Patents by Inventor Michael Forbush
Michael Forbush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080103062Abstract: Acoustic waves are used to transfer small amounts of fluid in a non-contact manner. Acoustic waves are propagated through a pool of a source fluid in such a manner that causes the ejection of a single micro-droplet from the surface of the pool. The droplet is ejected towards a target with sufficient force to provide for contact of the droplet with the target. Because the fluid is not contacted by any fluid transfer device such as a pipette, the opportunities for contamination are minimized. Methods may be employed to transfer fluids from an array of source sites to an array of target sites, thereby enabling the precise automation of a wide variety of procedures including screening and synthesis procedures commonly used in biotechnology.Type: ApplicationFiled: December 21, 2007Publication date: May 1, 2008Inventors: Roger Williams, Tarlochan Singh, N. Mansour, Lawrence Lee, Michael Forbush
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Publication number: 20080103054Abstract: Invention methods employ the use of acoustic waves to transfer small amounts of fluid in a non-contact manner. In invention methods, acoustic waves are propagated through a separated pool of a source fluid in such a manner that causes the ejection of a single micro-droplet from the surface of the pool. The droplet is ejected towards a target with sufficient force to provide for contact of the droplet with the target. Because the fluid is not contacted by any fluid transfer device such as a pipette, the opportunities for contamination are minimized. Invention methods may be employed to transfer fluids from an array of source sites to an array of target sites, thereby enabling the precision automation of a wide variety of procedures including screening, and synthesis procedures commonly used in biotechnology.Type: ApplicationFiled: December 26, 2007Publication date: May 1, 2008Inventors: Roger WILLIAMS, Tarlochan Jutty, N. Mansour, Lawrence Lee, Michael Forbush
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Publication number: 20080092968Abstract: Acoustic waves are used to transfer small amounts of fluid in a non-contact manner. Acoustic waves are propagated through a pool of a source fluid in such a manner that causes the ejection of a single micro-droplet from the surface of the pool. The droplet is ejected towards a target with sufficient force to provide for contact of the droplet with the target. Because the fluid is not contacted by any fluid transfer device such as a pipette, the opportunities for contamination are minimized. Methods may be employed to transfer fluids from an array of source sites to an array of target sites, thereby enabling the precise automation of a wide variety of procedures including screening and synthesis procedures commonly used in biotechnology.Type: ApplicationFiled: December 17, 2007Publication date: April 24, 2008Inventors: Roger WILLIAMS, Tarlochan Singh, N. Mansour, Lawrence Lee, Michael Forbush
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Patent number: 7083117Abstract: An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.Type: GrantFiled: October 28, 2002Date of Patent: August 1, 2006Assignee: EDC Biosystems, Inc.Inventors: Roger O. Williams, Michael Van Tuyl, Michael Forbush
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Publication number: 20060011744Abstract: An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.Type: ApplicationFiled: September 21, 2005Publication date: January 19, 2006Applicant: EDC Biosystems, Inc.Inventors: Roger Williams, Michael Van Tuyl, Michael Forbush
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Patent number: 6976639Abstract: An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.Type: GrantFiled: December 6, 2001Date of Patent: December 20, 2005Assignee: EDC Biosystems, Inc.Inventors: Roger O. Williams, Michael Van Tuyl, Michael Forbush
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Publication number: 20050193805Abstract: The present invention comprises a noncontact method for measuring viscosity and/or surface tension information of a liquid in a liquid containment structure. The steps of the method include exciting a surface of the liquid with an excitation burst of acoustic energy that causes the surface to oscillate; generating a positional data set comprised of a plurality of positional measurements related to the detected position of the surface at a plurality of times after the surface is excited; generating a frequency domain data set from the positional data set, the amplitude spectrum of the frequency domain data set comprising information about the oscillation frequency of at least one vibrational mode of the of the surface as it oscillates; and processing the frequency domain data set and/or the positional data set to yield information about the surface tension and/or viscosity of the liquid. A Fast Fourier Transform technique may be used in generating the frequency domain data set.Type: ApplicationFiled: March 24, 2005Publication date: September 8, 2005Inventors: Roger Williams, James Chiao, Humphrey Chow, Michael Forbush, Andrew Rose
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Publication number: 20030116642Abstract: An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.Type: ApplicationFiled: October 28, 2002Publication date: June 26, 2003Inventors: Roger O. Williams, Michael Van Tuyl, Michael Forbush
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Publication number: 20030080208Abstract: An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.Type: ApplicationFiled: December 6, 2001Publication date: May 1, 2003Inventors: Roger O. Williams, Michael Van Tuyl, Michael Forbush