Patents by Inventor Michael Floren

Michael Floren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue Extracts and Related Methods
    Publication number: 20240263141
    Abstract: Provided are enriched tissue extracts and methods of making and using such extracts. The enriched tissue extracts contain biologically active components. Some extracts produced by the methods contain extracellular vesicles. The methods can involve administering a physical stress on a biological sample comprising live cells or otherwise stimulating the live cells of the biological sample. Also contemplated are methods in which the biological sample does not contain live cells. The biological sample is incubated in an extraction solution for a period of time sufficient for extraction of biologically active components from the biological sample. Methods of using the extracts, or extracellular vesicles isolated therefrom, therapeutically and for in vitro purposes are also provided.
    Type: Application
    Filed: June 8, 2022
    Publication date: August 8, 2024
    Applicant: ALLOSOURCE
    Inventors: William Maslanik, Reginald Stilwell, Jeffrey Brown, Michael Floren
  • Pro-healing, pro-regenerative nanofibrous coating for medical implants
    Patent number: 11944725
    Abstract: The present invention relates to a medical implant, and more particularly, to a vascular implant having a dual coating structure for preventing in-stent restenosis and thrombosis. In one embodiment, the invention contemplates a vascular stent with a coating comprising a hydrophobic, degradable core with a coaxial sheath comprising at least one polyethylene-glycol derivative. In one embodiment, the at least one polyethylene-glycol derivative comprises polyethylene-glycol dimethacrylate.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: April 2, 2024
    Assignee: The Regents of the University of Colorado, A Body Corporate
    Inventors: Parnaz Boodagh, Wei Tan, Michael Floren
  • PRO-HEALING, PRO-REGENERATIVE NANOFIBROUS COATING FOR MEDICAL IMPLANTS
    Publication number: 20210260256
    Abstract: The present invention relates to a medical implant, and more particularly, to a vascular implant having a dual coating structure for preventing in-stent restenosis and thrombosis. In one embodiment, the invention contemplates a vascular stent with a coating comprising a hydrophobic, degradable core with a coaxial sheath comprising at least one polyethylene-glycol derivative. In one embodiment, said at least one polyethylene-glycol derivative comprises polyethylene-glycol dimethacrylate.
    Type: Application
    Filed: June 28, 2019
    Publication date: August 26, 2021
    Inventors: Parnaz Boodagh, Wei Tan, Michael Floren
  • Nanofibrous photoclickable hydrogel microarrays
    Patent number: 10352924
    Abstract: Nanofibrous hydrogel microarray systems that act as facile, high throughput platforms for in vitro drug discovery and investigation and screening of combinatorial effects of physical and biochemical cues on maturation and differentiation of mammalian cells.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: July 16, 2019
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Michael Floren, Wei Tan, Sadhana Sharma, Stephanie Bryant
  • NANOFIBROUS PHOTOCLICKABLE HYDROGEL MICROARRAYS
    Publication number: 20160202241
    Abstract: Nanofibrous hydrogel microarray systems that act as facile, high throughput platforms for in vitro drug discovery and investigation and screening of combinatorial effects of physical and biochemical cues on maturation and differentiation of mammalian cells.
    Type: Application
    Filed: January 8, 2016
    Publication date: July 14, 2016
    Inventors: Michael Floren, Wei Tan, Sadhana Sharma, Stephanie Bryant