Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.

Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.

Abstract: The present invention provides compounds useful as mitochondrial permeability transition pore (mtPTP) inhibitors, the compounds being of Formula (I), or a pharmaceutically acceptable salt thereof wherein R1 is selected from the group of H, halogen, and C1-C3 alkyl; and R2 is selected from the group of H, CF3, and halogen; with the proviso that at least one of R1 and R2 is halogen or CF3.

Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.

Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.

Abstract: A stabilized ladder assembly stabilizes a ladder by providing support on both sides of the ladder. The assembly includes a ladder having a first front side rail, a second front side rail, a first support leg, a second support leg and a plurality of rungs coupled to and extending between the first and second front side rails. A pair of support bars is provided. One of the support bars is coupled to and extends between the first front side rail and the first support leg. One of the support bars is coupled to and extends between the second front side rail and the second support leg. A cross member is coupled to and extends between the support bars. A pair of base supports is provided and each is configured to contact a ground surface. Each of the base supports is coupled to and extends downwardly from the cross member.

Abstract: A tethered display frame has a planar backer sheet, a top sheet of transparent or translucent material overlaying the planar backer sheet, a border attached along a common periphery of the planar backer sheet and the top sheet, a plurality of straps fastened to the frame, and a fastener affixed to distal ends of each of the straps whereby the frame can be releasably fastened to an article. The border encloses the planar backer sheet and the top sheet on three sides with a fourth side providing means for a user to insert a display item between the top sheet and the planar backer sheet.

Abstract: A garment display frame that provides apparel with at least one display frame releasably incorporated into said apparel where the apparel has a part of a mating pair of fasteners and the display frame has the other part. The display frame has a border mounted to the edge of the display frame with a plastic transparent or translucent receptacle bound thereby having a pocket so that the user can insert a visual display of their choosing therein. Also, the apparel display frame has a receptacle that can be incorporated into any garment so that a user can selectively insert any picture, image, message, graphic or artwork as desired.

Abstract: A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of a cyclosporin compound.

Abstract: The extraction program and method of extraction of the present invention can be utilized by emergency response personnel to safely extract passengers from a vehicle and handle hazardous chemical spills. Another embodiment of the present invention provides for vehicle make and model recognition technology. Another embodiment provides for damage estimates to be given in a speedy manner.

Abstract: A garment display frame that provides apparel with at least one display frame releasably incorporated into said apparel where the apparel has a part of a mating pair of fasteners and the display frame has the other part. The display frame has a border mounted to the edge of the display frame with a plastic transparent or translucent receptacle bound thereby having a pocket so that the user can insert a visual display of their choosing therein. Also, the apparel display frame has a receptacle that can be incorporated into any garment so that a user can selectively insert any picture, image, message, graphic or artwork as desired.

Abstract: A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of a cyclosporin compound.

Abstract: A tethered display frame has a planar backer sheet, a top sheet of transparent or translucent material overlaying the planar backer sheet, a border attached along a common periphery of the planar backer sheet and the top sheet, a plurality of straps fastened to the frame, and a fastener affixed to distal ends of each of the straps whereby the frame can be releasably fastened to an article. The border encloses the planar backer sheet and the top sheet on three sides with a fourth side providing means for a user to insert a display item between the top sheet and the planar backer sheet.

Abstract: A garment display frame that provides apparel with at least one display frame releasably incorporated into said apparel where the apparel has a part of a mating pair of fasteners and the display frame has the other part. The display frame has a border mounted to the edge of the display frame with a plastic transparent or translucent receptacle bound thereby having a pocket so that the user can insert a visual display of their choosing therein. Also, the apparel display frame has a receptacle that can be incorporated into any garment so that a user can selectively insert any picture, image, message, graphic or artwork as desired.