Patents by Inventor Michael Fonstein

Michael Fonstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED BACTERIAL CELLS AND METHODS OF PRODUCING THE SAME
    Publication number: 20230410940
    Abstract: The present disclosure provides novel engineered target-biomolecule-producing bacterial strains and methods of producing the same. To engineer bacterial strains capable of producing substantial levels of a target biomolecule, the methods may implement the use of metabolic modeling and machine learning methods. The methods and bacterial strains produced by the methods may be implemented in further optimizing a biosynthetic pathway, e.g., to improve the production of a target biomolecule of interest, e.g., an amino acid, such as threonine.
    Type: Application
    Filed: February 28, 2023
    Publication date: December 21, 2023
    Applicant: UCHICAGO ARGONNE, LLC
    Inventors: Michael Fonstein, Paul D. Hanke, Bruce Parrello, Rick Stevens, Thomas S. Brettin, Christopher S. Henry
  • Stable biocatalysts for ester hydrolysis
    Patent number: 6218163
    Abstract: The instant invention encompasses isolated stable esterase enzymes characterized by the ability to remain stable at certain temperatures, substrate specificities, and activity profile.
    Type: Grant
    Filed: August 8, 1996
    Date of Patent: April 17, 2001
    Assignee: Thermogen, Inc.
    Inventors: Larry Allen, John Aikens, David Demirjian, Veronika Vonstein, Michael Fonstein, Malcolm Casadaban
  • Stable biocatalysts for ester hydrolysis
    Patent number: 6218167
    Abstract: The instant invention encompasses isolated stable esterase enzymes characterized by the ability to remain stable at certain temperatures, substrate specificities, and activity profile; the expression vectors which can express, nucleic acids which encode for, and corresponding protein amino acid sequence of such proteins.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: April 17, 2001
    Assignee: ThermoGen, Inc.
    Inventors: Larry Allen, John Aikens, David DeMirjian, Veronika Vonstein, Michael Fonstein, Malcolm Casadaban
  • Stable biocatalysts for ester hydrolysis
    Patent number: 5969121
    Abstract: The instant invention encompasses isolated stable esterase enzymes characterized by the ability to remain stable at certain temperatures, substrate specificities, and activity profile.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: October 19, 1999
    Assignee: Thermogen, Inc.
    Inventors: Larry Allen, John Aikens, Michael Fonstein, Veronika Vonstein, David Demirjian, Malcolm Casadaban