed: June 19, 2008
    Publication date: December 24, 2009
    Inventors: Dongchul D. Hyun, Michael Fleury
  • Publication number: 20070250019
    Abstract: A safety needle device is provided for protecting a user against needle-stick injuries. This needle device includes a needle housing having a distal housing opening. A needle is disposed within the needle housing and has a distal needle portion which extends away therefrom through the distal housing opening. An elongate sheath assembly surrounds the needle within the needle housing. A biasing member is engaged to the sheath assembly and is configured to apply a force thereupon towards the distal housing opening. The biasing member defines a centerline which is parallel to the needle's distal needle portion. An indexer is engaged to the biasing member and is operative to increase or decrease a spring force of the biasing member by rotating the indexer. A trigger member is engaged to the biasing member for retaining the sheath assembly within the needle housing against the force urging the sheath assembly towards the distal housing opening.
    Type: Application
    Filed: June 21, 2007
    Publication date: October 25, 2007
    Inventors: Michael Fleury, Fergie Ferguson, Dongchul Hyun
  • Publication number: 20050027264
    Abstract: A safety needle device is provided for protecting a user against needle-stick injuries. This needle device includes a needle housing having a distal housing opening. A needle is disposed within the needle housing and has a distal needle portion which extends away therefrom through the distal housing opening. An elongate sheath assembly surrounds the needle within the needle housing. A biasing member is engaged to the sheath assembly and is configured to apply a force thereupon towards the distal housing opening. The biasing member defines a centerline which is parallel to the needle's distal needle portion. An indexer is engaged to the biasing member and is operative to increase or decrease a spring force of the biasing member by rotating the indexer. A trigger member is engaged to the biasing member for retaining the sheath assembly within the needle housing against the force urging the sheath assembly towards the distal housing opening.
    Type: Application
    Filed: September 1, 2004
    Publication date: February 3, 2005
    Inventors: Michael Fleury, Fergie Ferguson, Dongchul Hyun