Abstract: A filling device for a vehicle, in particular a motor vehicle, includes a vehicle body flap which forms at least part of a skin of the vehicle and is designed to pivot between a first position and a second position that differs from the first position. The vehicle body flap has an opening. A container stores a fluid. A filler neck is provided on the vehicle body flap in such a way that the container can be filled with fluid in a direction of flow via the opening and the filler neck, the filler neck forming a channel that connects the opening in the vehicle body flap to the container. In the area of the opening, the channel has a filling portion in which a swell wall is formed that reduces the flow cross-section in relation to the opening located upstream of the swell wall and in relation to a portion of the channel located downstream of the swell wall.

Abstract: A hose arrangement for a motor vehicle may include a flexible elongated bellows including a plurality of radially orientated pleats and two axial longitudinal ends. The hose arrangement may also include at least one reinforcement rib which, on an outside, is coupled to a pleat tip of a respective pleat of the plurality of pleats in a material-bonded manner via two-component injection moulding. The at least one reinforcement rib may engage about the respective pleat in a circumferential direction. The at least one reinforcement rib may have at least two rib segments disposed following one another in the circumferential direction. Each of the at least two rib segments may radially cover the pleat tip by a segment angle of 30° to 310° in the circumferential direction.

Abstract: A hose arrangement for a motor vehicle may include a flexible elongated bellows including a plurality of radially orientated pleats and two axial longitudinal ends. The hose arrangement may also include at least one reinforcement rib which, on an outside, is coupled to a pleat tip of a respective pleat of the plurality of pleats in a material-bonded manner via two-component injection moulding. The at least one reinforcement rib may engage about the respective pleat in a circumferential direction. The at least one reinforcement rib may have at least two rib segments disposed following one another in the circumferential direction. Each of the at least two rib segments may radially cover the pleat tip by a segment angle of 30° to 310° in the circumferential direction.

Abstract: The present invention provides a method for preventing or treating acute or chronic graft rejection in a recipient of cell, tissue or organ allo- or xenotransplant, inflammatory or autoimmune diseases or malignant proliferative disease, comprising the use of an inhibitor of Vav. Further provided are Vav inhibitors, uses, pharmaceutical compositions and therapeutic combinations comprising Vav inhibitors, and screening methods therefore.